ID   ATPF1_MOUSE             Reviewed;         324 AA.
AC   Q811I0;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=ATP synthase mitochondrial F1 complex assembly factor 1;
DE   Flags: Precursor;
GN   Name=Atpaf1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=FVB/N; TISSUE=Mammary tumor;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   TISSUE SPECIFICITY.
RX   PubMed=12965202; DOI=10.1016/s0014-5793(03)00890-1;
RA   Pickova A., Paul J., Petruzzella V., Houstek J.;
RT   "Differential expression of ATPAF1 and ATPAF2 genes encoding F(1)-ATPase
RT   assembly proteins in mouse tissues.";
RL   FEBS Lett. 551:42-46(2003).
RN   [4]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Lung, and Spleen;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- FUNCTION: May play an essential role for the assembly of the
CC       mitochondrial F1-F0 complex. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with ATP5F1B. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Widely expressed but with low level.
CC       {ECO:0000269|PubMed:12965202}.
CC   -!- SIMILARITY: Belongs to the ATP11 family. {ECO:0000305}.
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DR   EMBL; AL626806; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC044874; AAH44874.1; -; mRNA.
DR   CCDS; CCDS89811.1; -.
DR   AlphaFoldDB; Q811I0; -.
DR   SMR; Q811I0; -.
DR   STRING; 10090.ENSMUSP00000135831; -.
DR   iPTMnet; Q811I0; -.
DR   PhosphoSitePlus; Q811I0; -.
DR   SwissPalm; Q811I0; -.
DR   EPD; Q811I0; -.
DR   MaxQB; Q811I0; -.
DR   PaxDb; Q811I0; -.
DR   PRIDE; Q811I0; -.
DR   ProteomicsDB; 277218; -.
DR   Antibodypedia; 32819; 93 antibodies from 19 providers.
DR   Ensembl; ENSMUST00000239030; ENSMUSP00000158943; ENSMUSG00000028710.
DR   MGI; MGI:2180560; Atpaf1.
DR   VEuPathDB; HostDB:ENSMUSG00000028710; -.
DR   eggNOG; KOG3281; Eukaryota.
DR   GeneTree; ENSGT00390000012765; -.
DR   InParanoid; Q811I0; -.
DR   PhylomeDB; Q811I0; -.
DR   ChiTaRS; Atpaf1; mouse.
DR   PRO; PR:Q811I0; -.
DR   Proteomes; UP000000589; Chromosome 4.
DR   RNAct; Q811I0; protein.
DR   Bgee; ENSMUSG00000028710; Expressed in facial nucleus and 221 other tissues.
DR   ExpressionAtlas; Q811I0; baseline and differential.
DR   GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR   GO; GO:0033615; P:mitochondrial proton-transporting ATP synthase complex assembly; IBA:GO_Central.
DR   InterPro; IPR010591; ATP11.
DR   PANTHER; PTHR13126; PTHR13126; 1.
DR   Pfam; PF06644; ATP11; 1.
PE   1: Evidence at protein level;
KW   Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..54
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           55..324
FT                   /note="ATP synthase mitochondrial F1 complex assembly
FT                   factor 1"
FT                   /id="PRO_0000318916"
SQ   SEQUENCE   324 AA;  36355 MW;  F7AF976B85FE0358 CRC64;
     MAAVVSAAGG ACPAVLQVAG LYRGLCAVRS RALGLGFVSP AQLRVFPVRR GSGLPPEGAD
     GSGVSELEAN PFYDRYRDKI QQLRRSDPAA FESRLEKRSE FRKQPVGHSK QSDFIKCMEQ
     KTDALGKQPV SKGFTKDKTL SSVFNVEMVK DKTAEEIKQI WQQYFSAKDT VYAVIPKEKF
     DLIWNRAQSC PTFLCALPRR DGYEFFVGQW TGTELHFTAL INIQTRGDAA ASQLILYHYP
     ELKEEKGIVL MTAEMDSTFL NVVEAQCIAN QVQLFYATDR KEIYGLVETF NFRPNEFKYM
     SVIAELEQSG LGAELKRAQN QDKT