RL18_MYCTU
ID RL18_MYCTU Reviewed; 122 AA.
AC P9WHD1; L0T6A3; P66076; P95068;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 03-AUG-2022, entry version 44.
DE RecName: Full=50S ribosomal protein L18 {ECO:0000255|HAMAP-Rule:MF_01337};
GN Name=rplR {ECO:0000255|HAMAP-Rule:MF_01337}; OrderedLocusNames=Rv0720;
GN ORFNames=MTCY210.39;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- FUNCTION: This is one of the proteins that binds and probably mediates
CC the attachment of the 5S RNA into the large ribosomal subunit, where it
CC forms part of the central protuberance. {ECO:0000255|HAMAP-
CC Rule:MF_01337}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit; part of the 5S
CC rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
CC {ECO:0000255|HAMAP-Rule:MF_01337}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL18 family.
CC {ECO:0000255|HAMAP-Rule:MF_01337}.
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DR EMBL; AL123456; CCP43464.1; -; Genomic_DNA.
DR PIR; C70644; C70644.
DR RefSeq; NP_215234.1; NC_000962.3.
DR RefSeq; WP_003403677.1; NZ_NVQJ01000007.1.
DR PDB; 5V7Q; EM; 3.70 A; O=1-122.
DR PDB; 7KGB; EM; 2.70 A; O=1-122.
DR PDB; 7MSC; EM; 2.97 A; O=1-122.
DR PDB; 7MSH; EM; 3.23 A; O=1-122.
DR PDB; 7MSM; EM; 2.79 A; O=1-122.
DR PDB; 7MSZ; EM; 3.10 A; O=1-122.
DR PDB; 7MT2; EM; 2.76 A; O=1-122.
DR PDB; 7MT3; EM; 2.80 A; O=1-122.
DR PDB; 7MT7; EM; 2.71 A; O=1-122.
DR PDBsum; 5V7Q; -.
DR PDBsum; 7KGB; -.
DR PDBsum; 7MSC; -.
DR PDBsum; 7MSH; -.
DR PDBsum; 7MSM; -.
DR PDBsum; 7MSZ; -.
DR PDBsum; 7MT2; -.
DR PDBsum; 7MT3; -.
DR PDBsum; 7MT7; -.
DR AlphaFoldDB; P9WHD1; -.
DR SMR; P9WHD1; -.
DR STRING; 83332.Rv0720; -.
DR PaxDb; P9WHD1; -.
DR DNASU; 888457; -.
DR GeneID; 45424685; -.
DR GeneID; 888457; -.
DR KEGG; mtu:Rv0720; -.
DR TubercuList; Rv0720; -.
DR eggNOG; COG0256; Bacteria.
DR OMA; NKQIYAQ; -.
DR PhylomeDB; P9WHD1; -.
DR PRO; PR:P9WHD1; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0008097; F:5S rRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01337_B; Ribosomal_L18_B; 1.
DR InterPro; IPR005484; Ribosomal_L18.
DR InterPro; IPR004389; Ribosomal_L18_bac-type.
DR PANTHER; PTHR12899; PTHR12899; 1.
DR Pfam; PF00861; Ribosomal_L18p; 1.
DR TIGRFAMs; TIGR00060; L18_bact; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..122
FT /note="50S ribosomal protein L18"
FT /id="PRO_0000131305"
SQ SEQUENCE 122 AA; 13184 MW; 2BFFAF576C5ABDAE CRC64;
MAQSVSATRR ISRLRRHTRL RKKLSGTAER PRLVVHRSAR HIHVQLVNDL NGTTVAAASS
IEADVRGVPG DKKARSVRVG QLIAERAKAA GIDTVVFDRG GYTYGGRIAA LADAARENGL
SF