RL27A_XENLA
ID RL27A_XENLA Reviewed; 148 AA.
AC P47830;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=60S ribosomal protein L27a;
DE AltName: Full=L22;
GN Name=rpl27a; Synonyms=rpl22;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=1579486; DOI=10.1093/nar/20.8.1859;
RA Loreni F., Francesconi A., Jappelli R., Amaldi F.;
RT "Analysis of mRNAs under translational control during Xenopus
RT embryogenesis: isolation of new ribosomal protein clones.";
RL Nucleic Acids Res. 20:1859-1863(1992).
CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC large ribonucleoprotein complex responsible for the synthesis of
CC proteins in the cell. {ECO:0000250|UniProtKB:P46776}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:P46776}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P46776}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL15 family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X64207; CAA45531.1; -; mRNA.
DR PIR; S22604; S22604.
DR RefSeq; NP_001081587.1; NM_001088118.1.
DR AlphaFoldDB; P47830; -.
DR SMR; P47830; -.
DR BioGRID; 99274; 1.
DR GeneID; 397938; -.
DR KEGG; xla:397938; -.
DR CTD; 397938; -.
DR Xenbase; XB-GENE-17332474; rpl27a.S.
DR OrthoDB; 1445443at2759; -.
DR Proteomes; UP000186698; Chromosome 7S.
DR Bgee; 397938; Expressed in lung and 19 other tissues.
DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 4.10.990.10; -; 1.
DR HAMAP; MF_01341; Ribosomal_L15; 1.
DR InterPro; IPR036227; L18e/L15P_sf.
DR InterPro; IPR027386; Rbsml_prot_L15/27a_N.
DR InterPro; IPR030878; Ribosomal_L15.
DR InterPro; IPR001196; Ribosomal_L15_CS.
DR InterPro; IPR021131; Ribosomal_L18e/L15P.
DR Pfam; PF00828; Ribosomal_L27A; 1.
DR SUPFAM; SSF52080; SSF52080; 1.
DR PROSITE; PS00475; RIBOSOMAL_L15; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..148
FT /note="60S ribosomal protein L27a"
FT /id="PRO_0000104885"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..35
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 148 AA; 16551 MW; 058469BE8B8F8422 CRC64;
MPSKLRKTRK LRGHVSHGHG RIGKHRKHPG GRGNAGGMHH HRINFDKYHP GYFGKVGMRH
YHLKKNQSFC PTINLDKLWT LVSEQTRLNH AKNLEGPAPI IDAVHAGYYK VLGKGKLPKQ
PVIVKAKFFS RKAEEKIKSV GGACVLGA