ID   RL18_DICDI              Reviewed;         181 AA.
AC   Q54VZ4;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=60S ribosomal protein L18;
GN   Name=rpl18; ORFNames=DDB_G0279997;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   PROTEIN SEQUENCE OF 119-139, AND IDENTIFICATION BY MASS SPECTROMETRY.
RA   Bienvenut W.V., Veltman D.M., Insall R.H.;
RL   Submitted (JAN-2010) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL18 family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000035; EAL67470.1; -; Genomic_DNA.
DR   RefSeq; XP_641456.1; XM_636364.1.
DR   AlphaFoldDB; Q54VZ4; -.
DR   SMR; Q54VZ4; -.
DR   STRING; 44689.DDB0229960; -.
DR   PaxDb; Q54VZ4; -.
DR   PRIDE; Q54VZ4; -.
DR   EnsemblProtists; EAL67470; EAL67470; DDB_G0279997.
DR   GeneID; 8622342; -.
DR   KEGG; ddi:DDB_G0279997; -.
DR   dictyBase; DDB_G0279997; rpl18.
DR   eggNOG; KOG1714; Eukaryota.
DR   HOGENOM; CLU_080024_0_0_1; -.
DR   InParanoid; Q54VZ4; -.
DR   OMA; MSKIHRP; -.
DR   PhylomeDB; Q54VZ4; -.
DR   Reactome; R-DDI-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-DDI-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-DDI-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-DDI-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-DDI-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-DDI-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q54VZ4; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   InterPro; IPR036227; L18e/L15P_sf.
DR   InterPro; IPR000039; Ribosomal_L18e.
DR   InterPro; IPR021131; Ribosomal_L18e/L15P.
DR   PANTHER; PTHR10934; PTHR10934; 1.
DR   Pfam; PF17135; Ribosomal_L18; 1.
DR   SUPFAM; SSF52080; SSF52080; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Direct protein sequencing; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..181
FT                   /note="60S ribosomal protein L18"
FT                   /id="PRO_0000291625"
SQ   SEQUENCE   181 AA;  20523 MW;  75E5B859BF6C1E9F CRC64;
     MAIDKSKRFL RKTGRKTLVS QNPYHALLVK LYRFLARRTN SKFNKVVLKR LLQTKTNRPP
     VSISRIANLM KDRKSGKIAV CVGTVVDDER LLDCPKLTVC ALRFTETARS RIVKAGGKAL
     SFDQFALVRP RGNNTFLIKG VTKAREVYKH FGRAPGLPGS HARPYVRSEG IKFQRSKTRN
     P