RL18_CAEEL
ID RL18_CAEEL Reviewed; 188 AA.
AC O45946;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=60S ribosomal protein L18;
GN Name=rpl-18; ORFNames=Y45F10D.12;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL18 family.
CC {ECO:0000305}.
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DR EMBL; AL021492; CAA16387.1; -; Genomic_DNA.
DR PIR; T26939; T26939.
DR RefSeq; NP_502655.1; NM_070254.4.
DR AlphaFoldDB; O45946; -.
DR SMR; O45946; -.
DR BioGRID; 43426; 91.
DR DIP; DIP-25467N; -.
DR STRING; 6239.Y45F10D.12.3; -.
DR EPD; O45946; -.
DR PaxDb; O45946; -.
DR PeptideAtlas; O45946; -.
DR EnsemblMetazoa; Y45F10D.12.1; Y45F10D.12.1; WBGene00004430.
DR GeneID; 178342; -.
DR KEGG; cel:CELE_Y45F10D.12; -.
DR UCSC; Y45F10D.12.1; c. elegans.
DR CTD; 178342; -.
DR WormBase; Y45F10D.12; CE16650; WBGene00004430; rpl-18.
DR eggNOG; KOG1714; Eukaryota.
DR GeneTree; ENSGT00390000012976; -.
DR HOGENOM; CLU_080024_0_0_1; -.
DR InParanoid; O45946; -.
DR OMA; MSKIHRP; -.
DR OrthoDB; 1303996at2759; -.
DR PhylomeDB; O45946; -.
DR Reactome; R-CEL-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-CEL-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-CEL-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-CEL-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-CEL-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-CEL-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:O45946; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00004430; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR InterPro; IPR036227; L18e/L15P_sf.
DR InterPro; IPR000039; Ribosomal_L18e.
DR InterPro; IPR021131; Ribosomal_L18e/L15P.
DR PANTHER; PTHR10934; PTHR10934; 1.
DR Pfam; PF17135; Ribosomal_L18; 1.
DR SUPFAM; SSF52080; SSF52080; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..188
FT /note="60S ribosomal protein L18"
FT /id="PRO_0000291623"
FT REGION 147..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..188
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 188 AA; 20996 MW; 31FE0945F83B9E0A CRC64;
MGIDINHKHD RVARRTAPKS ENPYLRLLSK LYAFLARRTG EKFNAIVLKR LRMSRRNRQP
LSLAKLARAV QKAGNENKTV VTLSTVTDDA RLYTVPKISV AALHVTEGAR ARILAAGGEI
ITLDQLALKS PKGENTVFLQ GPRSAREAEK HFGPAPGVPH SHTKPYVRSK GRKFERARGR
RASRAYKN
