RL25_THET2
ID RL25_THET2 Reviewed; 206 AA.
AC Q72IA7;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 110.
DE RecName: Full=50S ribosomal protein L25 {ECO:0000255|HAMAP-Rule:MF_01334};
DE AltName: Full=General stress protein CTC {ECO:0000255|HAMAP-Rule:MF_01334};
GN Name=rplY {ECO:0000255|HAMAP-Rule:MF_01334};
GN Synonyms=ctc {ECO:0000255|HAMAP-Rule:MF_01334}; OrderedLocusNames=TT_C1225;
OS Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27).
OC Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=262724;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-163 / DSM 7039 / HB27;
RX PubMed=15064768; DOI=10.1038/nbt956;
RA Henne A., Brueggemann H., Raasch C., Wiezer A., Hartsch T., Liesegang H.,
RA Johann A., Lienard T., Gohl O., Martinez-Arias R., Jacobi C.,
RA Starkuviene V., Schlenczeck S., Dencker S., Huber R., Klenk H.-P.,
RA Kramer W., Merkl R., Gottschalk G., Fritz H.-J.;
RT "The genome sequence of the extreme thermophile Thermus thermophilus.";
RL Nat. Biotechnol. 22:547-553(2004).
CC -!- FUNCTION: This is one of the proteins that binds to the 5S RNA in the
CC ribosome where it forms part of the central protuberance.
CC {ECO:0000255|HAMAP-Rule:MF_01334}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit; part of the 5S
CC rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA
CC independently of L5 and L18. {ECO:0000255|HAMAP-Rule:MF_01334}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL25 family. CTC
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_01334}.
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DR EMBL; AE017221; AAS81567.1; -; Genomic_DNA.
DR RefSeq; WP_011173631.1; NC_005835.1.
DR PDB; 4V4I; X-ray; 3.71 A; T=1-206.
DR PDB; 4V4J; X-ray; 3.83 A; T=1-206.
DR PDB; 4V63; X-ray; 3.21 A; BZ/DZ=1-206.
DR PDB; 4V67; X-ray; 3.00 A; BZ/DZ=1-206.
DR PDB; 4V7P; X-ray; 3.62 A; BV/CV=1-206.
DR PDB; 4V83; X-ray; 3.50 A; BV/DV=3-190.
DR PDB; 4V84; X-ray; 3.40 A; BV/DV=3-190.
DR PDB; 4V9J; X-ray; 3.86 A; BZ/DZ=3-187.
DR PDB; 4V9K; X-ray; 3.50 A; BZ/DZ=3-187.
DR PDB; 4V9L; X-ray; 3.50 A; BZ/DZ=3-187.
DR PDB; 4V9M; X-ray; 4.00 A; BZ/DZ=3-187.
DR PDB; 4V9N; X-ray; 3.40 A; BZ/DZ=3-189.
DR PDB; 4V9Q; X-ray; 3.40 A; AV/CV=3-189.
DR PDB; 4W29; X-ray; 3.80 A; BZ/DZ=3-187.
DR PDB; 4XEJ; X-ray; 3.80 A; AL25/BL25=3-189.
DR PDB; 5J4D; X-ray; 3.10 A; BC/W=1-206.
DR PDBsum; 4V4I; -.
DR PDBsum; 4V4J; -.
DR PDBsum; 4V63; -.
DR PDBsum; 4V67; -.
DR PDBsum; 4V7P; -.
DR PDBsum; 4V83; -.
DR PDBsum; 4V84; -.
DR PDBsum; 4V9J; -.
DR PDBsum; 4V9K; -.
DR PDBsum; 4V9L; -.
DR PDBsum; 4V9M; -.
DR PDBsum; 4V9N; -.
DR PDBsum; 4V9Q; -.
DR PDBsum; 4W29; -.
DR PDBsum; 4XEJ; -.
DR PDBsum; 5J4D; -.
DR AlphaFoldDB; Q72IA7; -.
DR SMR; Q72IA7; -.
DR IntAct; Q72IA7; 4.
DR STRING; 262724.TT_C1225; -.
DR EnsemblBacteria; AAS81567; AAS81567; TT_C1225.
DR GeneID; 3169859; -.
DR KEGG; tth:TT_C1225; -.
DR eggNOG; COG1825; Bacteria.
DR HOGENOM; CLU_075939_2_0_0; -.
DR OMA; HVDFYEV; -.
DR OrthoDB; 1673077at2; -.
DR EvolutionaryTrace; Q72IA7; -.
DR Proteomes; UP000000592; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0008097; F:5S rRNA binding; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd00495; Ribosomal_L25_TL5_CTC; 1.
DR Gene3D; 2.170.120.20; -; 1.
DR Gene3D; 2.40.240.10; -; 1.
DR HAMAP; MF_01334; Ribosomal_L25_CTC; 1.
DR InterPro; IPR020056; Rbsml_L25/Gln-tRNA_synth_N.
DR InterPro; IPR029751; Ribosomal_L25.
DR InterPro; IPR011035; Ribosomal_L25/Gln-tRNA_synth.
DR InterPro; IPR020057; Ribosomal_L25_b-dom.
DR InterPro; IPR037121; Ribosomal_L25_C.
DR InterPro; IPR001021; Ribosomal_L25_long.
DR Pfam; PF01386; Ribosomal_L25p; 1.
DR Pfam; PF14693; Ribosomal_TL5_C; 1.
DR SUPFAM; SSF50715; SSF50715; 1.
DR TIGRFAMs; TIGR00731; bL25_bact_ctc; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW rRNA-binding.
FT CHAIN 1..206
FT /note="50S ribosomal protein L25"
FT /id="PRO_0000181607"
FT REGION 184..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 4..6
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 11..13
FT /evidence="ECO:0007829|PDB:4V84"
FT HELIX 15..21
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 23..29
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 34..40
FT /evidence="ECO:0007829|PDB:4V67"
FT HELIX 41..51
FT /evidence="ECO:0007829|PDB:4V67"
FT TURN 52..54
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 57..60
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 66..76
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 78..80
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 83..90
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 96..101
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 102..105
FT /evidence="ECO:0007829|PDB:4V9L"
FT HELIX 109..112
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 116..118
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 122..128
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 137..139
FT /evidence="ECO:0007829|PDB:4V63"
FT STRAND 149..151
FT /evidence="ECO:0007829|PDB:4V67"
FT HELIX 152..154
FT /evidence="ECO:0007829|PDB:4V63"
FT STRAND 162..165
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 170..175
FT /evidence="ECO:0007829|PDB:4V67"
FT HELIX 181..188
FT /evidence="ECO:0007829|PDB:4V67"
SQ SEQUENCE 206 AA; 23205 MW; ACC20EC1279181CD CRC64;
MEYRLKAYYR EGEKPSALRR AGKLPGVMYN RHLNRKVYVD LVEFDKVFRQ ASIHHVIVLE
LPDGQSLPTL VRQVNLDKRR RRPEHVDFFV LSDEPVEMYV PLRFVGTPAG VRAGGVLQEI
HRDILVKVSP RNIPEFIEVD VSGLEIGDSL HASDLKLPPG VELAVSPEET IAAVVPPEDV
EKLAEEAAAE VAEPEVIKKG KEEEEE
