ID   RL29_RAT                Reviewed;         156 AA.
AC   P25886;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=60S ribosomal protein L29;
DE   AltName: Full=P23;
GN   Name=Rpl29;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Wistar; TISSUE=Pancreas;
RX   PubMed=1735422; DOI=10.1111/j.1432-1033.1992.tb16555.x;
RA   Svoboda M., Ciccarelli E., Vandermeers-Piret M.C., Nagy A.M.,
RA   van de Weerdt C., Bollen A., Vandermeers A., Christophe J.;
RT   "Purification, primary structure and molecular cloning of a rat ribosomal
RT   protein showing homology with yeast ribosomal protein YL34.";
RL   Eur. J. Biochem. 203:341-346(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PROTEIN SEQUENCE OF 2-35.
RC   STRAIN=Sprague-Dawley; TISSUE=Liver;
RX   PubMed=8484767; DOI=10.1006/bbrc.1993.1455;
RA   Chan Y.-L., Olvera J., Paz V., Wool I.G.;
RT   "The primary structure of rat ribosomal protein L29.";
RL   Biochem. Biophys. Res. Commun. 192:583-589(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [4]
RP   PROTEIN SEQUENCE OF 2-29.
RC   TISSUE=Liver;
RX   PubMed=1544448; DOI=10.1016/0014-5793(92)80061-k;
RA   Oestvold A.C., Hullstein I., Sletten K.;
RT   "p23, a novel mammalian nucleic acid-binding protein with homology to the
RT   yeast ribosomal protein YL43.";
RL   FEBS Lett. 298:219-222(1992).
RN   [5]
RP   METHYLATION AT LYS-5.
RX   PubMed=9219540; DOI=10.1111/j.1432-1033.1997.00786.x;
RA   Williamson N.A., Raliegh J., Morrice N.A., Wettenhall R.E.;
RT   "Post-translational processing of rat ribosomal proteins. Ubiquitous
RT   methylation of Lys22 within the zinc-finger motif of RL40 (carboxy-terminal
RT   extension protein 52) and tissue-specific methylation of Lys4 in RL29.";
RL   Eur. J. Biochem. 246:786-793(1997).
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:P47914}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P47914}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P47914}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL29 family.
CC       {ECO:0000305}.
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DR   EMBL; X68283; CAA48344.1; -; mRNA.
DR   EMBL; X60744; CAA43146.1; -; mRNA.
DR   EMBL; BC086404; AAH86404.1; -; mRNA.
DR   PIR; S20594; R6RT43.
DR   RefSeq; NP_058846.1; NM_017150.1.
DR   AlphaFoldDB; P25886; -.
DR   SMR; P25886; -.
DR   STRING; 10116.ENSRNOP00000014849; -.
DR   iPTMnet; P25886; -.
DR   PhosphoSitePlus; P25886; -.
DR   jPOST; P25886; -.
DR   PaxDb; P25886; -.
DR   PRIDE; P25886; -.
DR   GeneID; 29283; -.
DR   KEGG; rno:29283; -.
DR   UCSC; RGD:62069; rat.
DR   CTD; 6159; -.
DR   RGD; 62069; Rpl29.
DR   VEuPathDB; HostDB:ENSRNOG00000011138; -.
DR   eggNOG; KOG3504; Eukaryota.
DR   HOGENOM; CLU_139508_0_0_1; -.
DR   InParanoid; P25886; -.
DR   OMA; TYIAHPK; -.
DR   OrthoDB; 1608986at2759; -.
DR   PhylomeDB; P25886; -.
DR   TreeFam; TF313858; -.
DR   Reactome; R-RNO-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-RNO-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-RNO-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-RNO-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-RNO-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-RNO-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-RNO-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:P25886; -.
DR   Proteomes; UP000002494; Chromosome 8.
DR   Bgee; ENSRNOG00000011138; Expressed in ovary and 19 other tissues.
DR   Genevisible; P25886; RN.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IDA:RGD.
DR   GO; GO:0022626; C:cytosolic ribosome; ISO:RGD.
DR   GO; GO:0019898; C:extrinsic component of membrane; ISO:RGD.
DR   GO; GO:0042788; C:polysomal ribosome; ISO:RGD.
DR   GO; GO:0005840; C:ribosome; IDA:RGD.
DR   GO; GO:0045202; C:synapse; ISO:RGD.
DR   GO; GO:0008201; F:heparin binding; ISO:RGD.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISO:RGD.
DR   GO; GO:0007568; P:aging; IEP:RGD.
DR   GO; GO:0008283; P:cell population proliferation; ISO:RGD.
DR   GO; GO:0031589; P:cell-substrate adhesion; ISO:RGD.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR   GO; GO:0035264; P:multicellular organism growth; ISO:RGD.
DR   GO; GO:0006412; P:translation; ISO:RGD.
DR   InterPro; IPR002673; Ribosomal_L29e.
DR   PANTHER; PTHR12884; PTHR12884; 1.
DR   Pfam; PF01779; Ribosomal_L29e; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Cytoplasm; Direct protein sequencing; Methylation;
KW   Phosphoprotein; Reference proteome; Repeat; Ribonucleoprotein;
KW   Ribosomal protein.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:1544448,
FT                   ECO:0000269|PubMed:8484767"
FT   CHAIN           2..156
FT                   /note="60S ribosomal protein L29"
FT                   /id="PRO_0000219138"
FT   REPEAT          129..136
FT                   /note="1"
FT   REPEAT          137..144
FT                   /note="2"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          116..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          129..144
FT                   /note="2 X 8 AA tandem repeats of A-X-A-K-A-P-A-[KQ]"
FT   COMPBIAS        1..22
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         5
FT                   /note="N6-methyllysine"
FT                   /evidence="ECO:0000269|PubMed:9219540"
FT   MOD_RES         31
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P47914"
FT   MOD_RES         33
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P47914"
SQ   SEQUENCE   156 AA;  17326 MW;  E94AAE76497CDF03 CRC64;
     MAKSKNHTTH NQSRKWHRNG IKKPRSQRYE SLKGVDPKFL RNMRFAKKHN KKGLKKMQAN
     NAKAVSARAE AIKALVKPQA VKPKMPKGSS RKLSRLAFIA HPKLGKKIRS YMAKGRRLCQ
     PKPKVQTKAE AKAPAKAQAK APAQAPKGAQ APVKAP