ID   RL19_DANRE              Reviewed;         196 AA.
AC   Q6P5L3; Q6DRK1;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=60S ribosomal protein L19;
GN   Name=rpl19; ORFNames=zgc:77733;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15256591; DOI=10.1073/pnas.0403929101;
RA   Amsterdam A., Nissen R.M., Sun Z., Swindell E.C., Farrington S.,
RA   Hopkins N.;
RT   "Identification of 315 genes essential for early zebrafish development.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:12792-12797(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:P84098}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P84098}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P84098}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL19 family.
CC       {ECO:0000305}.
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DR   EMBL; AY648758; AAT68076.1; -; mRNA.
DR   EMBL; BC062844; AAH62844.1; -; mRNA.
DR   RefSeq; NP_998373.1; NM_213208.1.
DR   AlphaFoldDB; Q6P5L3; -.
DR   SMR; Q6P5L3; -.
DR   STRING; 7955.ENSDARP00000105649; -.
DR   PaxDb; Q6P5L3; -.
DR   PRIDE; Q6P5L3; -.
DR   Ensembl; ENSDART00000121728; ENSDARP00000105649; ENSDARG00000013307.
DR   GeneID; 406489; -.
DR   KEGG; dre:406489; -.
DR   CTD; 6143; -.
DR   ZFIN; ZDB-GENE-040426-2290; rpl19.
DR   eggNOG; KOG1696; Eukaryota.
DR   GeneTree; ENSGT00390000012628; -.
DR   HOGENOM; CLU_083919_0_1_1; -.
DR   InParanoid; Q6P5L3; -.
DR   OMA; NRVWIDP; -.
DR   OrthoDB; 1437042at2759; -.
DR   PhylomeDB; Q6P5L3; -.
DR   TreeFam; TF313598; -.
DR   Reactome; R-DRE-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-DRE-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-DRE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-DRE-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-DRE-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-DRE-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-DRE-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q6P5L3; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 3.
DR   Bgee; ENSDARG00000013307; Expressed in tail bud paraxial mesoderm and 31 other tissues.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0030097; P:hemopoiesis; IMP:ZFIN.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd01417; Ribosomal_L19e_E; 1.
DR   Gene3D; 1.10.1650.10; -; 1.
DR   HAMAP; MF_01475; Ribosomal_L19e; 1.
DR   InterPro; IPR035970; 60S_ribosomal_L19/L19e_sf.
DR   InterPro; IPR000196; Ribosomal_L19/L19e.
DR   InterPro; IPR023638; Ribosomal_L19/L19e_CS.
DR   InterPro; IPR015972; Ribosomal_L19/L19e_dom1.
DR   InterPro; IPR033935; Ribosomal_L19_euka.
DR   InterPro; IPR039547; RPL19.
DR   PANTHER; PTHR10722; PTHR10722; 1.
DR   Pfam; PF01280; Ribosomal_L19e; 1.
DR   SMART; SM01416; Ribosomal_L19e; 1.
DR   SUPFAM; SSF48140; SSF48140; 1.
DR   PROSITE; PS00526; RIBOSOMAL_L19E; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..196
FT                   /note="60S ribosomal protein L19"
FT                   /id="PRO_0000131173"
FT   REGION          156..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   196 AA;  23453 MW;  8FB064826ACE2DF0 CRC64;
     MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLVKDGLI IKKPVTVHSR
     ARCRKNTLAR RKGRHMGVGK RKGTANARMP EKLCWMRRMR ILRRLLRRYR EAKKIDRHMY
     HSLYLRAKGN VFKNKRILME HIHKLKADKA RKKLLADQAE ARRTKTREAR KRREERQQAK
     KEEIIKTLSK EDETKK