RL23_BACSU
ID RL23_BACSU Reviewed; 95 AA.
AC P42924;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 2.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=50S ribosomal protein L23 {ECO:0000255|HAMAP-Rule:MF_01369};
GN Name=rplW {ECO:0000255|HAMAP-Rule:MF_01369}; OrderedLocusNames=BSU01180;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=SG38;
RX PubMed=9371452; DOI=10.1128/jb.179.22.7046-7054.1997;
RA Li X., Lindahl L., Sha Y., Zengel J.M.;
RT "Analysis of the Bacillus subtilis S10 ribosomal protein gene cluster
RT identifies two promoters that may be responsible for transcription of the
RT entire 15-kilobase S10-spc-alpha cluster.";
RL J. Bacteriol. 179:7046-7054(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=8969501; DOI=10.1099/13500872-142-11-3039;
RA Yasumoto K., Liu H., Jeong S.M., Ohashi Y., Kakinuma S., Tanaka K.,
RA Kawamura F., Yoshikawa H., Takahashi H.;
RT "Sequence analysis of a 50 kb region between spo0H and rrnH on the Bacillus
RT subtilis chromosome.";
RL Microbiology 142:3039-3046(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [4]
RP SEQUENCE REVISION TO 24 AND 39.
RX PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT 168 reference genome a decade later.";
RL Microbiology 155:1758-1775(2009).
RN [5] {ECO:0007744|PDB:6HA1, ECO:0007744|PDB:6HA8}
RP STRUCTURE BY ELECTRON MICROSCOPY (3.10 ANGSTROMS) OF 1-95 WITH AND WITHOUT
RP VIRGINIAMYCIN M, AND SUBUNIT.
RX PubMed=30126986; DOI=10.1073/pnas.1808535115;
RA Crowe-McAuliffe C., Graf M., Huter P., Takada H., Abdelshahid M.,
RA Novacek J., Murina V., Atkinson G.C., Hauryliuk V., Wilson D.N.;
RT "Structural basis for antibiotic resistance mediated by the Bacillus
RT subtilis ABCF ATPase VmlR.";
RL Proc. Natl. Acad. Sci. U.S.A. 115:8978-8983(2018).
CC -!- FUNCTION: One of the early assembly proteins it binds 23S rRNA. One of
CC the proteins that surrounds the polypeptide exit tunnel on the outside
CC of the ribosome. Forms the main docking site for trigger factor binding
CC to the ribosome. {ECO:0000255|HAMAP-Rule:MF_01369}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit (PubMed:30126986). Contacts
CC protein L29, and trigger factor when it is bound to the ribosome (By
CC similarity). {ECO:0000255|HAMAP-Rule:MF_01369,
CC ECO:0000269|PubMed:30126986}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL23 family.
CC {ECO:0000255|HAMAP-Rule:MF_01369}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U43929; AAC45958.1; -; Genomic_DNA.
DR EMBL; D50302; BAA08833.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB11894.2; -; Genomic_DNA.
DR PIR; A69697; A69697.
DR RefSeq; NP_387999.2; NC_000964.3.
DR RefSeq; WP_003156467.1; NZ_JNCM01000029.1.
DR PDB; 3J3V; EM; 13.30 A; T=1-95.
DR PDB; 3J3W; EM; 10.70 A; T=1-95.
DR PDB; 3J9W; EM; 3.90 A; BW=1-95.
DR PDB; 5NJT; EM; 3.80 A; m=1-93.
DR PDB; 6HA1; EM; 3.10 A; T=1-95.
DR PDB; 6HA8; EM; 3.50 A; T=1-95.
DR PDB; 6HTQ; EM; 4.50 A; T=2-91.
DR PDB; 6PPF; EM; 3.40 A; T=1-95.
DR PDB; 6PPK; EM; 4.40 A; T=1-95.
DR PDB; 6PVK; EM; 3.40 A; T=1-95.
DR PDB; 6TNN; EM; 3.07 A; m=1-95.
DR PDB; 6TPQ; EM; 3.07 A; m=1-95.
DR PDB; 7AQC; EM; 2.99 A; h=1-95.
DR PDB; 7AQD; EM; 3.10 A; h=1-95.
DR PDB; 7AS8; EM; 2.90 A; X=1-95.
DR PDB; 7AS9; EM; 3.50 A; X=1-95.
DR PDB; 7O5B; EM; 3.33 A; s=1-95.
DR PDB; 7OPE; EM; 3.20 A; X=1-95.
DR PDB; 7QV1; EM; 3.50 A; T=1-95.
DR PDB; 7QV2; EM; 3.50 A; T=1-95.
DR PDB; 7QV3; EM; 5.14 A; T=1-95.
DR PDBsum; 3J3V; -.
DR PDBsum; 3J3W; -.
DR PDBsum; 3J9W; -.
DR PDBsum; 5NJT; -.
DR PDBsum; 6HA1; -.
DR PDBsum; 6HA8; -.
DR PDBsum; 6HTQ; -.
DR PDBsum; 6PPF; -.
DR PDBsum; 6PPK; -.
DR PDBsum; 6PVK; -.
DR PDBsum; 6TNN; -.
DR PDBsum; 6TPQ; -.
DR PDBsum; 7AQC; -.
DR PDBsum; 7AQD; -.
DR PDBsum; 7AS8; -.
DR PDBsum; 7AS9; -.
DR PDBsum; 7O5B; -.
DR PDBsum; 7OPE; -.
DR PDBsum; 7QV1; -.
DR PDBsum; 7QV2; -.
DR PDBsum; 7QV3; -.
DR AlphaFoldDB; P42924; -.
DR SMR; P42924; -.
DR IntAct; P42924; 3.
DR STRING; 224308.BSU01180; -.
DR jPOST; P42924; -.
DR PaxDb; P42924; -.
DR PRIDE; P42924; -.
DR EnsemblBacteria; CAB11894; CAB11894; BSU_01180.
DR GeneID; 66327861; -.
DR GeneID; 936820; -.
DR KEGG; bsu:BSU01180; -.
DR PATRIC; fig|224308.179.peg.121; -.
DR eggNOG; COG0089; Bacteria.
DR InParanoid; P42924; -.
DR OMA; FEVDHRA; -.
DR PhylomeDB; P42924; -.
DR BioCyc; BSUB:BSU01180-MON; -.
DR PRO; PR:P42924; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0000027; P:ribosomal large subunit assembly; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.330; -; 1.
DR HAMAP; MF_01369_B; Ribosomal_L23_B; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR012678; Ribosomal_L23/L15e_core_dom_sf.
DR InterPro; IPR001014; Ribosomal_L23/L25_CS.
DR InterPro; IPR013025; Ribosomal_L25/23.
DR PANTHER; PTHR11620; PTHR11620; 1.
DR Pfam; PF00276; Ribosomal_L23; 1.
DR SUPFAM; SSF54189; SSF54189; 1.
DR PROSITE; PS00050; RIBOSOMAL_L23; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..95
FT /note="50S ribosomal protein L23"
FT /id="PRO_0000129398"
FT CONFLICT 24
FT /note="K -> E (in Ref. 1; AAC45958 and 2; BAA08833)"
FT /evidence="ECO:0000305"
FT CONFLICT 39
FT /note="V -> A (in Ref. 1; AAC45958 and 2; BAA08833)"
FT /evidence="ECO:0000305"
FT HELIX 4..7
FT /evidence="ECO:0007829|PDB:7AS8"
FT STRAND 8..10
FT /evidence="ECO:0007829|PDB:7AS8"
FT HELIX 15..22
FT /evidence="ECO:0007829|PDB:7AS8"
FT STRAND 25..30
FT /evidence="ECO:0007829|PDB:7AS8"
FT HELIX 36..47
FT /evidence="ECO:0007829|PDB:7AS8"
FT STRAND 52..56
FT /evidence="ECO:0007829|PDB:7AS8"
FT STRAND 63..66
FT /evidence="ECO:0007829|PDB:7AQC"
FT STRAND 69..72
FT /evidence="ECO:0007829|PDB:7AQC"
FT STRAND 76..82
FT /evidence="ECO:0007829|PDB:7AS8"
FT STRAND 85..87
FT /evidence="ECO:0007829|PDB:6TNN"
SQ SEQUENCE 95 AA; 10956 MW; 54272FBD14393AD6 CRC64;
MKDPRDVLKR PVITERSADL MTEKKYTFEV DVRANKTEVK DAVESIFGVK VDKVNIMNYK
GKSKRVGRYT GMTSRRRKAI VKLTADSKEI EIFEA
