ID   RL18_TRYB2              Reviewed;         193 AA.
AC   P50885; Q385Y7;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=60S ribosomal protein L18;
GN   Name=RPL18-A; ORFNames=Tb10.6k15.0410;
GN   and
GN   Name=RPL18-B; ORFNames=Tb11.02.1840;
OS   Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=185431;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8950179; DOI=10.1016/s0167-4781(96)00144-3;
RA   Coulter L.J., Hide G.;
RT   "The cloning and sequencing of a ribosomal L18 protein from an evolutionary
RT   divergent eukaryote, Trypanosoma brucei.";
RL   Biochim. Biophys. Acta 1309:69-72(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=927/4 GUTat10.1 {ECO:0000312|Proteomes:UP000008524};
RX   PubMed=16020726; DOI=10.1126/science.1112642;
RA   Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA   Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA   Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA   Alsmark U.C.M., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA   Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA   Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA   Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA   Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA   Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA   Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA   Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA   Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA   Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA   Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA   Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA   Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA   Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA   Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.;
RT   "The genome of the African trypanosome Trypanosoma brucei.";
RL   Science 309:416-422(2005).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL18 family.
CC       {ECO:0000305}.
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DR   EMBL; U47286; AAC47428.1; -; mRNA.
DR   EMBL; CM000208; EAN78382.1; -; Genomic_DNA.
DR   EMBL; CH464491; EAN79394.1; -; Genomic_DNA.
DR   RefSeq; XP_823210.1; XM_818117.1.
DR   RefSeq; XP_828506.1; XM_823413.1.
DR   PDB; 4V8M; EM; 5.57 A; BI=1-193.
DR   PDBsum; 4V8M; -.
DR   AlphaFoldDB; P50885; -.
DR   SMR; P50885; -.
DR   IntAct; P50885; 1.
DR   STRING; 5691.EAN78382; -.
DR   PaxDb; P50885; -.
DR   GeneID; 3661727; -.
DR   GeneID; 3664868; -.
DR   KEGG; tbr:Tb10.6k15.0410; -.
DR   KEGG; tbr:Tb11.02.1840; -.
DR   VEuPathDB; TriTrypDB:Tb927.10.9880; -.
DR   VEuPathDB; TriTrypDB:Tb927.11.4300; -.
DR   eggNOG; KOG1714; Eukaryota.
DR   InParanoid; P50885; -.
DR   OMA; MSKIHRP; -.
DR   Proteomes; UP000008524; Chromosome 10.
DR   Proteomes; UP000008524; Chromosome 11 Scaffold 1.
DR   GO; GO:0005737; C:cytoplasm; IDA:GeneDB.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IDA:GeneDB.
DR   GO; GO:0005840; C:ribosome; ISM:GeneDB.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISM:GeneDB.
DR   GO; GO:0006412; P:translation; ISM:GeneDB.
DR   InterPro; IPR036227; L18e/L15P_sf.
DR   InterPro; IPR021132; Ribosomal_L18/L18-A/B/e_CS.
DR   InterPro; IPR000039; Ribosomal_L18e.
DR   InterPro; IPR021131; Ribosomal_L18e/L15P.
DR   PANTHER; PTHR10934; PTHR10934; 1.
DR   Pfam; PF17135; Ribosomal_L18; 1.
DR   SUPFAM; SSF52080; SSF52080; 1.
DR   PROSITE; PS01106; RIBOSOMAL_L18E; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein.
FT   CHAIN           1..193
FT                   /note="60S ribosomal protein L18"
FT                   /id="PRO_0000132779"
FT   REGION          158..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        179..193
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   193 AA;  21874 MW;  350856090EAD0388 CRC64;
     MGVDLTGVQK KKRVVRHHTY STNPYIKLLI KLYKFLGKRT NSPFNKLIHK RLLKSRNNRA
     PISLSRIAVC MRRRTVWLKK GKKSPIAVIV GDVLDDVRMT RIPALRICAL RFSKSARERI
     TGAGGECLTF DQLAMMAPTG KNTMLLRGRK SGRESVKHFG AAGVPGSHAK PHVSSRGKER
     QRSSKRRHAF RHK