ID   RL18_OREMO              Reviewed;         188 AA.
AC   P69090; Q9I836;
DT   15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=60S ribosomal protein L18;
GN   Name=rpl18;
OS   Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8127;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Liver;
RA   Molina A.I. Jr., Biemar F., Iyengar A., Maclean N., Martial J.A.,
RA   Muller M.;
RT   "Cloning and expression analysis of the tilapia (Oreochromis
RT   mossambicus)ribosomal protein L18 gene.";
RL   Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:Q07020}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:Q07020}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:Q07020}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q07020}. Rough endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:Q95342}. Note=Detected on cytosolic polysomes
CC       (By similarity). Detected in ribosomes that are associated with the
CC       rough endoplasmic reticulum (By similarity).
CC       {ECO:0000250|UniProtKB:Q07020, ECO:0000250|UniProtKB:Q95342}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL18 family.
CC       {ECO:0000305}.
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DR   EMBL; AF240376; AAF64459.1; -; Genomic_DNA.
DR   AlphaFoldDB; P69090; -.
DR   SMR; P69090; -.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0042788; C:polysomal ribosome; ISS:UniProtKB.
DR   GO; GO:0005791; C:rough endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0002181; P:cytoplasmic translation; ISS:UniProtKB.
DR   InterPro; IPR036227; L18e/L15P_sf.
DR   InterPro; IPR021132; Ribosomal_L18/L18-A/B/e_CS.
DR   InterPro; IPR000039; Ribosomal_L18e.
DR   InterPro; IPR021131; Ribosomal_L18e/L15P.
DR   PANTHER; PTHR10934; PTHR10934; 1.
DR   Pfam; PF17135; Ribosomal_L18; 1.
DR   SUPFAM; SSF52080; SSF52080; 1.
DR   PROSITE; PS01106; RIBOSOMAL_L18E; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Endoplasmic reticulum; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..188
FT                   /note="60S ribosomal protein L18"
FT                   /id="PRO_0000132776"
FT   REGION          153..188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        168..182
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   188 AA;  21531 MW;  B5ABC73FF40A31E4 CRC64;
     MGVDIRHNKD RKVHRKEPKS QDIYLRLLVK LYRFLARRSN APFNRVVLRR LFMSRTNRPP
     IAVSRLIRKM KLPGRENKIA VVVGTVTDDV RIQDIPKLKI CALRVTDGAR RRILKAGGQV
     MTFDQLALAS PKGQGTVLLS GPRKAREVYR HFGKAPGTPH SHTKPYVRSK GRKFERARGR
     RASCGYKN