RL23_PIG
ID RL23_PIG Reviewed; 140 AA.
AC P62831; A1XQU4; P23131; P24048; Q29246;
DT 16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=60S ribosomal protein L23;
DE AltName: Full=Ribosomal protein L17;
GN Name=RPL23;
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Small intestine;
RX PubMed=8672129; DOI=10.1007/s003359900153;
RA Winteroe A.K., Fredholm M., Davies W.;
RT "Evaluation and characterization of a porcine small intestine cDNA library:
RT analysis of 839 clones.";
RL Mamm. Genome 7:509-517(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Longissimus dorsi muscle;
RA Cai G., Chen Y., Wang C., Li J., Peng G., Zhang H.;
RT "Generation and analysis of cDNA sequences derived from a porcine skeletal
RT muscle library.";
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC large ribonucleoprotein complex responsible for the synthesis of
CC proteins in the cell. {ECO:0000250|UniProtKB:P62829}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:P62829}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P62829}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL14 family.
CC {ECO:0000305}.
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DR EMBL; F14853; CAA23296.1; -; mRNA.
DR EMBL; DQ629166; ABK55650.1; -; mRNA.
DR RefSeq; NP_001123427.1; NM_001129955.1.
DR PDB; 3J7O; EM; 3.40 A; V=1-140.
DR PDB; 3J7P; EM; 3.50 A; V=1-140.
DR PDB; 3J7Q; EM; 3.40 A; V=1-140.
DR PDB; 3J7R; EM; 3.90 A; V=1-140.
DR PDBsum; 3J7O; -.
DR PDBsum; 3J7P; -.
DR PDBsum; 3J7Q; -.
DR PDBsum; 3J7R; -.
DR AlphaFoldDB; P62831; -.
DR SMR; P62831; -.
DR STRING; 9823.ENSSSCP00000023781; -.
DR PaxDb; P62831; -.
DR PeptideAtlas; P62831; -.
DR PRIDE; P62831; -.
DR Ensembl; ENSSSCT00000051843; ENSSSCP00000039109; ENSSSCG00000038880.
DR Ensembl; ENSSSCT00005033514; ENSSSCP00005020452; ENSSSCG00005021234.
DR Ensembl; ENSSSCT00005033535; ENSSSCP00005020465; ENSSSCG00005021234.
DR Ensembl; ENSSSCT00005033558; ENSSSCP00005020479; ENSSSCG00005021234.
DR Ensembl; ENSSSCT00005033587; ENSSSCP00005020497; ENSSSCG00005021234.
DR Ensembl; ENSSSCT00005033630; ENSSSCP00005020528; ENSSSCG00005021234.
DR Ensembl; ENSSSCT00015046494; ENSSSCP00015018392; ENSSSCG00015034602.
DR Ensembl; ENSSSCT00030077118; ENSSSCP00030035210; ENSSSCG00030055317.
DR Ensembl; ENSSSCT00030077140; ENSSSCP00030035224; ENSSSCG00030055317.
DR Ensembl; ENSSSCT00035003058; ENSSSCP00035001053; ENSSSCG00035002443.
DR Ensembl; ENSSSCT00035024755; ENSSSCP00035009309; ENSSSCG00035019140.
DR Ensembl; ENSSSCT00040053952; ENSSSCP00040022470; ENSSSCG00040040092.
DR Ensembl; ENSSSCT00045044853; ENSSSCP00045031120; ENSSSCG00045026297.
DR Ensembl; ENSSSCT00050080584; ENSSSCP00050034596; ENSSSCG00050059140.
DR Ensembl; ENSSSCT00055008467; ENSSSCP00055006694; ENSSSCG00055004278.
DR Ensembl; ENSSSCT00065054815; ENSSSCP00065023823; ENSSSCG00065040079.
DR Ensembl; ENSSSCT00070034645; ENSSSCP00070028941; ENSSSCG00070017546.
DR GeneID; 414398; -.
DR KEGG; ssc:414398; -.
DR CTD; 9349; -.
DR eggNOG; KOG0901; Eukaryota.
DR GeneTree; ENSGT00390000004690; -.
DR HOGENOM; CLU_095071_3_0_1; -.
DR InParanoid; P62831; -.
DR OMA; AKEVLCI; -.
DR OrthoDB; 1374830at2759; -.
DR TreeFam; TF300913; -.
DR Reactome; R-SSC-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-SSC-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-SSC-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-SSC-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-SSC-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-SSC-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR Proteomes; UP000008227; Chromosome 12.
DR Proteomes; UP000314985; Chromosome 12.
DR Bgee; ENSSSCG00000038880; Expressed in forelimb bud and 44 other tissues.
DR Genevisible; P62831; SS.
DR GO; GO:0098556; C:cytoplasmic side of rough endoplasmic reticulum membrane; IDA:UniProtKB.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0015934; C:large ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0070180; F:large ribosomal subunit rRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 2.40.150.20; -; 1.
DR HAMAP; MF_01367; Ribosomal_L14; 1.
DR InterPro; IPR036853; Ribosomal_L14_sf.
DR InterPro; IPR000218; Ribosomal_L14P.
DR InterPro; IPR019972; Ribosomal_L14P_CS.
DR PANTHER; PTHR11761; PTHR11761; 1.
DR Pfam; PF00238; Ribosomal_L14; 1.
DR SMART; SM01374; Ribosomal_L14; 1.
DR SUPFAM; SSF50193; SSF50193; 1.
DR PROSITE; PS00049; RIBOSOMAL_L14; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; Phosphoprotein; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..140
FT /note="60S ribosomal protein L23"
FT /id="PRO_0000128614"
FT MOD_RES 17
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P62829"
FT MOD_RES 38
FT /note="Phosphotyrosine"
FT /evidence="ECO:0000250|UniProtKB:P62829"
SQ SEQUENCE 140 AA; 14865 MW; 807E14139B2EB0B5 CRC64;
MSKRGRGGSS GAKFRISLGL PVGAVINCAD NTGAKNLYII SVKGIKGRLN RLPAAGVGDM
VMATVKKGKP ELRKKVHPAV VIRQRKSYRR KDGVFLYFED NAGVIVNNKG EMKGSAITGP
VAKECADLWP RIASNAGSIA
