ID   RL21_CAEEL              Reviewed;         161 AA.
AC   P34334;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 144.
DE   RecName: Full=60S ribosomal protein L21;
GN   Name=rpl-21; ORFNames=C14B9.7;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL21 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FO080531; CCD64440.1; -; Genomic_DNA.
DR   PIR; S44757; S44757.
DR   RefSeq; NP_498774.1; NM_066373.5.
DR   AlphaFoldDB; P34334; -.
DR   SMR; P34334; -.
DR   BioGRID; 41352; 95.
DR   DIP; DIP-24597N; -.
DR   IntAct; P34334; 2.
DR   STRING; 6239.C14B9.7.1; -.
DR   EPD; P34334; -.
DR   PaxDb; P34334; -.
DR   PeptideAtlas; P34334; -.
DR   EnsemblMetazoa; C14B9.7.1; C14B9.7.1; WBGene00004433.
DR   GeneID; 176146; -.
DR   KEGG; cel:CELE_C14B9.7; -.
DR   UCSC; C14B9.7.2; c. elegans.
DR   CTD; 176146; -.
DR   WormBase; C14B9.7; CE00078; WBGene00004433; rpl-21.
DR   eggNOG; KOG1732; Eukaryota.
DR   GeneTree; ENSGT00950000182922; -.
DR   HOGENOM; CLU_103610_0_1_1; -.
DR   InParanoid; P34334; -.
DR   OMA; IIYNVTP; -.
DR   OrthoDB; 1455026at2759; -.
DR   PhylomeDB; P34334; -.
DR   Reactome; R-CEL-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-CEL-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-CEL-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-CEL-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-CEL-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-CEL-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:P34334; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00004433; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 2.30.30.70; -; 1.
DR   InterPro; IPR036948; Ribosomal_L21_sf.
DR   InterPro; IPR001147; Ribosomal_L21e.
DR   InterPro; IPR018259; Ribosomal_L21e_CS.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR20981; PTHR20981; 1.
DR   Pfam; PF01157; Ribosomal_L21e; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   PROSITE; PS01171; RIBOSOMAL_L21E; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..161
FT                   /note="60S ribosomal protein L21"
FT                   /id="PRO_0000149674"
SQ   SEQUENCE   161 AA;  18310 MW;  4F02C03F13F0D895 CRC64;
     MTNSKGLRRG TRYMFARDFR KHGVEHLSTY YTQYKRGDLV DIKTNGAFQK GMPFKAYHGR
     TGRIFNVTRG AVGIIVNKRV RGNILPKRIN IRIEHIKPSK CRTDFLNRVK SNDEKRKAAK
     SAGQPVPALK RLPVAPRGAH TVTTQNNEPE LLAPLRFEIV A