ID   RL18B_XENLA             Reviewed;         188 AA.
AC   P02412;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 4.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=60S ribosomal protein L18-B;
DE   AltName: Full=L14B;
GN   Name=rpl18-b; Synonyms=rpl14b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Oocyte;
RX   PubMed=3774540; DOI=10.1093/nar/14.19.7633;
RA   Beccari E., Mazzetti P., Mileo A.M., Bozzoni I., Pierandrei-Amaldi P.,
RA   Amaldi F.;
RT   "Sequences coding for the ribosomal protein L14 in Xenopus laevis and
RT   Xenopus tropicalis; homologies in the 5' untranslated region are shared
RT   with other r-protein mRNAs.";
RL   Nucleic Acids Res. 14:7633-7646(1986).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3822843; DOI=10.1093/nar/15.4.1870;
RA   Beccari E., Mazzetti P.;
RT   "The nucleotide sequence of the ribosomal protein L14 gene of Xenopus
RT   laevis.";
RL   Nucleic Acids Res. 15:1870-1872(1987).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 33-188.
RX   PubMed=7049839; DOI=10.1016/0378-1119(82)90147-0;
RA   Amaldi F., Beccari E., Bozzoni I., Luo Z.-X., Pierandrei-Amaldi P.;
RT   "Nucleotide sequences of cloned cDNA fragments specific for six Xenopus
RT   laevis ribosomal proteins.";
RL   Gene 17:311-316(1982).
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:Q07020}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:Q07020}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:Q07020}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q07020}. Rough endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:Q95342}. Note=Detected on cytosolic polysomes
CC       (By similarity). Detected in ribosomes that are associated with the
CC       rough endoplasmic reticulum (By similarity).
CC       {ECO:0000250|UniProtKB:Q07020, ECO:0000250|UniProtKB:Q95342}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL18 family.
CC       {ECO:0000305}.
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DR   EMBL; X06223; CAB40827.1; -; mRNA.
DR   EMBL; X05025; CAA28689.1; -; Genomic_DNA.
DR   EMBL; V01439; CAA24700.1; -; mRNA.
DR   PIR; B25766; R5XL14.
DR   AlphaFoldDB; P02412; -.
DR   SMR; P02412; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0042788; C:polysomal ribosome; ISS:UniProtKB.
DR   GO; GO:0005791; C:rough endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0002181; P:cytoplasmic translation; ISS:UniProtKB.
DR   InterPro; IPR036227; L18e/L15P_sf.
DR   InterPro; IPR021132; Ribosomal_L18/L18-A/B/e_CS.
DR   InterPro; IPR000039; Ribosomal_L18e.
DR   InterPro; IPR021131; Ribosomal_L18e/L15P.
DR   PANTHER; PTHR10934; PTHR10934; 1.
DR   Pfam; PF17135; Ribosomal_L18; 1.
DR   SUPFAM; SSF52080; SSF52080; 1.
DR   PROSITE; PS01106; RIBOSOMAL_L18E; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Endoplasmic reticulum; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein.
FT   CHAIN           1..188
FT                   /note="60S ribosomal protein L18-B"
FT                   /id="PRO_0000132774"
FT   REGION          153..188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        174..188
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        33..34
FT                   /note="RF -> DI (in Ref. 3; CAA24700)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        85
FT                   /note="Y -> C (in Ref. 2; CAA28689)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        156
FT                   /note="P -> L (in Ref. 2; CAA28689)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        157
FT                   /note="G -> S (in Ref. 1; CAB40827)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   188 AA;  21728 MW;  C92ED892EA286D92 CRC64;
     MGIDIRHNKD RKVRRKEPKS QDIYLRLLVK LYRFLARRTN SSFNRVVLKR LFMSRTNRPP
     LSMSRLIRKM KLQGRENKTA VVVGYITDDV RIHDIPKLKV CALKITSGDR SRILKSGGQI
     MTFDQLALAA PKGQNTVLLS GPRKAREVYR HFGKAPGTPH SRTKPYVLSK GRKFERARGR
     RASRGYKN