ID   RL2A_SCHPO              Reviewed;         253 AA.
AC   P0CT70; P08093; P14067; P36593; Q9UU31;
DT   24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT   24-JUN-2015, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=60S ribosomal protein L2-A;
DE   AltName: Full=K37;
DE   AltName: Full=K5;
DE   AltName: Full=KD4;
GN   Name=rpl801; Synonyms=rpk5, rpk5a, rpl2a, rpl8-1;
GN   ORFNames=SPAC1F7.13c, SPAC21E11.02;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2611912; DOI=10.1007/bf00340715;
RA   Gatermann K.B., Teletski C., Gross T., Kaeufer N.F.;
RT   "A ribosomal protein gene family from Schizosaccharomyces pombe consisting
RT   of three active members.";
RL   Curr. Genet. 16:361-367(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- MISCELLANEOUS: There are three genes for L2 in S.pombe.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL2 family.
CC       {ECO:0000305}.
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DR   EMBL; X51659; CAA35971.1; -; Genomic_DNA.
DR   EMBL; CU329670; CAA91960.1; -; Genomic_DNA.
DR   PIR; S07377; S07377.
DR   PIR; T40711; R5ZPD4.
DR   RefSeq; NP_595244.1; NM_001021150.2.
DR   RefSeq; NP_595709.1; NM_001021606.2.
DR   RefSeq; XP_001713102.1; XM_001713050.2.
DR   AlphaFoldDB; P0CT70; -.
DR   SMR; P0CT70; -.
DR   STRING; 4896.SPAC1F7.13c.1; -.
DR   iPTMnet; P0CT70; -.
DR   PaxDb; P0CT70; -.
DR   EnsemblFungi; SPAC1F7.13c.1; SPAC1F7.13c.1:pep; SPAC1F7.13c.
DR   EnsemblFungi; SPBC2F12.07c.1; SPBC2F12.07c.1:pep; SPBC2F12.07c.
DR   EnsemblFungi; SPBC839.04.1; SPBC839.04.1:pep; SPBC839.04.
DR   GeneID; 2540366; -.
DR   GeneID; 2541191; -.
DR   KEGG; spo:SPBC2F12.07c; -.
DR   KEGG; spo:SPBC839.04; -.
DR   PomBase; SPAC1F7.13c; rpl801.
DR   VEuPathDB; FungiDB:SPAC1F7.13c; -.
DR   VEuPathDB; FungiDB:SPBC2F12.07c; -.
DR   VEuPathDB; FungiDB:SPBC839.04; -.
DR   eggNOG; KOG2309; Eukaryota.
DR   OMA; HPYKFKM; -.
DR   PhylomeDB; P0CT70; -.
DR   Reactome; R-SPO-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-SPO-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-SPO-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-SPO-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-SPO-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-SPO-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:P0CT70; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   ExpressionAtlas; P0CT70; differential.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; ISO:PomBase.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; ISM:PomBase.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISO:PomBase.
DR   GO; GO:0002181; P:cytoplasmic translation; ISO:PomBase.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   Gene3D; 4.10.950.10; -; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR022666; Rbsml_prot_L2_RNA-bd_dom.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR002171; Ribosomal_L2.
DR   InterPro; IPR022669; Ribosomal_L2_C.
DR   InterPro; IPR022671; Ribosomal_L2_CS.
DR   InterPro; IPR014726; Ribosomal_L2_dom3.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR13691; PTHR13691; 1.
DR   Pfam; PF00181; Ribosomal_L2; 1.
DR   Pfam; PF03947; Ribosomal_L2_C; 1.
DR   PIRSF; PIRSF002158; Ribosomal_L2; 1.
DR   SMART; SM01383; Ribosomal_L2; 1.
DR   SMART; SM01382; Ribosomal_L2_C; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   PROSITE; PS00467; RIBOSOMAL_L2; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   CHAIN           1..253
FT                   /note="60S ribosomal protein L2-A"
FT                   /id="PRO_0000129760"
FT   CONFLICT        135
FT                   /note="I -> S (in Ref. 1; CAA35971)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   253 AA;  27100 MW;  5FFB503E4376EA63 CRC64;
     MGRVIRAQRK SGGIFQAHTR LRKGAAQLRT LDFAERHGYI RGVVQKIIHD PGRGAPLAKV
     AFRNPYHYRT DVETFVATEG MYTGQFVYCG KNAALTVGNV LPVGEMPEGT IISNVEEKAG
     DRGALGRSSG NYVIIVGHDV DTGKTRVKLP SGAKKVVPSS ARGVVGIVAG GGRIDKPLLK
     AGRAFHKYRV KRNCWPRTRG VAMNPVDHPH GGGNHQHVGH STTVPRQSAP GQKVGLIAAR
     RTGLLRGAAA VEN