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RL26_CAEEL
ID   RL26_CAEEL              Reviewed;         142 AA.
AC   Q19869; Q8I121; Q9U3H7;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 138.
DE   RecName: Full=60S ribosomal protein L26;
GN   Name=rpl-26; ORFNames=F28C6.7;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=a;
CC         IsoId=Q19869-1; Sequence=Displayed;
CC       Name=b;
CC         IsoId=Q19869-2; Sequence=VSP_020728;
CC       Name=c;
CC         IsoId=Q19869-3; Sequence=VSP_020727;
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL24 family.
CC       {ECO:0000305}.
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DR   EMBL; Z68315; CAA92674.1; -; Genomic_DNA.
DR   EMBL; Z68315; CAA92678.1; -; Genomic_DNA.
DR   EMBL; Z68315; CAD59149.1; -; Genomic_DNA.
DR   PIR; T21486; T21486.
DR   PIR; T21490; T21490.
DR   RefSeq; NP_495823.1; NM_063422.4. [Q19869-1]
DR   RefSeq; NP_495824.1; NM_063423.6.
DR   RefSeq; NP_871965.1; NM_182165.5. [Q19869-3]
DR   AlphaFoldDB; Q19869; -.
DR   SMR; Q19869; -.
DR   BioGRID; 39707; 87.
DR   STRING; 6239.F28C6.7a.3; -.
DR   iPTMnet; Q19869; -.
DR   EPD; Q19869; -.
DR   PaxDb; Q19869; -.
DR   PeptideAtlas; Q19869; -.
DR   EnsemblMetazoa; F28C6.7a.1; F28C6.7a.1; WBGene00004440. [Q19869-1]
DR   EnsemblMetazoa; F28C6.7b.1; F28C6.7b.1; WBGene00004440. [Q19869-2]
DR   EnsemblMetazoa; F28C6.7b.2; F28C6.7b.2; WBGene00004440. [Q19869-2]
DR   EnsemblMetazoa; F28C6.7c.1; F28C6.7c.1; WBGene00004440. [Q19869-3]
DR   GeneID; 174379; -.
DR   KEGG; cel:CELE_F28C6.7; -.
DR   UCSC; F28C6.7a.1; c. elegans. [Q19869-1]
DR   CTD; 174379; -.
DR   WormBase; F28C6.7a; CE03278; WBGene00004440; rpl-26. [Q19869-1]
DR   WormBase; F28C6.7b; CE20731; WBGene00004440; rpl-26. [Q19869-2]
DR   WormBase; F28C6.7c; CE32883; WBGene00004440; rpl-26. [Q19869-3]
DR   eggNOG; KOG3401; Eukaryota.
DR   GeneTree; ENSGT00390000014165; -.
DR   HOGENOM; CLU_093240_0_0_1; -.
DR   InParanoid; Q19869; -.
DR   OMA; VRIMRGD; -.
DR   OrthoDB; 1488916at2759; -.
DR   PhylomeDB; Q19869; -.
DR   Reactome; R-CEL-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-CEL-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-CEL-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-CEL-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-CEL-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-CEL-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q19869; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00004440; Expressed in larva and 4 other tissues.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR   CDD; cd06089; KOW_RPL26; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   HAMAP; MF_01326_A; Ribosomal_L24_A; 1.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR041988; KOW_RPL26/RPL24.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR005825; Ribosomal_L24/26_CS.
DR   InterPro; IPR005756; Ribosomal_L26/L24P_euk/arc.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR11143; PTHR11143; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF16906; Ribosomal_L26; 1.
DR   SMART; SM00739; KOW; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   TIGRFAMs; TIGR01080; rplX_A_E; 1.
DR   PROSITE; PS01108; RIBOSOMAL_L24; 1.
PE   3: Inferred from homology;
KW   Alternative splicing; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein.
FT   CHAIN           1..142
FT                   /note="60S ribosomal protein L26"
FT                   /id="PRO_0000130795"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         104..142
FT                   /note="AITKLKLDKDRRALVERKAAGRSRVTGILKGKHTDETVN -> RFV (in
FT                   isoform b)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_020728"
FT   VAR_SEQ         104..142
FT                   /note="AITKLKLDKDRRALVERKAAGRSRVTGILKGKHTDETVN -> RSLSPS
FT                   (in isoform c)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_020727"
SQ   SEQUENCE   142 AA;  16075 MW;  B496362F0BFEC354 CRC64;
     MKVNPFVSSD SGKSRKAHFN APSHERRRIM SAPLTKELRT KHGIRAIPIR TDDEVVVMRG
     RHKGNTGRVL RCYRKKFVIH IDKITREKAN GSTVHIGIHP SKVAITKLKL DKDRRALVER
     KAAGRSRVTG ILKGKHTDET VN
 
 
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