ID   RL26_MACFA              Reviewed;         145 AA.
AC   P61256;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2004, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=60S ribosomal protein L26;
GN   Name=RPL26; ORFNames=QbsB-11436;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain stem;
RX   PubMed=11574149; DOI=10.1016/s0378-1119(01)00665-5;
RA   Osada N., Hida M., Kususda J., Tanuma R., Iseki K., Hirata M., Suto Y.,
RA   Hirai M., Terao K., Suzuki Y., Sugano S., Hashimoto K.;
RT   "Assignment of 118 novel cDNAs of cynomolgus monkey brain to human
RT   chromosomes.";
RL   Gene 275:31-37(2001).
RN   [2]
RP   ERRATUM OF PUBMED:11574149.
RA   Osada N., Hida M., Kusuda J., Tanuma R., Iseki K., Hirata M., Suto Y.,
RA   Hirai M., Terao K., Suzuki Y., Sugano S., Hashimoto K., Kususda J.;
RL   Gene 278:267-267(2001).
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:P61254}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit. Interacts with
CC       DHX33. {ECO:0000250|UniProtKB:P61254}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P61254}.
CC   -!- PTM: Ufmylated by UFL1 in response to endoplasmic reticulum stress,
CC       promoting reticulophagy of endoplasmic reticulum sheets.
CC       {ECO:0000250|UniProtKB:P61254}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL24 family.
CC       {ECO:0000305}.
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DR   EMBL; AB093679; BAC21653.1; -; mRNA.
DR   RefSeq; XP_005555698.1; XM_005555641.2.
DR   RefSeq; XP_005582914.1; XM_005582857.2.
DR   RefSeq; XP_015293116.1; XM_015437630.1.
DR   AlphaFoldDB; P61256; -.
DR   SMR; P61256; -.
DR   STRING; 9541.XP_005555698.1; -.
DR   Ensembl; ENSMFAT00000029569; ENSMFAP00000001392; ENSMFAG00000037250.
DR   GeneID; 102127561; -.
DR   GeneID; 102140788; -.
DR   KEGG; mcf:102127561; -.
DR   KEGG; mcf:102140788; -.
DR   CTD; 6154; -.
DR   VEuPathDB; HostDB:ENSMFAG00000029875; -.
DR   VEuPathDB; HostDB:ENSMFAG00000037250; -.
DR   eggNOG; KOG3401; Eukaryota.
DR   GeneTree; ENSGT00390000014165; -.
DR   OMA; VRIMRGD; -.
DR   OrthoDB; 1488916at2759; -.
DR   Proteomes; UP000233100; Chromosome 16.
DR   Bgee; ENSMFAG00000037250; Expressed in lymph node and 13 other tissues.
DR   GO; GO:0022626; C:cytosolic ribosome; IEA:Ensembl.
DR   GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR   GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0048027; F:mRNA 5'-UTR binding; IEA:Ensembl.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:Ensembl.
DR   GO; GO:0071480; P:cellular response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IEA:Ensembl.
DR   GO; GO:1902164; P:positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IEA:Ensembl.
DR   GO; GO:1902167; P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:Ensembl.
DR   GO; GO:1904803; P:regulation of translation involved in cellular response to UV; IEA:Ensembl.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:Ensembl.
DR   GO; GO:0006364; P:rRNA processing; IEA:Ensembl.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd06089; KOW_RPL26; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   HAMAP; MF_01326_A; Ribosomal_L24_A; 1.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR041988; KOW_RPL26/RPL24.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR005825; Ribosomal_L24/26_CS.
DR   InterPro; IPR005756; Ribosomal_L26/L24P_euk/arc.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR11143; PTHR11143; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF16906; Ribosomal_L26; 1.
DR   SMART; SM00739; KOW; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   TIGRFAMs; TIGR01080; rplX_A_E; 1.
DR   PROSITE; PS01108; RIBOSOMAL_L24; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Isopeptide bond; Phosphoprotein; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein; Ubl conjugation.
FT   CHAIN           1..145
FT                   /note="60S ribosomal protein L26"
FT                   /id="PRO_0000130788"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          122..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         139
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:P61254"
FT   CROSSLNK        136
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:P61254"
SQ   SEQUENCE   145 AA;  17258 MW;  049D53AB4E3F46B6 CRC64;
     MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR KDDEVQVVRG
     HYKGQQIGKV VQVYRKKYVI YIERVQREKA NGTTVHVGIH PSKVVITRLK LDKDRKKILE
     RKAKSRQVGK EKGKYKEETI EKMQE