ID   AATC_RHIME              Reviewed;         405 AA.
AC   O87320;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Putative aminotransferase AatC;
DE            EC=2.6.1.-;
GN   Name=aatC; OrderedLocusNames=R01723; ORFNames=SMc00294;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481430; DOI=10.1073/pnas.161294398;
RA   Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA   Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA   Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA   Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA   Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT   "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT   meliloti strain 1021.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-234.
RC   STRAIN=1021;
RX   PubMed=9734305; DOI=10.1139/w98-033;
RA   Willis L.B., Walker G.C.;
RT   "The phbC (poly-beta-hydroxybutyrate synthase) gene of Rhizobium
RT   (Sinorhizobium) meliloti and characterization of phbC mutants.";
RL   Can. J. Microbiol. 44:554-564(1998).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000305};
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC61900.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AL591688; CAC46302.1; -; Genomic_DNA.
DR   EMBL; AF031938; AAC61900.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_385829.1; NC_003047.1.
DR   RefSeq; WP_010969423.1; NC_003047.1.
DR   AlphaFoldDB; O87320; -.
DR   SMR; O87320; -.
DR   STRING; 266834.SMc00294; -.
DR   EnsemblBacteria; CAC46302; CAC46302; SMc00294.
DR   GeneID; 61603196; -.
DR   KEGG; sme:SMc00294; -.
DR   PATRIC; fig|266834.11.peg.3160; -.
DR   eggNOG; COG0436; Bacteria.
DR   HOGENOM; CLU_017584_4_5_5; -.
DR   OMA; YPHMPTG; -.
DR   Proteomes; UP000001976; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR   GO; GO:1901605; P:alpha-amino acid metabolic process; IEA:UniProt.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR004838; NHTrfase_class1_PyrdxlP-BS.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   PROSITE; PS00105; AA_TRANSFER_CLASS_1; 1.
PE   3: Inferred from homology;
KW   Aminotransferase; Cytoplasm; Pyridoxal phosphate; Reference proteome;
KW   Transferase.
FT   CHAIN           1..405
FT                   /note="Putative aminotransferase AatC"
FT                   /id="PRO_0000123923"
FT   MOD_RES         238
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        43
FT                   /note="P -> R (in Ref. 3; AAC61900)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   405 AA;  44576 MW;  D4A1E708A5F2D473 CRC64;
     MEEFHKVRRL PPYVFEQVNR LKASARAAGA DIIDLGMGNP DLPTPQSIVD KLCEVVQDPR
     THRYSSSKGI PGLRRAQAAY YARRFGVKLN PETQVVATLG SKEGFANMAQ AITAPGDVVL
     CPNPTYPIHA FGFLMAGGVI RSISVEPDES FFPPLERAVR HSIPKPLALI LNYPSNPTAQ
     VATLDFYKDV IAFAKKHDII VLSDLAYSEI YFDDAPPPSV LEVPGATDVT VEFTSMSKTF
     SMPGWRMGFA VGNERLIAAL TRVKSYLDYG AFTPIQVAAT QALNGDGSDI AEVRAIYKRR
     RDVMVESFGK AGFEVPPPPA TMFAWAKIPE KFRHLGSLEF SKLLVEKADV AVAPGIGFGE
     QGDDYVRLAL VENEHRIRQA ARNIKRFLSS ADETMHNVIS LNAHR