RL26_CAEEL
ID RL26_CAEEL Reviewed; 142 AA.
AC Q19869; Q8I121; Q9U3H7;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=60S ribosomal protein L26;
GN Name=rpl-26; ORFNames=F28C6.7;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=a;
CC IsoId=Q19869-1; Sequence=Displayed;
CC Name=b;
CC IsoId=Q19869-2; Sequence=VSP_020728;
CC Name=c;
CC IsoId=Q19869-3; Sequence=VSP_020727;
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL24 family.
CC {ECO:0000305}.
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DR EMBL; Z68315; CAA92674.1; -; Genomic_DNA.
DR EMBL; Z68315; CAA92678.1; -; Genomic_DNA.
DR EMBL; Z68315; CAD59149.1; -; Genomic_DNA.
DR PIR; T21486; T21486.
DR PIR; T21490; T21490.
DR RefSeq; NP_495823.1; NM_063422.4. [Q19869-1]
DR RefSeq; NP_495824.1; NM_063423.6.
DR RefSeq; NP_871965.1; NM_182165.5. [Q19869-3]
DR AlphaFoldDB; Q19869; -.
DR SMR; Q19869; -.
DR BioGRID; 39707; 87.
DR STRING; 6239.F28C6.7a.3; -.
DR iPTMnet; Q19869; -.
DR EPD; Q19869; -.
DR PaxDb; Q19869; -.
DR PeptideAtlas; Q19869; -.
DR EnsemblMetazoa; F28C6.7a.1; F28C6.7a.1; WBGene00004440. [Q19869-1]
DR EnsemblMetazoa; F28C6.7b.1; F28C6.7b.1; WBGene00004440. [Q19869-2]
DR EnsemblMetazoa; F28C6.7b.2; F28C6.7b.2; WBGene00004440. [Q19869-2]
DR EnsemblMetazoa; F28C6.7c.1; F28C6.7c.1; WBGene00004440. [Q19869-3]
DR GeneID; 174379; -.
DR KEGG; cel:CELE_F28C6.7; -.
DR UCSC; F28C6.7a.1; c. elegans. [Q19869-1]
DR CTD; 174379; -.
DR WormBase; F28C6.7a; CE03278; WBGene00004440; rpl-26. [Q19869-1]
DR WormBase; F28C6.7b; CE20731; WBGene00004440; rpl-26. [Q19869-2]
DR WormBase; F28C6.7c; CE32883; WBGene00004440; rpl-26. [Q19869-3]
DR eggNOG; KOG3401; Eukaryota.
DR GeneTree; ENSGT00390000014165; -.
DR HOGENOM; CLU_093240_0_0_1; -.
DR InParanoid; Q19869; -.
DR OMA; VRIMRGD; -.
DR OrthoDB; 1488916at2759; -.
DR PhylomeDB; Q19869; -.
DR Reactome; R-CEL-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-CEL-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-CEL-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-CEL-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-CEL-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-CEL-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:Q19869; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00004440; Expressed in larva and 4 other tissues.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR CDD; cd06089; KOW_RPL26; 1.
DR Gene3D; 2.30.30.30; -; 1.
DR HAMAP; MF_01326_A; Ribosomal_L24_A; 1.
DR InterPro; IPR005824; KOW.
DR InterPro; IPR041988; KOW_RPL26/RPL24.
DR InterPro; IPR014722; Rib_L2_dom2.
DR InterPro; IPR005825; Ribosomal_L24/26_CS.
DR InterPro; IPR005756; Ribosomal_L26/L24P_euk/arc.
DR InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR PANTHER; PTHR11143; PTHR11143; 1.
DR Pfam; PF00467; KOW; 1.
DR Pfam; PF16906; Ribosomal_L26; 1.
DR SMART; SM00739; KOW; 1.
DR SUPFAM; SSF50104; SSF50104; 1.
DR TIGRFAMs; TIGR01080; rplX_A_E; 1.
DR PROSITE; PS01108; RIBOSOMAL_L24; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein.
FT CHAIN 1..142
FT /note="60S ribosomal protein L26"
FT /id="PRO_0000130795"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 104..142
FT /note="AITKLKLDKDRRALVERKAAGRSRVTGILKGKHTDETVN -> RFV (in
FT isoform b)"
FT /evidence="ECO:0000305"
FT /id="VSP_020728"
FT VAR_SEQ 104..142
FT /note="AITKLKLDKDRRALVERKAAGRSRVTGILKGKHTDETVN -> RSLSPS
FT (in isoform c)"
FT /evidence="ECO:0000305"
FT /id="VSP_020727"
SQ SEQUENCE 142 AA; 16075 MW; B496362F0BFEC354 CRC64;
MKVNPFVSSD SGKSRKAHFN APSHERRRIM SAPLTKELRT KHGIRAIPIR TDDEVVVMRG
RHKGNTGRVL RCYRKKFVIH IDKITREKAN GSTVHIGIHP SKVAITKLKL DKDRRALVER
KAAGRSRVTG ILKGKHTDET VN