RL18_ICTPU
ID RL18_ICTPU Reviewed; 188 AA.
AC Q90YV0;
DT 27-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=60S ribosomal protein L18;
GN Name=rpl18;
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=12609735; DOI=10.1016/s0378-1119(02)01183-6;
RA Patterson A.P., Karsi A., Feng J., Liu Z.J.;
RT "Translational machinery of channel catfish: II. Complementary DNA and
RT expression of the complete set of 47 60S ribosomal proteins.";
RL Gene 305:151-160(2003).
CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC large ribonucleoprotein complex responsible for the synthesis of
CC proteins in the cell. {ECO:0000250|UniProtKB:Q07020}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:Q07020}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000250|UniProtKB:Q07020}. Cytoplasm
CC {ECO:0000250|UniProtKB:Q07020}. Rough endoplasmic reticulum
CC {ECO:0000250|UniProtKB:Q95342}. Note=Detected on cytosolic polysomes
CC (By similarity). Detected in ribosomes that are associated with the
CC rough endoplasmic reticulum (By similarity).
CC {ECO:0000250|UniProtKB:Q07020, ECO:0000250|UniProtKB:Q95342}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL18 family.
CC {ECO:0000305}.
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DR EMBL; AF401572; AAK95144.1; -; mRNA.
DR RefSeq; NP_001187045.1; NM_001200116.1.
DR AlphaFoldDB; Q90YV0; -.
DR SMR; Q90YV0; -.
DR STRING; 7998.ENSIPUP00000011535; -.
DR GeneID; 100304533; -.
DR KEGG; ipu:100304533; -.
DR CTD; 6141; -.
DR OrthoDB; 1303996at2759; -.
DR Proteomes; UP000221080; Chromosome 1.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0042788; C:polysomal ribosome; ISS:UniProtKB.
DR GO; GO:0005791; C:rough endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0002181; P:cytoplasmic translation; ISS:UniProtKB.
DR InterPro; IPR036227; L18e/L15P_sf.
DR InterPro; IPR021132; Ribosomal_L18/L18-A/B/e_CS.
DR InterPro; IPR000039; Ribosomal_L18e.
DR InterPro; IPR021131; Ribosomal_L18e/L15P.
DR PANTHER; PTHR10934; PTHR10934; 1.
DR Pfam; PF17135; Ribosomal_L18; 1.
DR SUPFAM; SSF52080; SSF52080; 1.
DR PROSITE; PS01106; RIBOSOMAL_L18E; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Endoplasmic reticulum; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..188
FT /note="60S ribosomal protein L18"
FT /id="PRO_0000132775"
FT REGION 153..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..188
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 188 AA; 21503 MW; 26BA7F1C373D2FC8 CRC64;
MGVDIRHNKD RKVHRTEPKS QDIYLRLLVK LYRFLARRSD APFNKVVLKR LFMSKTNRPP
LALSRLIRKM KLQGRENKIA VVVGTITDDV RILNIPKLKV CALRVTAGAR RRILKAGGQV
MTFDQLAVTT PKGQGTVLLS GPRKAREVYR HFGKAPGTPH SHTKPYIRSK GRKFERARGR
RASRGYKN