ID   RL1_SYNY3               Reviewed;         238 AA.
AC   P36236;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 126.
DE   RecName: Full=50S ribosomal protein L1 {ECO:0000255|HAMAP-Rule:MF_01318};
GN   Name=rplA {ECO:0000255|HAMAP-Rule:MF_01318};
GN   Synonyms=rpl1 {ECO:0000255|HAMAP-Rule:MF_01318}; OrderedLocusNames=sll1744;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7505271; DOI=10.1016/s0021-9258(19)74268-9;
RA   Schmidt J., Bubunenko M., Subramanian A.R.;
RT   "A novel operon organization involving the genes for chorismate synthase
RT   (aromatic biosynthesis pathway) and ribosomal GTPase center proteins (L11,
RT   L1, L10, L12: rplKAJL) in cyanobacterium Synechocystis PCC 6803.";
RL   J. Biol. Chem. 268:27447-27457(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- FUNCTION: Binds directly to 23S rRNA. The L1 stalk is quite mobile in
CC       the ribosome, and is involved in E site tRNA release.
CC       {ECO:0000255|HAMAP-Rule:MF_01318}.
CC   -!- FUNCTION: Protein L1 is also a translational repressor protein, it
CC       controls the translation of the L11 operon by binding to its mRNA.
CC       {ECO:0000255|HAMAP-Rule:MF_01318}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC       Rule:MF_01318}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL1 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01318}.
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DR   EMBL; X73005; CAA51492.1; -; Genomic_DNA.
DR   EMBL; BA000022; BAA17418.1; -; Genomic_DNA.
DR   PIR; D49316; D49316.
DR   AlphaFoldDB; P36236; -.
DR   SMR; P36236; -.
DR   STRING; 1148.1652497; -.
DR   PaxDb; P36236; -.
DR   PRIDE; P36236; -.
DR   EnsemblBacteria; BAA17418; BAA17418; BAA17418.
DR   KEGG; syn:sll1744; -.
DR   eggNOG; COG0081; Bacteria.
DR   InParanoid; P36236; -.
DR   OMA; GWTDVDV; -.
DR   PhylomeDB; P36236; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000470; P:maturation of LSU-rRNA; IBA:GO_Central.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd00403; Ribosomal_L1; 1.
DR   Gene3D; 3.40.50.790; -; 1.
DR   HAMAP; MF_01318_B; Ribosomal_L1_B; 1.
DR   InterPro; IPR005878; Ribosom_L1_bac-type.
DR   InterPro; IPR002143; Ribosomal_L1.
DR   InterPro; IPR023674; Ribosomal_L1-like.
DR   InterPro; IPR028364; Ribosomal_L1/biogenesis.
DR   InterPro; IPR016095; Ribosomal_L1_3-a/b-sand.
DR   InterPro; IPR023673; Ribosomal_L1_CS.
DR   Pfam; PF00687; Ribosomal_L1; 1.
DR   PIRSF; PIRSF002155; Ribosomal_L1; 1.
DR   SUPFAM; SSF56808; SSF56808; 1.
DR   TIGRFAMs; TIGR01169; rplA_bact; 1.
DR   PROSITE; PS01199; RIBOSOMAL_L1; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repressor; Ribonucleoprotein; Ribosomal protein;
KW   RNA-binding; rRNA-binding; Translation regulation; tRNA-binding.
FT   CHAIN           1..238
FT                   /note="50S ribosomal protein L1"
FT                   /id="PRO_0000125761"
SQ   SEQUENCE   238 AA;  25852 MW;  1DF314EFF387FB53 CRC64;
     MTKKLSKRMQ AAIAKVDDSK LYSPLEAMEL LKETATAKFD ETAEAHIRLG IDPKYSDQQI
     RTTVSLPKGT GQTVRVAVLA RGEKVKEATD AGADIAGSEE LIEEIQKGMM DFDVLIATPD
     MMPKIARLGK QLGPRGLMPS PKGGTVTADL AAAVNEFKAG KLEFRADRTG IVHVMFGKAS
     FSADDLLANL KALQETIDRN RPSGAKGRFW RTVFVSSSMG PSIPVDINAL RDLKFEDN