ID   RL18_BOVIN              Reviewed;         188 AA.
AC   Q5E973;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=60S ribosomal protein L18;
GN   Name=RPL18;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Ascending colon;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:Q07020}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:Q07020}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:Q07020}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q07020}. Rough endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:Q95342}. Note=Detected on cytosolic polysomes
CC       (By similarity). Detected in ribosomes that are associated with the
CC       rough endoplasmic reticulum (By similarity).
CC       {ECO:0000250|UniProtKB:Q07020, ECO:0000250|UniProtKB:Q95342}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL18 family.
CC       {ECO:0000305}.
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DR   EMBL; BT021047; AAX09064.1; -; mRNA.
DR   EMBL; BC104507; AAI04508.1; -; mRNA.
DR   RefSeq; NP_001015556.1; NM_001015556.2.
DR   AlphaFoldDB; Q5E973; -.
DR   SMR; Q5E973; -.
DR   STRING; 9913.ENSBTAP00000020452; -.
DR   PaxDb; Q5E973; -.
DR   PeptideAtlas; Q5E973; -.
DR   PRIDE; Q5E973; -.
DR   Ensembl; ENSBTAT00000070298; ENSBTAP00000071295; ENSBTAG00000015388.
DR   GeneID; 509163; -.
DR   KEGG; bta:509163; -.
DR   CTD; 6141; -.
DR   VEuPathDB; HostDB:ENSBTAG00000015388; -.
DR   VGNC; VGNC:34111; RPL18.
DR   eggNOG; KOG1714; Eukaryota.
DR   GeneTree; ENSGT00390000012976; -.
DR   HOGENOM; CLU_080024_0_0_1; -.
DR   InParanoid; Q5E973; -.
DR   OrthoDB; 1303996at2759; -.
DR   TreeFam; TF300202; -.
DR   Proteomes; UP000009136; Chromosome 18.
DR   Bgee; ENSBTAG00000015388; Expressed in isthmus of fallopian tube and 106 other tissues.
DR   ExpressionAtlas; Q5E973; baseline and differential.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0042788; C:polysomal ribosome; ISS:UniProtKB.
DR   GO; GO:0005791; C:rough endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0002181; P:cytoplasmic translation; ISS:UniProtKB.
DR   InterPro; IPR036227; L18e/L15P_sf.
DR   InterPro; IPR021132; Ribosomal_L18/L18-A/B/e_CS.
DR   InterPro; IPR000039; Ribosomal_L18e.
DR   InterPro; IPR021131; Ribosomal_L18e/L15P.
DR   PANTHER; PTHR10934; PTHR10934; 1.
DR   Pfam; PF17135; Ribosomal_L18; 1.
DR   SUPFAM; SSF52080; SSF52080; 1.
DR   PROSITE; PS01106; RIBOSOMAL_L18E; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Endoplasmic reticulum; Isopeptide bond; Phosphoprotein;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; Ubl conjugation.
FT   CHAIN           1..188
FT                   /note="60S ribosomal protein L18"
FT                   /id="PRO_0000240141"
FT   REGION          150..188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..188
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         130
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q07020"
FT   MOD_RES         158
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q07020"
FT   CROSSLNK        119
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q07020"
FT   CROSSLNK        164
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q07020"
SQ   SEQUENCE   188 AA;  21535 MW;  1C0B31DFEA4A5CD7 CRC64;
     MGVDIRHNKD RKVRRKEPKS QDIYLRLLVK LYRFLARRTN STFNQVVLKR LFMSRTNRPP
     LSLSRMIRKM KLPGREGKTA VVVGTITDDV RVQEVPKLKV CALRVSSRAR SRILKAGGKI
     LTFDQLALDS PKGCGTVLLS GPRKGREVYR HFGKAPGTPH SHTKPYVRSK GRKFERARGR
     RASRGYKN