RL19E_PYRFU
ID RL19E_PYRFU Reviewed; 150 AA.
AC Q8U016; Q9HH81;
DT 24-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=50S ribosomal protein L19e {ECO:0000255|HAMAP-Rule:MF_01475};
DE AltName: Full=Large ribosomal subunit protein eL19;
DE AltName: Full=PfeL19;
GN Name=rpl19e {ECO:0000255|HAMAP-Rule:MF_01475}; OrderedLocusNames=PF1806;
OS Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=186497;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX PubMed=11119702; DOI=10.1016/s0014-5793(00)02293-6;
RA Furumoto H., Taguchi A., Itoh T., Morinaga T., Itoh T.;
RT "5S rRNA binding proteins from the hyperthermophilic archaeon, Pyrococcus
RT furiosus.";
RL FEBS Lett. 486:195-199(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA DiRuggiero J., Robb F.T.;
RT "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT horikoshii inferred from complete genomic sequences.";
RL Genetics 152:1299-1305(1999).
RN [3] {ECO:0007744|PDB:4V6U}
RP STRUCTURE BY ELECTRON MICROSCOPY (6.60 ANGSTROMS) IN THE 70S RIBOSOME, AND
RP SUBUNIT.
RX PubMed=23222135; DOI=10.1093/nar/gks1259;
RA Armache J.P., Anger A.M., Marquez V., Franckenberg S., Frohlich T.,
RA Villa E., Berninghausen O., Thomm M., Arnold G.J., Beckmann R.,
RA Wilson D.N.;
RT "Promiscuous behaviour of archaeal ribosomal proteins: implications for
RT eukaryotic ribosome evolution.";
RL Nucleic Acids Res. 41:1284-1293(2013).
CC -!- FUNCTION: Binds to the 23S rRNA. {ECO:0000255|HAMAP-Rule:MF_01475}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01475, ECO:0000269|PubMed:10430560}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL19 family.
CC {ECO:0000255|HAMAP-Rule:MF_01475}.
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DR EMBL; AB040118; BAB13702.1; -; Genomic_DNA.
DR EMBL; AE009950; AAL81930.1; -; Genomic_DNA.
DR RefSeq; WP_011012947.1; NZ_CP023154.1.
DR PDB; 4V4N; EM; 9.00 A; Q=1-150.
DR PDB; 4V6U; EM; 6.60 A; BQ=1-150.
DR PDBsum; 4V4N; -.
DR PDBsum; 4V6U; -.
DR AlphaFoldDB; Q8U016; -.
DR SMR; Q8U016; -.
DR STRING; 186497.PF1806; -.
DR PRIDE; Q8U016; -.
DR EnsemblBacteria; AAL81930; AAL81930; PF1806.
DR GeneID; 41713625; -.
DR KEGG; pfu:PF1806; -.
DR PATRIC; fig|186497.12.peg.1877; -.
DR eggNOG; arCOG04089; Archaea.
DR HOGENOM; CLU_083919_1_1_2; -.
DR OMA; NRVWIDP; -.
DR OrthoDB; 109335at2157; -.
DR PhylomeDB; Q8U016; -.
DR Proteomes; UP000001013; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IEA:InterPro.
DR GO; GO:0070180; F:large ribosomal subunit rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd01418; Ribosomal_L19e_A; 1.
DR Gene3D; 1.10.1650.10; -; 1.
DR HAMAP; MF_01475; Ribosomal_L19e; 1.
DR InterPro; IPR035970; 60S_ribosomal_L19/L19e_sf.
DR InterPro; IPR000196; Ribosomal_L19/L19e.
DR InterPro; IPR023638; Ribosomal_L19/L19e_CS.
DR InterPro; IPR015972; Ribosomal_L19/L19e_dom1.
DR InterPro; IPR033936; Ribosomal_L19e_A.
DR InterPro; IPR039547; RPL19.
DR PANTHER; PTHR10722; PTHR10722; 1.
DR Pfam; PF01280; Ribosomal_L19e; 1.
DR SMART; SM01416; Ribosomal_L19e; 1.
DR SUPFAM; SSF48140; SSF48140; 1.
DR PROSITE; PS00526; RIBOSOMAL_L19E; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..150
FT /note="50S ribosomal protein L19e"
FT /id="PRO_0000131193"
FT REGION 55..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..88
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 37
FT /note="T -> P (in Ref. 1; BAB13702)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 150 AA; 17868 MW; 582F2F58D454FE9E CRC64;
MNTLKMQRRI AAEILKCGEN RIWIDPERID DVASAITRED IKRLIKEGVI KKKPIKGQSR
YRAKIRHEQK KKGRHRGPGS RKGKKTARMG KKELWIKTIR ALRKELRKLK AQKKIDRKTY
RMLYIRAKGG QFKNKHQLYL FLEEHGLLKK
