ID   RL21_DICDI              Reviewed;         160 AA.
AC   Q54X53;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=60S ribosomal protein L21;
GN   Name=rpl21; ORFNames=DDB_G0279387;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL21 family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000030; EAL67842.1; -; Genomic_DNA.
DR   RefSeq; XP_641724.1; XM_636632.1.
DR   AlphaFoldDB; Q54X53; -.
DR   SMR; Q54X53; -.
DR   STRING; 44689.DDB0229962; -.
DR   PaxDb; Q54X53; -.
DR   EnsemblProtists; EAL67842; EAL67842; DDB_G0279387.
DR   GeneID; 8621919; -.
DR   KEGG; ddi:DDB_G0279387; -.
DR   dictyBase; DDB_G0279387; rpl21.
DR   eggNOG; KOG1732; Eukaryota.
DR   HOGENOM; CLU_103610_0_1_1; -.
DR   InParanoid; Q54X53; -.
DR   OMA; IIYNVTP; -.
DR   PhylomeDB; Q54X53; -.
DR   Reactome; R-DDI-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-DDI-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-DDI-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-DDI-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-DDI-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-DDI-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q54X53; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0031012; C:extracellular matrix; HDA:dictyBase.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0009617; P:response to bacterium; HEP:dictyBase.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 2.30.30.70; -; 1.
DR   InterPro; IPR036948; Ribosomal_L21_sf.
DR   InterPro; IPR001147; Ribosomal_L21e.
DR   InterPro; IPR018259; Ribosomal_L21e_CS.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR20981; PTHR20981; 1.
DR   Pfam; PF01157; Ribosomal_L21e; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   PROSITE; PS01171; RIBOSOMAL_L21E; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..160
FT                   /note="60S ribosomal protein L21"
FT                   /id="PRO_0000326191"
SQ   SEQUENCE   160 AA;  18392 MW;  16F4D16CF64B6D22 CRC64;
     MPHSFGLRAR TRYLFSRGFR NHGLLQTTTF LRTFRLGDYV DIKATGNVHK GMPHKFYHGR
     TGRVWNVTPR AVGVIINKRV GPRIIAKKIH VRTEHVKPSN SMAAHLKRIQ ENKKAVVEAK
     KAGKWVDVRR NPAAPKDGFF VNPRNTEFVE VKPVKYELLL