ID   RL22_UREP2              Reviewed;         311 AA.
AC   B1AIM5;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=50S ribosomal protein L22;
GN   Name=rplV; OrderedLocusNames=UPA3_0244;
OS   Ureaplasma parvum serovar 3 (strain ATCC 27815 / 27 / NCTC 11736).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Ureaplasma.
OX   NCBI_TaxID=505682;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27815 / 27 / NCTC 11736;
RA   Methe B.A., Glass J., Waites K., Shrivastava S.;
RT   "Genome sequence of Ureaplasma parvum serovar 3.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein binds specifically to 23S rRNA; its binding is
CC       stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is
CC       important during the early stages of 50S assembly. It makes multiple
CC       contacts with different domains of the 23S rRNA in the assembled 50S
CC       subunit and ribosome (By similarity). {ECO:0000250}.
CC   -!- FUNCTION: The globular domain of the protein is located near the
CC       polypeptide exit tunnel on the outside of the subunit, while an
CC       extended beta-hairpin is found that lines the wall of the exit tunnel
CC       in the center of the 70S ribosome. {ECO:0000250}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL22 family.
CC       {ECO:0000305}.
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DR   EMBL; CP000942; ACA33068.1; -; Genomic_DNA.
DR   RefSeq; WP_006688968.1; NC_010503.1.
DR   AlphaFoldDB; B1AIM5; -.
DR   SMR; B1AIM5; -.
DR   EnsemblBacteria; ACA33068; ACA33068; UPA3_0244.
DR   GeneID; 29672595; -.
DR   KEGG; upa:UPA3_0244; -.
DR   HOGENOM; CLU_894135_0_0_14; -.
DR   OrthoDB; 1271556at2; -.
DR   Proteomes; UP000002162; Chromosome.
DR   GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd00336; Ribosomal_L22; 1.
DR   Gene3D; 3.90.470.10; -; 1.
DR   HAMAP; MF_01331_B; Ribosomal_L22_B; 1.
DR   InterPro; IPR001063; Ribosomal_L22.
DR   InterPro; IPR018260; Ribosomal_L22/L17_CS.
DR   InterPro; IPR036394; Ribosomal_L22/L17_sf.
DR   InterPro; IPR005727; Ribosomal_L22_bac/chlpt-type.
DR   PANTHER; PTHR13501; PTHR13501; 1.
DR   Pfam; PF00237; Ribosomal_L22; 1.
DR   SUPFAM; SSF54843; SSF54843; 1.
DR   TIGRFAMs; TIGR01044; rplV_bact; 1.
DR   PROSITE; PS00464; RIBOSOMAL_L22; 1.
PE   3: Inferred from homology;
KW   Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding.
FT   CHAIN           1..311
FT                   /note="50S ribosomal protein L22"
FT                   /id="PRO_0000354537"
SQ   SEQUENCE   311 AA;  35389 MW;  803179960C35D871 CRC64;
     MTNKVIQRNI HISHRKASLV IDLVRNKPVH EAIRILSNTP KKFAPIVLKL LNSAISNVQH
     NSKDMDPSKL YIYKIVANQG PTMKRTLPRA KGSADQLFKR TTHLEIVLSD DVNEREKELA
     AIKAKKSKKP LAVEPIAKVE TKKVAKPSKV EIKPVEKDEN VDPELLKREQ QVLKVVEKTA
     SQKEEETTET IMISTSPKNA QVLFDDLEKN VIFYKTTPIN KVLRVLVYVT SPTKKVVGEF
     DLESVEIGAI SSIWRKYSKQ SVISKKEYDA YYEGKDKAHA LVSKKAYKYR NPKDLSEYNM
     TKGPSGFQYL K