RL182_ARATH
ID RL182_ARATH Reviewed; 187 AA.
AC P42791; Q9M9W4;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 06-JUN-2002, sequence version 2.
DT 25-MAY-2022, entry version 143.
DE RecName: Full=60S ribosomal protein L18-2;
GN Name=RPL18B; OrderedLocusNames=At3g05590; ORFNames=F18C1.14;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia;
RX PubMed=7875584; DOI=10.1016/0378-1119(94)00730-g;
RA Baima S., Sessa G., Ruberti I., Morelli G.;
RT "A cDNA encoding Arabidopsis thaliana cytoplasmic ribosomal protein L18.";
RL Gene 153:171-174(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=11598216; DOI=10.1104/pp.010265;
RA Barakat A., Szick-Miranda K., Chang I.-F., Guyot R., Blanc G., Cooke R.,
RA Delseny M., Bailey-Serres J.;
RT "The organization of cytoplasmic ribosomal protein genes in the Arabidopsis
RT genome.";
RL Plant Physiol. 127:398-415(2001).
RN [6]
RP INTERACTION WITH NIK1.
RX PubMed=19112492; DOI=10.1371/journal.ppat.1000247;
RA Carvalho C.M., Santos A.A., Pires S.R., Rocha C.S., Saraiva D.I.,
RA Machado J.P., Mattos E.C., Fietto L.G., Fontes E.P.;
RT "Regulated nuclear trafficking of rpL10A mediated by NIK1 represents a
RT defense strategy of plant cells against virus.";
RL PLoS Pathog. 4:E1000247-E1000247(2008).
RN [7]
RP INTERACTION WITH EXA1.
RC STRAIN=cv. Columbia;
RX PubMed=28362261; DOI=10.7554/elife.23684;
RA Wu Z., Huang S., Zhang X., Wu D., Xia S., Li X.;
RT "Regulation of plant immune receptor accumulation through translational
RT repression by a glycine-tyrosine-phenylalanine (GYF) domain protein.";
RL Elife 6:0-0(2017).
CC -!- SUBUNIT: Interacts with NIK1 (PubMed:19112492). Interacts directly with
CC EXA1 (PubMed:28362261). {ECO:0000269|PubMed:19112492,
CC ECO:0000269|PubMed:28362261}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:7875584}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL18 family.
CC {ECO:0000305}.
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DR EMBL; U15741; AAA69928.1; -; mRNA.
DR EMBL; AC011620; AAF26138.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE74263.1; -; Genomic_DNA.
DR EMBL; AY037224; AAK59824.1; -; mRNA.
DR EMBL; AY060533; AAL31164.1; -; mRNA.
DR RefSeq; NP_187210.1; NM_111432.4.
DR AlphaFoldDB; P42791; -.
DR SMR; P42791; -.
DR BioGRID; 5060; 167.
DR IntAct; P42791; 1.
DR STRING; 3702.AT3G05590.1; -.
DR iPTMnet; P42791; -.
DR PaxDb; P42791; -.
DR PRIDE; P42791; -.
DR ProteomicsDB; 226922; -.
DR EnsemblPlants; AT3G05590.1; AT3G05590.1; AT3G05590.
DR GeneID; 819725; -.
DR Gramene; AT3G05590.1; AT3G05590.1; AT3G05590.
DR KEGG; ath:AT3G05590; -.
DR Araport; AT3G05590; -.
DR TAIR; locus:2078077; AT3G05590.
DR eggNOG; KOG1714; Eukaryota.
DR HOGENOM; CLU_080024_0_0_1; -.
DR InParanoid; P42791; -.
DR OMA; MSKIHRP; -.
DR OrthoDB; 1303996at2759; -.
DR PhylomeDB; P42791; -.
DR PRO; PR:P42791; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; P42791; baseline and differential.
DR Genevisible; P42791; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; HDA:TAIR.
DR GO; GO:0015934; C:large ribosomal subunit; IDA:TAIR.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0005773; C:vacuole; HDA:TAIR.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IDA:CAFA.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR InterPro; IPR036227; L18e/L15P_sf.
DR InterPro; IPR000039; Ribosomal_L18e.
DR InterPro; IPR021131; Ribosomal_L18e/L15P.
DR PANTHER; PTHR10934; PTHR10934; 1.
DR Pfam; PF17135; Ribosomal_L18; 1.
DR SUPFAM; SSF52080; SSF52080; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..187
FT /note="60S ribosomal protein L18-2"
FT /id="PRO_0000132780"
FT REGION 151..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..187
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 59
FT /note="K -> R (in Ref. 1; AAA69928)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 187 AA; 20926 MW; DDC72C02B12CBCAB CRC64;
MGIDLIAGGK SKKTKRTAPK SDDVYLKLTV KLYRFLVRRT NSKFNGVILK RLFMSKVNKA
PLSLSRLVEF MTGKEDKIAV LVGTITDDLR VHEIPAMKVT ALRFTERARA RIEKAGGECL
TFDQLALRAP LGQNTVLLRG PKNSREAVKH FGPAPGVPHS HSKPYVRAKG RKFEKARGKR
KSRGFKV
