ID   RL27_CANLF              Reviewed;         136 AA.
AC   Q9XSU7;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=60S ribosomal protein L27;
GN   Name=RPL27; ORFNames=B173;
OS   Canis lupus familiaris (Dog) (Canis familiaris).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis.
OX   NCBI_TaxID=9615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Thyroid;
RX   PubMed=10964405; DOI=10.1006/abio.2000.4674;
RA   Pichon B., Mercan D., Pouillon V., Christophe-Hobertus C., Christophe D.;
RT   "A method for the large-scale cloning of nuclear proteins and nuclear
RT   targeting sequences on a functional basis.";
RL   Anal. Biochem. 284:231-239(2000).
CC   -!- FUNCTION: Component of the large ribosomal subunit (By similarity).
CC       Required for proper rRNA processing and maturation of 28S and 5.8S
CC       rRNAs (By similarity). {ECO:0000250|UniProtKB:A1XQU5,
CC       ECO:0000250|UniProtKB:P61353}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit (By similarity).
CC       Interacts with RRP1B (By similarity). Component of the large ribosomal
CC       subunit. Interacts with RRP1B. Interacts with DHX33 (By similarity).
CC       {ECO:0000250|UniProtKB:A1XQU5, ECO:0000250|UniProtKB:P61353}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:P61353}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P61353}. Rough endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:A1XQU5}. Note=Detected on cytosolic polysomes
CC       (By similarity). Detected in ribosomes that are associated with the
CC       rough endoplasmic reticulum (By similarity).
CC       {ECO:0000250|UniProtKB:A1XQU5, ECO:0000250|UniProtKB:P61353}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL27 family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAB46818.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AJ388516; CAB46818.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001003102.2; NM_001003102.2.
DR   AlphaFoldDB; Q9XSU7; -.
DR   SMR; Q9XSU7; -.
DR   STRING; 9615.ENSCAFP00000021561; -.
DR   PaxDb; Q9XSU7; -.
DR   PRIDE; Q9XSU7; -.
DR   GeneID; 403688; -.
DR   KEGG; cfa:403688; -.
DR   CTD; 6155; -.
DR   eggNOG; KOG3418; Eukaryota.
DR   InParanoid; Q9XSU7; -.
DR   OrthoDB; 1584965at2759; -.
DR   Proteomes; UP000002254; Unplaced.
DR   GO; GO:0098556; C:cytoplasmic side of rough endoplasmic reticulum membrane; ISS:UniProtKB.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0015934; C:large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd06090; KOW_RPL27; 1.
DR   Gene3D; 2.30.30.770; -; 1.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR041991; KOW_RPL27.
DR   InterPro; IPR038655; L27e_sf.
DR   InterPro; IPR001141; Ribosomal_L27e.
DR   InterPro; IPR018262; Ribosomal_L27e_CS.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR10497; PTHR10497; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF01777; Ribosomal_L27e; 1.
DR   SMART; SM00739; KOW; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   PROSITE; PS01107; RIBOSOMAL_L27E; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Cytoplasm; Endoplasmic reticulum; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..136
FT                   /note="60S ribosomal protein L27"
FT                   /id="PRO_0000126075"
FT   DOMAIN          5..40
FT                   /note="KOW"
FT   MOD_RES         27
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P61353"
FT   MOD_RES         93
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P61353"
SQ   SEQUENCE   136 AA;  15770 MW;  5404151495029A2D CRC64;
     MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP RKVTAAMGKK
     KIAKRSKIKS FVKVYNYNHL MPTRYSVDIP LDKTVVNKDV FRDPALKRKA RREAKVKFEE
     KYKTGKNKWF FQKLRF