ID   RL18_THETH              Reviewed;         112 AA.
AC   P80320;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 4.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=50S ribosomal protein L18;
DE   AltName: Full=TL24;
GN   Name=rplR; Synonyms=rpl18;
OS   Thermus thermophilus.
OC   Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
OX   NCBI_TaxID=274;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=VK1;
RX   PubMed=9249063; DOI=10.1016/s0378-1119(97)00072-3;
RA   Vysotskaya V.S., Shcherbakov D.V., Garber M.B.;
RT   "Sequencing and analysis of the Thermus thermophilus ribosomal protein gene
RT   cluster equivalent to the spectinomycin operon.";
RL   Gene 193:23-30(1997).
RN   [2]
RP   SEQUENCE REVISION TO 58-65.
RC   STRAIN=VK1;
RA   Shcherbakov D.V.;
RL   Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   BINDING TO 5S RRNA.
RC   STRAIN=VK1;
RX   PubMed=11524947; DOI=10.1023/A:1010562707875;
RA   Gongadze G.M., Perederina A.A., Meshcheriakov V.A., Fedorov R.V.,
RA   Moskalenko S.E., Rak A.V., Serganov A.A., Shcherbakov D.V., Nikonov S.V.,
RA   Garber M.B.;
RT   "The Thermus thermophilus 5S rRNA-protein complex: identification of
RT   specific binding sites for proteins L5 and L18 in 5S rRNA.";
RL   Mol. Biol. (Mosk.) 35:610-616(2001).
RN   [4]
RP   STRUCTURE BY NMR.
RX   PubMed=10959636; DOI=10.1023/a:1008319622724;
RA   Woestenenk E.A., Allard P., Gongadze G.M., Moskalenko S.E.,
RA   Shcherbakov D.V., Rak A.V., Garber M.B., Haerd T., Berglund H.;
RT   "Letter to the editor: assignment and secondary structure identification of
RT   the ribosomal protein L18 from Thermus thermophilus.";
RL   J. Biomol. NMR 17:273-274(2000).
RN   [5]
RP   STRUCTURE BY NMR OF 23-112.
RX   PubMed=11964156; DOI=10.1042/0264-6021:3630553;
RA   Woestenenk E.A., Gongadze G.M., Shcherbakov D.V., Rak A.V., Garber M.B.,
RA   Haerd T., Berglund H.;
RT   "The solution structure of ribosomal protein L18 from Thermus thermophilus
RT   reveals a conserved RNA-binding fold.";
RL   Biochem. J. 363:553-561(2002).
CC   -!- FUNCTION: This is one of the proteins that binds and probably mediates
CC       the attachment of the 5S RNA into the large ribosomal subunit, where it
CC       forms part of the central protuberance. {ECO:0000250}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit; part of the 5S
CC       rRNA/L5/L18/L25 subcomplex. Contacts the 5S and probably the 23S rRNA;
CC       has been isolated as a complex with the 5S rRNA and L5
CC       (PubMed:11524947). {ECO:0000269|PubMed:11524947}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL18 family.
CC       {ECO:0000305}.
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DR   EMBL; X90765; CAA62289.2; -; Genomic_DNA.
DR   RefSeq; WP_008633391.1; NZ_VHHQ01000024.1.
DR   PDB; 1ILY; NMR; -; A=23-112.
DR   PDBsum; 1ILY; -.
DR   AlphaFoldDB; P80320; -.
DR   BMRB; P80320; -.
DR   SMR; P80320; -.
DR   GeneID; 3169978; -.
DR   OMA; NKQIYAQ; -.
DR   EvolutionaryTrace; P80320; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01337_B; Ribosomal_L18_B; 1.
DR   InterPro; IPR005484; Ribosomal_L18.
DR   InterPro; IPR004389; Ribosomal_L18_bac-type.
DR   PANTHER; PTHR12899; PTHR12899; 1.
DR   Pfam; PF00861; Ribosomal_L18p; 1.
DR   TIGRFAMs; TIGR00060; L18_bact; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..112
FT                   /note="50S ribosomal protein L18"
FT                   /id="PRO_0000131373"
FT   STRAND          25..30
FT                   /evidence="ECO:0007829|PDB:1ILY"
FT   STRAND          35..41
FT                   /evidence="ECO:0007829|PDB:1ILY"
FT   TURN            42..45
FT                   /evidence="ECO:0007829|PDB:1ILY"
FT   STRAND          46..52
FT                   /evidence="ECO:0007829|PDB:1ILY"
FT   HELIX           53..56
FT                   /evidence="ECO:0007829|PDB:1ILY"
FT   HELIX           66..79
FT                   /evidence="ECO:0007829|PDB:1ILY"
FT   HELIX           96..108
FT                   /evidence="ECO:0007829|PDB:1ILY"
SQ   SEQUENCE   112 AA;  12612 MW;  EA2AB016AEDB0638 CRC64;
     MARLTAYERR KFRVRNRIKR TGRLRLSVFR SLKHIYAQII DDEKGVTLVS ASSLALKLKG
     NKTEVARQVG RALAEKALAL GIKQVAFDRG PYKYHGRVKA LAEGAREGGL EF