RL281_ARATH
ID RL281_ARATH Reviewed; 143 AA.
AC O82204;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=60S ribosomal protein L28-1 {ECO:0000303|PubMed:11598216};
DE AltName: Full=Protein ASYMMETRIC LEAVES1/2 ENHANCER 5 {ECO:0000303|PubMed:18305007};
GN Name=RPL28A {ECO:0000303|PubMed:11598216};
GN Synonyms=AE5 {ECO:0000303|PubMed:18305007};
GN OrderedLocusNames=At2g19730 {ECO:0000312|Araport:AT2G19730};
GN ORFNames=F6F22.24 {ECO:0000312|EMBL:AAC62149.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=11598216; DOI=10.1104/pp.010265;
RA Barakat A., Szick-Miranda K., Chang I.-F., Guyot R., Blanc G., Cooke R.,
RA Delseny M., Bailey-Serres J.;
RT "The organization of cytoplasmic ribosomal protein genes in the Arabidopsis
RT genome.";
RL Plant Physiol. 127:398-415(2001).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=cv. Landsberg erecta;
RX PubMed=17272265; DOI=10.1074/mcp.m600408-mcp200;
RA Maor R., Jones A., Nuehse T.S., Studholme D.J., Peck S.C., Shirasu K.;
RT "Multidimensional protein identification technology (MudPIT) analysis of
RT ubiquitinated proteins in plants.";
RL Mol. Cell. Proteomics 6:601-610(2007).
RN [6]
RP FUNCTION, DISRUPTION PHENOTYPE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE,
RP AND SUBCELLULAR LOCATION.
RC STRAIN=cv. Columbia, and cv. Landsberg erecta;
RX PubMed=18305007; DOI=10.1242/dev.017913;
RA Yao Y., Ling Q., Wang H., Huang H.;
RT "Ribosomal proteins promote leaf adaxial identity.";
RL Development 135:1325-1334(2008).
CC -!- FUNCTION: Component of the large ribosomal subunit (By similarity).
CC Essential in leaf polarity establishment, probably having a role for
CC translation in leaf dorsoventral patterning to specify leaf adaxial
CC identity (PubMed:18305007). {ECO:0000250|UniProtKB:P46779,
CC ECO:0000269|PubMed:18305007}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:P46779}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:18305007}. Nucleus
CC {ECO:0000269|PubMed:18305007}. Nucleus, nucleolus
CC {ECO:0000269|PubMed:18305007}. Nucleus, nucleoplasm
CC {ECO:0000269|PubMed:18305007}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, stems, leaves,
CC inflorescences and siliques. {ECO:0000269|PubMed:18305007}.
CC -!- DEVELOPMENTAL STAGE: Detected in the embryo and leaf primordia at
CC earlier developmental stages (PubMed:18305007). In reproductive organs,
CC expressed in the inflorescence meristem, floral primordia and four
CC types of young floral organs (PubMed:18305007).
CC {ECO:0000269|PubMed:18305007}.
CC -!- DISRUPTION PHENOTYPE: Pale green leaves and slightly longer early
CC appearing leaves (PubMed:18305007). Delayed leaf growth and abnormal
CC leaf patterning, with the abaxial mesophyll features appearing in the
CC adaxial mesophyll domain (PubMed:18305007). More proximal vein
CC branching in the petiole and reduced number of small veins at later
CC leaf developmental stages (PubMed:18305007). Abnormal inflorescences
CC terminating early and producing several secondary inflorescences
CC (PubMed:18305007). Double mutant ae5-1 as2-101 exhibits an increased
CC number of lotus- and needle-like leaves (PubMed:18305007). The double
CC mutant ae5 as1/2 produces severe abaxialized leaves (PubMed:18305007).
CC {ECO:0000269|PubMed:18305007}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL28 family.
CC {ECO:0000305}.
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DR EMBL; AC005169; AAC62149.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06918.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06919.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06920.1; -; Genomic_DNA.
DR EMBL; AY050769; AAK92704.1; -; mRNA.
DR EMBL; AY079378; AAL85109.1; -; mRNA.
DR PIR; D84580; D84580.
DR RefSeq; NP_001031374.1; NM_001036297.2.
DR RefSeq; NP_001077920.1; NM_001084451.1.
DR RefSeq; NP_179563.1; NM_127531.4.
DR AlphaFoldDB; O82204; -.
DR SMR; O82204; -.
DR BioGRID; 1847; 8.
DR IntAct; O82204; 3.
DR STRING; 3702.AT2G19730.3; -.
DR MetOSite; O82204; -.
DR PaxDb; O82204; -.
DR PRIDE; O82204; -.
DR ProteomicsDB; 225930; -.
DR EnsemblPlants; AT2G19730.1; AT2G19730.1; AT2G19730.
DR EnsemblPlants; AT2G19730.2; AT2G19730.2; AT2G19730.
DR EnsemblPlants; AT2G19730.3; AT2G19730.3; AT2G19730.
DR GeneID; 816492; -.
DR Gramene; AT2G19730.1; AT2G19730.1; AT2G19730.
DR Gramene; AT2G19730.2; AT2G19730.2; AT2G19730.
DR Gramene; AT2G19730.3; AT2G19730.3; AT2G19730.
DR KEGG; ath:AT2G19730; -.
DR Araport; AT2G19730; -.
DR TAIR; locus:2052010; AT2G19730.
DR eggNOG; KOG3412; Eukaryota.
DR HOGENOM; CLU_106801_2_0_1; -.
DR InParanoid; O82204; -.
DR OMA; SHDLAWE; -.
DR OrthoDB; 1593474at2759; -.
DR PhylomeDB; O82204; -.
DR PRO; PR:O82204; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O82204; baseline and differential.
DR Genevisible; O82204; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; HDA:TAIR.
DR GO; GO:0022626; C:cytosolic ribosome; HDA:TAIR.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR GO; GO:0005730; C:nucleolus; IDA:UniProtKB.
DR GO; GO:0005654; C:nucleoplasm; IDA:UniProtKB.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0009505; C:plant-type cell wall; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0003735; F:structural constituent of ribosome; IDA:CAFA.
DR GO; GO:0009955; P:adaxial/abaxial pattern specification; IMP:UniProtKB.
DR GO; GO:0009965; P:leaf morphogenesis; IMP:UniProtKB.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR InterPro; IPR029004; L28e/Mak16.
DR InterPro; IPR002672; Ribosomal_L28e.
DR PANTHER; PTHR10544; PTHR10544; 1.
DR Pfam; PF01778; Ribosomal_L28e; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Nucleus; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein.
FT CHAIN 1..143
FT /note="60S ribosomal protein L28-1"
FT /id="PRO_0000244743"
SQ SEQUENCE 143 AA; 15895 MW; BD1FBFFED28E5550 CRC64;
MATVPGQLIW EIVKNNNCFL VKQFGRGNSK VQFSKETNNL TNVHSYKHSG LANKKTVTIQ
AADKDQAVVL ATTKTKKQNK PKLSVNKSIL KKEFPRMSKA VANQVVDNYY RPDLKKAALA
RLSAISKGLR VAKSGAKQRN RQA
