ID   RL21_RAT                Reviewed;         160 AA.
AC   P20280;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=60S ribosomal protein L21;
GN   Name=Rpl21;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE.
RC   STRAIN=Sprague-Dawley; TISSUE=Liver;
RX   PubMed=2751657; DOI=10.1016/0006-291x(89)92005-6;
RA   Devi K.R.G., Chan Y.-L., Wool I.G.;
RT   "The primary structure of rat ribosomal protein L21.";
RL   Biochem. Biophys. Res. Commun. 162:364-370(1989).
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:P46778}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P46778}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:P46778}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P46778}. Endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:P49666}. Note=Detected on cytosolic polysomes
CC       (By similarity). Detected in ribosomes that are associated with the
CC       rough endoplasmic reticulum (By similarity).
CC       {ECO:0000250|UniProtKB:P46778, ECO:0000250|UniProtKB:P49666}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL21 family.
CC       {ECO:0000305}.
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DR   EMBL; M27905; AAA41504.1; -; mRNA.
DR   EMBL; X15216; CAA33286.1; -; mRNA.
DR   PIR; A33295; R5RT21.
DR   RefSeq; NP_445782.1; NM_053330.1.
DR   AlphaFoldDB; P20280; -.
DR   SMR; P20280; -.
DR   BioGRID; 249469; 1.
DR   STRING; 10116.ENSRNOP00000001265; -.
DR   iPTMnet; P20280; -.
DR   PhosphoSitePlus; P20280; -.
DR   SwissPalm; P20280; -.
DR   jPOST; P20280; -.
DR   PaxDb; P20280; -.
DR   PRIDE; P20280; -.
DR   GeneID; 79449; -.
DR   KEGG; rno:79449; -.
DR   CTD; 6144; -.
DR   RGD; 68390; Rpl21.
DR   eggNOG; KOG1732; Eukaryota.
DR   InParanoid; P20280; -.
DR   OrthoDB; 1455026at2759; -.
DR   PhylomeDB; P20280; -.
DR   PRO; PR:P20280; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IDA:RGD.
DR   GO; GO:0022626; C:cytosolic ribosome; ISO:RGD.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005840; C:ribosome; IDA:RGD.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISO:RGD.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 2.30.30.70; -; 1.
DR   InterPro; IPR036948; Ribosomal_L21_sf.
DR   InterPro; IPR001147; Ribosomal_L21e.
DR   InterPro; IPR018259; Ribosomal_L21e_CS.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR20981; PTHR20981; 1.
DR   Pfam; PF01157; Ribosomal_L21e; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   PROSITE; PS01171; RIBOSOMAL_L21E; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Direct protein sequencing; Endoplasmic reticulum;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..160
FT                   /note="60S ribosomal protein L21"
FT                   /id="PRO_0000149672"
FT   REGION          112..146
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   160 AA;  18466 MW;  68F265B18EAFB876 CRC64;
     MTNTKGKRRG TRYMFSRPFR KHGVVPLATY MRIYKKGDIV DIKGMGTVQK GMPHKCYHGK
     TGRVYNVTQH AVGIIVNKQV KGKILAKRIN VRIEHIKHSK SRDSFLKRVK ENDQKKKEAK
     EKGTWVQLNG QPAPPREAHF VRTNGKEPEL LEPIPYEFMA