ID   RL21_ENTHI              Reviewed;         166 AA.
AC   P38653;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 2.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=60S ribosomal protein L21;
GN   Name=RPL21;
OS   Entamoeba histolytica.
OC   Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC   Entamoeba.
OX   NCBI_TaxID=5759;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=200:NIH, and ATCC 30459 / HM-1:IMSS;
RX   PubMed=1484554; DOI=10.1016/0166-6851(92)90182-j;
RA   Petter R., Rozenblatt S., Nuchamowitz Y., Mirelman D.;
RT   "Linkage between actin and ribosomal protein L21 genes in Entamoeba
RT   histolytica.";
RL   Mol. Biochem. Parasitol. 56:329-333(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 30459 / HM-1:IMSS;
RX   PubMed=7959049; DOI=10.1016/0378-1119(94)90881-8;
RA   Petter R., Moshitch S., Rozenblatt S., Nuchamovitz Y., Mirelman D.;
RT   "Characterization of two distinct gene transcripts for ribosomal protein
RT   L21 from pathogenic and nonpathogenic strains of Entamoeba histolytica.";
RL   Gene 150:181-186(1994).
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL21 family.
CC       {ECO:0000305}.
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DR   EMBL; M92098; AAA29116.1; -; mRNA.
DR   EMBL; X73634; CAA52014.1; -; Genomic_DNA.
DR   PIR; A48465; A48465.
DR   AlphaFoldDB; P38653; -.
DR   SMR; P38653; -.
DR   STRING; 5759.rna_EHI_069110-1; -.
DR   VEuPathDB; AmoebaDB:EHI5A_114690; -.
DR   VEuPathDB; AmoebaDB:EHI_069110; -.
DR   VEuPathDB; AmoebaDB:KM1_310370; -.
DR   eggNOG; KOG1732; Eukaryota.
DR   OMA; IIYNVTP; -.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 2.30.30.70; -; 1.
DR   InterPro; IPR036948; Ribosomal_L21_sf.
DR   InterPro; IPR001147; Ribosomal_L21e.
DR   InterPro; IPR018259; Ribosomal_L21e_CS.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR20981; PTHR20981; 1.
DR   Pfam; PF01157; Ribosomal_L21e; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   PROSITE; PS01171; RIBOSOMAL_L21E; 1.
PE   2: Evidence at transcript level;
KW   Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..166
FT                   /note="60S ribosomal protein L21"
FT                   /id="PRO_0000149676"
FT   VARIANT         113
FT                   /note="A -> D (in strain: 200:NIH)"
FT   VARIANT         116
FT                   /note="R -> T (in strain: 200:NIH)"
FT   CONFLICT        97
FT                   /note="R -> K (in Ref. 1)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   166 AA;  18857 MW;  FAA46E235F9E5421 CRC64;
     MPLSNGRNRR TRKLFKRPFR GHGLSNTSTI LHTYKVGDYV TILCNSSIQH GLPYKAFHGK
     TGRVWNVNPH AIGVMVNKKV NNRIVVKRLH ISPEHIRPSG CQKDFLERKA AVAAIRKQNI
     QLKKEGKPLL PLPAKRLPKQ PRPAELIKGA DIKFTTVAPL KFEELY