ID   RL25A_SCHPO             Reviewed;         141 AA.
AC   Q10330; Q9URI6;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 141.
DE   RecName: Full=60S ribosomal protein L25-A;
GN   Name=rpl2501; Synonyms=rpl25a; ORFNames=SPBC106.18;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 100-141.
RC   STRAIN=972 / ATCC 24843;
RA   Jang Y.-J., Yoo H.-S.;
RL   Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-68 AND SER-70, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- FUNCTION: This protein binds to a specific region on the 26S rRNA.
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: There are two genes for L25 in S.pombe.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL23 family.
CC       {ECO:0000305}.
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DR   EMBL; CU329671; CAB53734.1; -; Genomic_DNA.
DR   EMBL; U97386; AAB63878.1; -; mRNA.
DR   PIR; T37983; T37983.
DR   RefSeq; NP_595167.1; NM_001021076.2.
DR   AlphaFoldDB; Q10330; -.
DR   SMR; Q10330; -.
DR   BioGRID; 276254; 10.
DR   IntAct; Q10330; 2.
DR   STRING; 4896.SPBC106.18.1; -.
DR   iPTMnet; Q10330; -.
DR   MaxQB; Q10330; -.
DR   PaxDb; Q10330; -.
DR   PRIDE; Q10330; -.
DR   EnsemblFungi; SPBC106.18.1; SPBC106.18.1:pep; SPBC106.18.
DR   GeneID; 2539701; -.
DR   KEGG; spo:SPBC106.18; -.
DR   PomBase; SPBC106.18; rpl2501.
DR   VEuPathDB; FungiDB:SPBC106.18; -.
DR   eggNOG; KOG1751; Eukaryota.
DR   HOGENOM; CLU_037562_0_1_1; -.
DR   InParanoid; Q10330; -.
DR   OMA; VHFRRPV; -.
DR   PhylomeDB; Q10330; -.
DR   PRO; PR:Q10330; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; ISO:PomBase.
DR   GO; GO:0019843; F:rRNA binding; ISO:PomBase.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISO:PomBase.
DR   GO; GO:0002181; P:cytoplasmic translation; ISO:PomBase.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; ISO:PomBase.
DR   Gene3D; 3.30.70.330; -; 1.
DR   HAMAP; MF_01369_A; Ribosomal_L23_A; 1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR012678; Ribosomal_L23/L15e_core_dom_sf.
DR   InterPro; IPR001014; Ribosomal_L23/L25_CS.
DR   InterPro; IPR005633; Ribosomal_L23/L25_N.
DR   InterPro; IPR013025; Ribosomal_L25/23.
DR   PANTHER; PTHR11620; PTHR11620; 1.
DR   Pfam; PF00276; Ribosomal_L23; 1.
DR   Pfam; PF03939; Ribosomal_L23eN; 1.
DR   SUPFAM; SSF54189; SSF54189; 1.
DR   PROSITE; PS00050; RIBOSOMAL_L23; 1.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   RNA-binding; rRNA-binding.
FT   CHAIN           1..141
FT                   /note="60S ribosomal protein L25-A"
FT                   /id="PRO_0000129481"
FT   MOD_RES         68
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   MOD_RES         70
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
SQ   SEQUENCE   141 AA;  15836 MW;  1982D16DB7CF5807 CRC64;
     MSVAKAKGAQ KTVQKGIHNK VAKKVRTSTT FRRPKTLQLS RKPKYARKSV AHAPRLDEYK
     IIVNPINSES AMKKIEDDNT LVFHVHLKAN KFTIKEAVRK LYSVEPVKIN TLIRPNGTKK
     AFVKLSADAD ALDVANRIGF L