RL18A_XENLA
ID RL18A_XENLA Reviewed; 188 AA.
AC P09897;
DT 01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=60S ribosomal protein L18-A;
DE AltName: Full=L14A;
GN Name=rpl18-a; Synonyms=rpl14a;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Oocyte;
RX PubMed=3774540; DOI=10.1093/nar/14.19.7633;
RA Beccari E., Mazzetti P., Mileo A.M., Bozzoni I., Pierandrei-Amaldi P.,
RA Amaldi F.;
RT "Sequences coding for the ribosomal protein L14 in Xenopus laevis and
RT Xenopus tropicalis; homologies in the 5' untranslated region are shared
RT with other r-protein mRNAs.";
RL Nucleic Acids Res. 14:7633-7646(1986).
CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC large ribonucleoprotein complex responsible for the synthesis of
CC proteins in the cell. {ECO:0000250|UniProtKB:Q02543}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:Q02543}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q02543}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL18 family.
CC {ECO:0000305}.
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DR EMBL; X06222; CAA29570.1; -; mRNA.
DR PIR; A25766; R5XL8A.
DR AlphaFoldDB; P09897; -.
DR SMR; P09897; -.
DR Proteomes; UP000186698; Genome assembly.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0042788; C:polysomal ribosome; ISS:UniProtKB.
DR GO; GO:0005791; C:rough endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0002181; P:cytoplasmic translation; ISS:UniProtKB.
DR InterPro; IPR036227; L18e/L15P_sf.
DR InterPro; IPR021132; Ribosomal_L18/L18-A/B/e_CS.
DR InterPro; IPR000039; Ribosomal_L18e.
DR InterPro; IPR021131; Ribosomal_L18e/L15P.
DR PANTHER; PTHR10934; PTHR10934; 1.
DR Pfam; PF17135; Ribosomal_L18; 1.
DR SUPFAM; SSF52080; SSF52080; 1.
DR PROSITE; PS01106; RIBOSOMAL_L18E; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..188
FT /note="60S ribosomal protein L18-A"
FT /id="PRO_0000132773"
FT REGION 153..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..188
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 188 AA; 21635 MW; 22E5B834DE97D614 CRC64;
MGIDIRHNKD RKVRRKEPKS QDIYLRLLVK LYRFLARRTN SSFNRVVLKR LFMSRTNRPP
LSMSRLIRKM KLPRRENKTA VVVGCITADV RIHDIPKLTV CALKLTSGAR SRILKAGGQI
MTFDQLALAA PKGQNTVLLS GPRKAREVYR HFGKAPSTPH SRTKPYVLSK GRKFERARGR
RASRGYKN