RL18_STAA8
ID RL18_STAA8 Reviewed; 119 AA.
AC Q2FW22;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-MAR-2006, sequence version 1.
DT 25-MAY-2022, entry version 98.
DE RecName: Full=50S ribosomal protein L18 {ECO:0000255|HAMAP-Rule:MF_01337};
GN Name=rplR {ECO:0000255|HAMAP-Rule:MF_01337};
GN OrderedLocusNames=SAOUHSC_02495;
OS Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=93061;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 8325 / PS 47;
RA Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT "The Staphylococcus aureus NCTC 8325 genome.";
RL (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL D.C. (2006).
CC -!- FUNCTION: This is one of the proteins that binds and probably mediates
CC the attachment of the 5S RNA into the large ribosomal subunit, where it
CC forms part of the central protuberance. {ECO:0000255|HAMAP-
CC Rule:MF_01337}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit; part of the 5S
CC rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
CC {ECO:0000255|HAMAP-Rule:MF_01337}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL18 family.
CC {ECO:0000255|HAMAP-Rule:MF_01337}.
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DR EMBL; CP000253; ABD31514.1; -; Genomic_DNA.
DR RefSeq; WP_000623881.1; NZ_LS483365.1.
DR RefSeq; YP_500963.1; NC_007795.1.
DR PDB; 4WCE; X-ray; 3.53 A; L=1-119.
DR PDB; 4WF9; X-ray; 3.43 A; L=1-119.
DR PDB; 4WFA; X-ray; 3.39 A; L=1-119.
DR PDB; 4WFB; X-ray; 3.43 A; L=1-119.
DR PDB; 5HKV; X-ray; 3.66 A; L=1-119.
DR PDB; 5HL7; X-ray; 3.55 A; L=1-119.
DR PDB; 5LI0; EM; 3.80 A; R=1-119.
DR PDB; 5ND8; EM; 3.70 A; R=1-119.
DR PDB; 5ND9; EM; 3.70 A; R=1-119.
DR PDB; 5NRG; X-ray; 3.44 A; L=1-119.
DR PDB; 5TCU; EM; 3.90 A; LR=1-113.
DR PDB; 6DDD; EM; 3.10 A; a=1-119.
DR PDB; 6DDG; EM; 3.10 A; a=1-119.
DR PDB; 6HMA; EM; 2.65 A; M=1-119.
DR PDB; 6SJ6; EM; 3.23 A; R=1-119.
DR PDB; 6WQN; EM; 2.90 A; a=1-119.
DR PDB; 6WQQ; EM; 3.10 A; a=1-119.
DR PDB; 6WRS; EM; 3.20 A; a=1-119.
DR PDB; 6WRU; EM; 3.10 A; a=1-119.
DR PDB; 6YEF; EM; 3.20 A; R=1-119.
DR PDB; 7NHL; EM; 3.10 A; R=1-119.
DR PDB; 7NHM; EM; 3.10 A; R=1-119.
DR PDBsum; 4WCE; -.
DR PDBsum; 4WF9; -.
DR PDBsum; 4WFA; -.
DR PDBsum; 4WFB; -.
DR PDBsum; 5HKV; -.
DR PDBsum; 5HL7; -.
DR PDBsum; 5LI0; -.
DR PDBsum; 5ND8; -.
DR PDBsum; 5ND9; -.
DR PDBsum; 5NRG; -.
DR PDBsum; 5TCU; -.
DR PDBsum; 6DDD; -.
DR PDBsum; 6DDG; -.
DR PDBsum; 6HMA; -.
DR PDBsum; 6SJ6; -.
DR PDBsum; 6WQN; -.
DR PDBsum; 6WQQ; -.
DR PDBsum; 6WRS; -.
DR PDBsum; 6WRU; -.
DR PDBsum; 6YEF; -.
DR PDBsum; 7NHL; -.
DR PDBsum; 7NHM; -.
DR AlphaFoldDB; Q2FW22; -.
DR SMR; Q2FW22; -.
DR IntAct; Q2FW22; 2.
DR STRING; 1280.SAXN108_2484; -.
DR EnsemblBacteria; ABD31514; ABD31514; SAOUHSC_02495.
DR GeneID; 3920872; -.
DR KEGG; sao:SAOUHSC_02495; -.
DR PATRIC; fig|93061.5.peg.2251; -.
DR eggNOG; COG0256; Bacteria.
DR HOGENOM; CLU_098841_0_1_9; -.
DR OMA; NKQIYAQ; -.
DR PRO; PR:Q2FW22; -.
DR Proteomes; UP000008816; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0008097; F:5S rRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01337_B; Ribosomal_L18_B; 1.
DR InterPro; IPR005484; Ribosomal_L18.
DR InterPro; IPR004389; Ribosomal_L18_bac-type.
DR PANTHER; PTHR12899; PTHR12899; 1.
DR Pfam; PF00861; Ribosomal_L18p; 1.
DR TIGRFAMs; TIGR00060; L18_bact; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..119
FT /note="50S ribosomal protein L18"
FT /id="PRO_0000251374"
FT HELIX 7..18
FT /evidence="ECO:0007829|PDB:6HMA"
FT TURN 19..21
FT /evidence="ECO:0007829|PDB:6WQN"
FT TURN 23..25
FT /evidence="ECO:0007829|PDB:6WRS"
FT STRAND 26..28
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 30..35
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 40..46
FT /evidence="ECO:0007829|PDB:6HMA"
FT TURN 47..50
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 51..59
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 61..63
FT /evidence="ECO:0007829|PDB:6HMA"
FT TURN 67..69
FT /evidence="ECO:0007829|PDB:6WQN"
FT HELIX 71..86
FT /evidence="ECO:0007829|PDB:6HMA"
FT TURN 97..101
FT /evidence="ECO:0007829|PDB:4WFA"
FT HELIX 104..113
FT /evidence="ECO:0007829|PDB:6HMA"
FT TURN 114..116
FT /evidence="ECO:0007829|PDB:6HMA"
SQ SEQUENCE 119 AA; 13097 MW; 515ECF8471D6B6EB CRC64;
MISKIDKNKV RLKRHARVRT NLSGTAEKPR LNVYRSNKHI YAQIIDDNKG VTLAQASSKD
SDIATTATKV ELATKVGEAI AKKAADKGIK EIVFDRGGYL YHGRVKALAE AARESGLEF