ID   RL27_BOVIN              Reviewed;         136 AA.
AC   P61356; Q3T0P1;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=60S ribosomal protein L27;
GN   Name=RPL27;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=12658628; DOI=10.1002/mrd.10292;
RA   Ishiwata H., Katsuma S., Kizaki K., Patel O.V., Nakano H., Takahashi T.,
RA   Imai K., Hirasawa A., Shiojima S., Ikawa H., Suzuki Y., Tsujimoto G.,
RA   Izaike Y., Todoroki J., Hashizume K.;
RT   "Characterization of gene expression profiles in early bovine pregnancy
RT   using a custom cDNA microarray.";
RL   Mol. Reprod. Dev. 65:9-18(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the large ribosomal subunit (By similarity).
CC       Required for proper rRNA processing and maturation of 28S and 5.8S
CC       rRNAs (By similarity). {ECO:0000250|UniProtKB:A1XQU5,
CC       ECO:0000250|UniProtKB:P61353}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit (By similarity).
CC       Interacts with RRP1B (By similarity). Component of the large ribosomal
CC       subunit. Interacts with RRP1B. Interacts with DHX33 (By similarity).
CC       {ECO:0000250|UniProtKB:A1XQU5, ECO:0000250|UniProtKB:P61353}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:P61353}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P61353}. Rough endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:A1XQU5}. Note=Detected on cytosolic polysomes
CC       (By similarity). Detected in ribosomes that are associated with the
CC       rough endoplasmic reticulum (By similarity).
CC       {ECO:0000250|UniProtKB:A1XQU5, ECO:0000250|UniProtKB:P61353}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL27 family.
CC       {ECO:0000305}.
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DR   EMBL; AB098983; BAC56473.1; -; mRNA.
DR   EMBL; BC102313; AAI02314.1; -; mRNA.
DR   RefSeq; NP_001029223.1; NM_001034051.2.
DR   AlphaFoldDB; P61356; -.
DR   SMR; P61356; -.
DR   STRING; 9913.ENSBTAP00000023183; -.
DR   PaxDb; P61356; -.
DR   PeptideAtlas; P61356; -.
DR   PRIDE; P61356; -.
DR   Ensembl; ENSBTAT00000023183; ENSBTAP00000023183; ENSBTAG00000017441.
DR   GeneID; 404137; -.
DR   KEGG; bta:404137; -.
DR   CTD; 6155; -.
DR   VEuPathDB; HostDB:ENSBTAG00000017441; -.
DR   VGNC; VGNC:55868; RPL27.
DR   eggNOG; KOG3418; Eukaryota.
DR   GeneTree; ENSGT00390000010721; -.
DR   HOGENOM; CLU_067359_0_1_1; -.
DR   InParanoid; P61356; -.
DR   OMA; HPFPYAI; -.
DR   OrthoDB; 1584965at2759; -.
DR   TreeFam; TF314648; -.
DR   Reactome; R-BTA-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-BTA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-BTA-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-BTA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-BTA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   Proteomes; UP000009136; Chromosome 19.
DR   Bgee; ENSBTAG00000017441; Expressed in diaphragm and 106 other tissues.
DR   GO; GO:0098556; C:cytoplasmic side of rough endoplasmic reticulum membrane; ISS:UniProtKB.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0015934; C:large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd06090; KOW_RPL27; 1.
DR   Gene3D; 2.30.30.770; -; 1.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR041991; KOW_RPL27.
DR   InterPro; IPR038655; L27e_sf.
DR   InterPro; IPR001141; Ribosomal_L27e.
DR   InterPro; IPR018262; Ribosomal_L27e_CS.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR10497; PTHR10497; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF01777; Ribosomal_L27e; 1.
DR   SMART; SM00739; KOW; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   PROSITE; PS01107; RIBOSOMAL_L27E; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Cytoplasm; Endoplasmic reticulum; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..136
FT                   /note="60S ribosomal protein L27"
FT                   /id="PRO_0000126074"
FT   DOMAIN          5..40
FT                   /note="KOW"
FT   MOD_RES         27
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P61353"
FT   MOD_RES         93
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P61353"
SQ   SEQUENCE   136 AA;  15798 MW;  73F4151495029A32 CRC64;
     MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP RKVTAAMGKK
     KIAKRSKIKS FVKVYNYNHL MPTRYSVDIP LDKTVVNKDV FRDPALKRKA RREAKVKFEE
     RYKTGKNKWF FQKLRF