ATPE_MYCS2
ID ATPE_MYCS2 Reviewed; 121 AA.
AC A0R1Z9; I7FR58;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=ATP synthase epsilon chain {ECO:0000255|HAMAP-Rule:MF_00530};
DE AltName: Full=ATP synthase F1 sector epsilon subunit {ECO:0000255|HAMAP-Rule:MF_00530};
DE AltName: Full=F-ATPase epsilon subunit {ECO:0000255|HAMAP-Rule:MF_00530};
GN Name=atpC {ECO:0000255|HAMAP-Rule:MF_00530};
GN OrderedLocusNames=MSMEG_4935, MSMEI_4808;
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155;
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155;
RX PubMed=17295914; DOI=10.1186/gb-2007-8-2-r20;
RA Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C.,
RA Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.;
RT "Interrupted coding sequences in Mycobacterium smegmatis: authentic
RT mutations or sequencing errors?";
RL Genome Biol. 8:R20.1-R20.9(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS], AND CLEAVAGE OF INITIATOR METHIONINE.
RC STRAIN=ATCC 700084 / mc(2)155;
RX PubMed=18955433; DOI=10.1101/gr.081901.108;
RA Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M.,
RA Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.;
RT "Ortho-proteogenomics: multiple proteomes investigation through orthology
RT and a new MS-based protocol.";
RL Genome Res. 19:128-135(2009).
CC -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC across the membrane. {ECO:0000255|HAMAP-Rule:MF_00530}.
CC -!- SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core
CC - and CF(0) - the membrane proton channel. CF(1) has five subunits:
CC alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main
CC subunits: a, b and c. {ECO:0000255|HAMAP-Rule:MF_00530}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00530};
CC Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00530}.
CC -!- SIMILARITY: Belongs to the ATPase epsilon chain family.
CC {ECO:0000255|HAMAP-Rule:MF_00530}.
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DR EMBL; CP000480; ABK70189.1; -; Genomic_DNA.
DR EMBL; CP001663; AFP41253.1; -; Genomic_DNA.
DR RefSeq; WP_011730202.1; NZ_SIJM01000067.1.
DR RefSeq; YP_889187.1; NC_008596.1.
DR PDB; 6FOC; X-ray; 4.00 A; H=1-121.
DR PDB; 6PI4; X-ray; 2.10 A; A=1-121.
DR PDB; 7JG5; EM; 3.40 A; H=1-121.
DR PDB; 7JG6; EM; 3.70 A; H=1-121.
DR PDB; 7JG7; EM; 3.50 A; H=1-121.
DR PDB; 7JG8; EM; 3.30 A; H=1-121.
DR PDB; 7JG9; EM; 3.40 A; H=1-121.
DR PDB; 7JGA; EM; 3.20 A; H=1-121.
DR PDB; 7NJK; EM; 2.52 A; H=1-121.
DR PDB; 7NJL; EM; 2.71 A; H=1-121.
DR PDB; 7NJM; EM; 2.84 A; H=1-121.
DR PDB; 7NJN; EM; 2.64 A; H=1-121.
DR PDB; 7NJO; EM; 2.92 A; H=1-121.
DR PDB; 7NJP; EM; 2.84 A; H=1-121.
DR PDB; 7NJQ; EM; 2.67 A; H=1-121.
DR PDB; 7NJR; EM; 2.56 A; H=1-121.
DR PDB; 7NJS; EM; 2.46 A; H=1-121.
DR PDB; 7NK9; EM; 2.90 A; H=1-121.
DR PDB; 7NKB; EM; 2.90 A; H=1-121.
DR PDB; 7NKK; EM; 3.60 A; H=1-121.
DR PDB; 7NKN; EM; 2.71 A; H=1-121.
DR PDB; 7NKP; EM; 4.06 A; H=1-121.
DR PDB; 7NL9; EM; 2.86 A; H=1-121.
DR PDBsum; 6FOC; -.
DR PDBsum; 6PI4; -.
DR PDBsum; 7JG5; -.
DR PDBsum; 7JG6; -.
DR PDBsum; 7JG7; -.
DR PDBsum; 7JG8; -.
DR PDBsum; 7JG9; -.
DR PDBsum; 7JGA; -.
DR PDBsum; 7NJK; -.
DR PDBsum; 7NJL; -.
DR PDBsum; 7NJM; -.
DR PDBsum; 7NJN; -.
DR PDBsum; 7NJO; -.
DR PDBsum; 7NJP; -.
DR PDBsum; 7NJQ; -.
DR PDBsum; 7NJR; -.
DR PDBsum; 7NJS; -.
DR PDBsum; 7NK9; -.
DR PDBsum; 7NKB; -.
DR PDBsum; 7NKK; -.
DR PDBsum; 7NKN; -.
DR PDBsum; 7NKP; -.
DR PDBsum; 7NL9; -.
DR AlphaFoldDB; A0R1Z9; -.
DR SMR; A0R1Z9; -.
DR STRING; 246196.MSMEI_4808; -.
DR PRIDE; A0R1Z9; -.
DR EnsemblBacteria; ABK70189; ABK70189; MSMEG_4935.
DR EnsemblBacteria; AFP41253; AFP41253; MSMEI_4808.
DR GeneID; 66736257; -.
DR KEGG; msg:MSMEI_4808; -.
DR KEGG; msm:MSMEG_4935; -.
DR PATRIC; fig|246196.19.peg.4814; -.
DR eggNOG; COG0355; Bacteria.
DR OMA; MGGFAEI; -.
DR OrthoDB; 1696893at2; -.
DR Proteomes; UP000000757; Chromosome.
DR Proteomes; UP000006158; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045261; C:proton-transporting ATP synthase complex, catalytic core F(1); IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-UniRule.
DR CDD; cd12152; F1-ATPase_delta; 1.
DR Gene3D; 2.60.15.10; -; 1.
DR HAMAP; MF_00530; ATP_synth_epsil_bac; 1.
DR InterPro; IPR001469; ATP_synth_F1_dsu/esu.
DR InterPro; IPR020546; ATP_synth_F1_dsu/esu_N.
DR InterPro; IPR036771; ATPsynth_dsu/esu_N.
DR Pfam; PF02823; ATP-synt_DE_N; 1.
DR SUPFAM; SSF51344; SSF51344; 1.
DR TIGRFAMs; TIGR01216; ATP_synt_epsi; 1.
PE 1: Evidence at protein level;
KW 3D-structure; ATP synthesis; Cell membrane; CF(1); Hydrogen ion transport;
KW Ion transport; Membrane; Reference proteome; Transport.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:18955433"
FT CHAIN 2..121
FT /note="ATP synthase epsilon chain"
FT /id="PRO_1000056506"
FT STRAND 4..8
FT /evidence="ECO:0007829|PDB:7NL9"
FT STRAND 21..27
FT /evidence="ECO:0007829|PDB:6PI4"
FT STRAND 30..34
FT /evidence="ECO:0007829|PDB:6PI4"
FT STRAND 41..45
FT /evidence="ECO:0007829|PDB:6PI4"
FT STRAND 50..54
FT /evidence="ECO:0007829|PDB:6PI4"
FT STRAND 56..58
FT /evidence="ECO:0007829|PDB:7NJR"
FT STRAND 61..67
FT /evidence="ECO:0007829|PDB:6PI4"
FT STRAND 69..72
FT /evidence="ECO:0007829|PDB:6PI4"
FT STRAND 77..80
FT /evidence="ECO:0007829|PDB:6PI4"
FT STRAND 82..86
FT /evidence="ECO:0007829|PDB:6PI4"
FT TURN 87..89
FT /evidence="ECO:0007829|PDB:6PI4"
FT HELIX 92..99
FT /evidence="ECO:0007829|PDB:6PI4"
FT STRAND 101..103
FT /evidence="ECO:0007829|PDB:7JGA"
FT HELIX 104..116
FT /evidence="ECO:0007829|PDB:6PI4"
SQ SEQUENCE 121 AA; 13265 MW; 58C440E79B0B2216 CRC64;
MADLNVEIVA VERELWSGPA TFVFTRTTAG EIGILPRHIP LVAQLVDDAM VRVEREGEDD
LRIAVDGGFL SVTEETVRIL VENAQFESEI DADAAKEDAA SDDERTAAWG RARLRALGQI
D
