RL1_STRSF
ID RL1_STRSF Reviewed; 242 AA.
AC Q07976;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=50S ribosomal protein L1 {ECO:0000255|HAMAP-Rule:MF_01318};
GN Name=rplA {ECO:0000255|HAMAP-Rule:MF_01318};
OS Streptomyces sp. (strain FRI-5).
OC Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC Streptomyces.
OX NCBI_TaxID=74574;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8506151; DOI=10.1093/nar/21.10.2524;
RA Ruengjitchatchawalya M., Okamoto S., Nihira T., Yamada M.;
RT "Nucleotide sequence of the genes encoding L11 and L1 equivalent ribosomal
RT protein from Streptomyces sp. FRI-5.";
RL Nucleic Acids Res. 21:2524-2524(1993).
CC -!- FUNCTION: Binds directly to 23S rRNA. The L1 stalk is quite mobile in
CC the ribosome, and is involved in E site tRNA release.
CC {ECO:0000255|HAMAP-Rule:MF_01318}.
CC -!- FUNCTION: Protein L1 is also a translational repressor protein, it
CC controls the translation of the L11 operon by binding to its mRNA.
CC {ECO:0000255|HAMAP-Rule:MF_01318}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01318}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL1 family.
CC {ECO:0000255|HAMAP-Rule:MF_01318}.
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DR EMBL; D14450; BAA03345.1; -; Genomic_DNA.
DR PIR; S40771; S40771.
DR AlphaFoldDB; Q07976; -.
DR SMR; Q07976; -.
DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd00403; Ribosomal_L1; 1.
DR Gene3D; 3.40.50.790; -; 1.
DR HAMAP; MF_01318_B; Ribosomal_L1_B; 1.
DR InterPro; IPR005878; Ribosom_L1_bac-type.
DR InterPro; IPR002143; Ribosomal_L1.
DR InterPro; IPR023674; Ribosomal_L1-like.
DR InterPro; IPR028364; Ribosomal_L1/biogenesis.
DR InterPro; IPR016095; Ribosomal_L1_3-a/b-sand.
DR InterPro; IPR023673; Ribosomal_L1_CS.
DR Pfam; PF00687; Ribosomal_L1; 1.
DR PIRSF; PIRSF002155; Ribosomal_L1; 1.
DR SUPFAM; SSF56808; SSF56808; 1.
DR TIGRFAMs; TIGR01169; rplA_bact; 1.
DR PROSITE; PS01199; RIBOSOMAL_L1; 1.
PE 3: Inferred from homology;
KW Repressor; Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding;
KW Translation regulation; tRNA-binding.
FT CHAIN 1..242
FT /note="50S ribosomal protein L1"
FT /id="PRO_0000125755"
SQ SEQUENCE 242 AA; 25992 MW; 9D09819560A6C919 CRC64;
MKRSKTLRAA DAKVDREKLY APLEAVRLAK ETSTTKFDAT VEVAFRLGVD PRKADQMVRG
TVNLPHGTGK TARVLVFATG DRAAAAEAAG ADIVGDDELI NEIAKGNRLN EFDAVVATPD
LMGKVGRLGR VLGPRGLMPN PKTGTVTMDV AKAVTDIKGG KIEFRVDKHS NLHFIIGKVS
FSDEQLVENY AAALDEIVRL KPSAAKGRYI KKAALSTTMG PGIQLDSNRT RNLLVEEDPA
AV