RL22_SCHPO
ID RL22_SCHPO Reviewed; 117 AA.
AC Q09668; O13694; Q9UT13;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 11-JAN-2001, sequence version 3.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=60S ribosomal protein L22;
GN Name=rpl22; ORFNames=SPAC11E3.15, SPAP8A3.01;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 5-117.
RA Kawamukai M.;
RL Submitted (JUL-1996) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-49 AND SER-50, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL22 family.
CC {ECO:0000305}.
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DR EMBL; CU329670; CAB11194.2; -; Genomic_DNA.
DR EMBL; D86349; BAA13074.1; -; mRNA.
DR PIR; T37543; T37543.
DR RefSeq; NP_594940.1; NM_001020371.2.
DR AlphaFoldDB; Q09668; -.
DR SMR; Q09668; -.
DR BioGRID; 279457; 13.
DR IntAct; Q09668; 1.
DR STRING; 4896.SPAC11E3.15.1; -.
DR iPTMnet; Q09668; -.
DR SwissPalm; Q09668; -.
DR MaxQB; Q09668; -.
DR PaxDb; Q09668; -.
DR PRIDE; Q09668; -.
DR EnsemblFungi; SPAC11E3.15.1; SPAC11E3.15.1:pep; SPAC11E3.15.
DR GeneID; 2543021; -.
DR KEGG; spo:SPAC11E3.15; -.
DR PomBase; SPAC11E3.15; rpl22.
DR VEuPathDB; FungiDB:SPAC11E3.15; -.
DR eggNOG; KOG3434; Eukaryota.
DR HOGENOM; CLU_105624_0_0_1; -.
DR InParanoid; Q09668; -.
DR OMA; YQLRFYN; -.
DR PhylomeDB; Q09668; -.
DR Reactome; R-SPO-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-SPO-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-SPO-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-SPO-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-SPO-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-SPO-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:Q09668; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; ISO:PomBase.
DR GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; ISO:PomBase.
DR GO; GO:0002181; P:cytoplasmic translation; ISO:PomBase.
DR Gene3D; 3.30.1360.210; -; 1.
DR InterPro; IPR002671; Ribosomal_L22e.
DR InterPro; IPR038526; Ribosomal_L22e_sf.
DR PANTHER; PTHR10064; PTHR10064; 1.
DR Pfam; PF01776; Ribosomal_L22e; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..117
FT /note="60S ribosomal protein L22"
FT /id="PRO_0000215513"
FT MOD_RES 49
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 50
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT CONFLICT 117
FT /note="Q -> NKLAARNSCVFQN (in Ref. 2; BAA13074)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 117 AA; 13320 MW; 45312BAEE610B53F CRC64;
MVKKNTKVSN KYIIDATAAV NDKIFDVAAF EKYLIDRIKV DGKTGNLGSS VVVSREGSSK
IAVIAHIDFS GRYLKYLTKK FLKKHSLRDW LRVVSTKKGV YELRYYNVVV GNDEEEQ
