ID   AATF_CHICK              Reviewed;         574 AA.
AC   Q5ZIM6;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Protein AATF;
DE   AltName: Full=Apoptosis-antagonizing transcription factor;
GN   Name=AATF; ORFNames=RCJMB04_24o4;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: May function as a general inhibitor of the histone
CC       deacetylase HDAC1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AATF family. {ECO:0000305}.
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DR   EMBL; AJ720758; CAG32417.1; -; mRNA.
DR   RefSeq; NP_001025895.1; NM_001030724.2.
DR   AlphaFoldDB; Q5ZIM6; -.
DR   SMR; Q5ZIM6; -.
DR   STRING; 9031.ENSGALP00000008693; -.
DR   PaxDb; Q5ZIM6; -.
DR   Ensembl; ENSGALT00000008707; ENSGALP00000008693; ENSGALG00000005420.
DR   GeneID; 417653; -.
DR   KEGG; gga:417653; -.
DR   CTD; 26574; -.
DR   VEuPathDB; HostDB:geneid_417653; -.
DR   eggNOG; KOG2773; Eukaryota.
DR   GeneTree; ENSGT00390000000288; -.
DR   InParanoid; Q5ZIM6; -.
DR   OMA; LINFMAP; -.
DR   OrthoDB; 794860at2759; -.
DR   PhylomeDB; Q5ZIM6; -.
DR   PRO; PR:Q5ZIM6; -.
DR   Proteomes; UP000000539; Chromosome 19.
DR   Bgee; ENSGALG00000005420; Expressed in ovary and 12 other tissues.
DR   ExpressionAtlas; Q5ZIM6; baseline and differential.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR025160; AATF.
DR   InterPro; IPR039223; AATF/Bfr2.
DR   InterPro; IPR012617; AATF_C.
DR   PANTHER; PTHR15565; PTHR15565; 1.
DR   Pfam; PF13339; AATF-Che1; 1.
DR   Pfam; PF08164; TRAUB; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..574
FT                   /note="Protein AATF"
FT                   /id="PRO_0000056619"
FT   REGION          82..205
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          302..340
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          553..574
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        86..104
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        105..126
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..183
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        184..202
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        305..340
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        559..574
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   574 AA;  65047 MW;  92E054D65EA87F58 CRC64;
     MAAPLAQQLE ELLNPRPDLR DPEDDAEEAT VAKVIDRFED ETADDVLPVG NIRKKASVSL
     LEADQRYSGK ATSRKALQEE LWGDALSEEG SAEEALDEWY SGSEDSEDNG SSGSKTEEQP
     SSAGSDQEDN LEDDEERDSS AKAPKFSFQN ITDFEKFAEG MDDVGSSDGE DEDDASMEEG
     SDDEKYEGEN HDHVKDTNDN EDDGGVMTFS KGQTSDEVEK GKAVKNQLAL WDQILEGRIK
     MQKALVIVNR LPQPDTFPLF RKEGGQEFDS AVESCCKAVD TLLRVLVDIQ DELLYQCPGT
     RHLVDGKQSK PESDDEIPSS SDEERAGEAQ EKRKRPPKRK LKAEDIPEFI AKRYSDYRTY
     RNHILQKWHE KTKLASGKMA KGFGAFERSI LTQIDHILMD KERLLRRTQT KRSVYRVLGK
     EEQDSHPVPE HLPENSEVLP QADSNRHLKD IDEEIFDDDD FYHQLLRELI ERKTTSLDPN
     DQVAMGRQWL AIQKLRSKIK KKVDRKASKG RKIRYHVHSK LVSFMAPIDH CTMNDDARTE
     LYRSLFGRMM QSEGPERGWH PGPPAPAGSA PYTL