ID   RL23_BOVIN              Reviewed;         140 AA.
AC   Q3T057; A6QLM2;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 2.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=60S ribosomal protein L23;
GN   Name=RPL23;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus, and Hereford; TISSUE=Ileum, and Testis;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:P62829}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P62829}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P62829}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL14 family.
CC       {ECO:0000305}.
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DR   EMBL; BC102556; AAI02557.1; -; mRNA.
DR   EMBL; BC148014; AAI48015.1; -; mRNA.
DR   RefSeq; NP_001030186.1; NM_001035014.2.
DR   AlphaFoldDB; Q3T057; -.
DR   SMR; Q3T057; -.
DR   STRING; 9913.ENSBTAP00000004190; -.
DR   PaxDb; Q3T057; -.
DR   PeptideAtlas; Q3T057; -.
DR   PRIDE; Q3T057; -.
DR   Ensembl; ENSBTAT00000004190; ENSBTAP00000004190; ENSBTAG00000003229.
DR   GeneID; 504876; -.
DR   KEGG; bta:504876; -.
DR   CTD; 9349; -.
DR   VEuPathDB; HostDB:ENSBTAG00000003229; -.
DR   VGNC; VGNC:55867; RPL23.
DR   eggNOG; KOG0901; Eukaryota.
DR   GeneTree; ENSGT00390000004690; -.
DR   HOGENOM; CLU_095071_3_0_1; -.
DR   InParanoid; Q3T057; -.
DR   OMA; AKEVLCI; -.
DR   OrthoDB; 1374830at2759; -.
DR   TreeFam; TF300913; -.
DR   Reactome; R-BTA-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-BTA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-BTA-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-BTA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-BTA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   Proteomes; UP000009136; Chromosome 19.
DR   Bgee; ENSBTAG00000003229; Expressed in theca cell and 105 other tissues.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0070180; F:large ribosomal subunit rRNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0001223; F:transcription coactivator binding; IEA:Ensembl.
DR   GO; GO:1990948; F:ubiquitin ligase inhibitor activity; IEA:Ensembl.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:Ensembl.
DR   GO; GO:0072717; P:cellular response to actinomycin D; IEA:Ensembl.
DR   GO; GO:0070314; P:G1 to G0 transition; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:2000059; P:negative regulation of ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell population proliferation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:1901798; P:positive regulation of signal transduction by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR   GO; GO:0032986; P:protein-DNA complex disassembly; IEA:Ensembl.
DR   GO; GO:1903450; P:regulation of G1 to G0 transition; IEA:Ensembl.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 2.40.150.20; -; 1.
DR   HAMAP; MF_01367; Ribosomal_L14; 1.
DR   InterPro; IPR036853; Ribosomal_L14_sf.
DR   InterPro; IPR000218; Ribosomal_L14P.
DR   InterPro; IPR019972; Ribosomal_L14P_CS.
DR   PANTHER; PTHR11761; PTHR11761; 1.
DR   Pfam; PF00238; Ribosomal_L14; 1.
DR   SMART; SM01374; Ribosomal_L14; 1.
DR   SUPFAM; SSF50193; SSF50193; 1.
DR   PROSITE; PS00049; RIBOSOMAL_L14; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Phosphoprotein; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein.
FT   CHAIN           1..140
FT                   /note="60S ribosomal protein L23"
FT                   /id="PRO_0000240138"
FT   MOD_RES         17
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P62829"
FT   MOD_RES         38
FT                   /note="Phosphotyrosine"
FT                   /evidence="ECO:0000250|UniProtKB:P62829"
FT   CONFLICT        4
FT                   /note="R -> L (in Ref. 1; AAI02557)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   140 AA;  14865 MW;  807E14139B2EB0B5 CRC64;
     MSKRGRGGSS GAKFRISLGL PVGAVINCAD NTGAKNLYII SVKGIKGRLN RLPAAGVGDM
     VMATVKKGKP ELRKKVHPAV VIRQRKSYRR KDGVFLYFED NAGVIVNNKG EMKGSAITGP
     VAKECADLWP RIASNAGSIA