ID   RL22_THEKO              Reviewed;         156 AA.
AC   Q5JDH4;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=50S ribosomal protein L22 {ECO:0000255|HAMAP-Rule:MF_01331};
GN   Name=rpl22 {ECO:0000255|HAMAP-Rule:MF_01331}; OrderedLocusNames=TK1537;
OS   Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS   (Pyrococcus kodakaraensis (strain KOD1)).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-918 / JCM 12380 / KOD1;
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT   kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL   Genome Res. 15:352-363(2005).
CC   -!- FUNCTION: This protein binds specifically to 23S rRNA. It makes
CC       multiple contacts with different domains of the 23S rRNA in the
CC       assembled 50S subunit and ribosome. {ECO:0000255|HAMAP-Rule:MF_01331}.
CC   -!- FUNCTION: The globular domain of the protein is located near the
CC       polypeptide exit tunnel on the outside of the subunit, while an
CC       extended beta-hairpin is found that lines the wall of the exit tunnel
CC       in the center of the 70S ribosome. {ECO:0000255|HAMAP-Rule:MF_01331}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC       Rule:MF_01331}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL22 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01331}.
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DR   EMBL; AP006878; BAD85726.1; -; Genomic_DNA.
DR   RefSeq; WP_011250488.1; NC_006624.1.
DR   PDB; 6SKF; EM; 2.95 A; BV=1-156.
DR   PDB; 6SKG; EM; 2.65 A; BV=1-156.
DR   PDB; 6TH6; EM; 2.55 A; BV=1-156.
DR   PDBsum; 6SKF; -.
DR   PDBsum; 6SKG; -.
DR   PDBsum; 6TH6; -.
DR   AlphaFoldDB; Q5JDH4; -.
DR   SMR; Q5JDH4; -.
DR   STRING; 69014.TK1537; -.
DR   EnsemblBacteria; BAD85726; BAD85726; TK1537.
DR   GeneID; 3235324; -.
DR   KEGG; tko:TK1537; -.
DR   PATRIC; fig|69014.16.peg.1497; -.
DR   eggNOG; arCOG04098; Archaea.
DR   HOGENOM; CLU_083987_0_2_2; -.
DR   InParanoid; Q5JDH4; -.
DR   OMA; ANAEYKG; -.
DR   OrthoDB; 103467at2157; -.
DR   PhylomeDB; Q5JDH4; -.
DR   Proteomes; UP000000536; Chromosome.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR   CDD; cd00336; Ribosomal_L22; 1.
DR   Gene3D; 3.90.470.10; -; 1.
DR   HAMAP; MF_01331_A; Ribosomal_L22_A; 1.
DR   InterPro; IPR001063; Ribosomal_L22.
DR   InterPro; IPR018260; Ribosomal_L22/L17_CS.
DR   InterPro; IPR005721; Ribosomal_L22/L17_euk/arc.
DR   InterPro; IPR036394; Ribosomal_L22/L17_sf.
DR   PANTHER; PTHR11593; PTHR11593; 1.
DR   Pfam; PF00237; Ribosomal_L22; 1.
DR   SUPFAM; SSF54843; SSF54843; 1.
DR   TIGRFAMs; TIGR01038; uL22_arch_euk; 1.
DR   PROSITE; PS00464; RIBOSOMAL_L22; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   RNA-binding; rRNA-binding.
FT   CHAIN           1..156
FT                   /note="50S ribosomal protein L22"
FT                   /id="PRO_0000125286"
SQ   SEQUENCE   156 AA;  17802 MW;  9E7A0928E2F37E97 CRC64;
     MSRGRFSYSF QNFDPERMAR ASGRDLRISP KHSVELLREI RGMMLNDALR YLDDVIAKKR
     PVPMKRFNDS QGHKPGKGFG PGRYPVKVAK AVKKILLNAK NNAEQKGLDV DRLKIIHAAA
     HRGPVLRGYI PRAFGRATPF NEQTTHIEIV VEEIRR