RL2_SYNP6
ID RL2_SYNP6 Reviewed; 287 AA.
AC O24692; Q5N0W2;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 2.
DT 25-MAY-2022, entry version 119.
DE RecName: Full=50S ribosomal protein L2 {ECO:0000255|HAMAP-Rule:MF_01320};
GN Name=rplB {ECO:0000255|HAMAP-Rule:MF_01320};
GN Synonyms=rpl2 {ECO:0000255|HAMAP-Rule:MF_01320};
GN OrderedLocusNames=syc1868_d;
OS Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis
OS nidulans).
OC Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX NCBI_TaxID=269084;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9300823; DOI=10.1016/s0378-1119(97)00169-8;
RA Sugita M., Sugishita H., Fujishiro T., Tsuboi M., Sugita C., Endo T.,
RA Sugiura M.;
RT "Organization of a large gene cluster encoding ribosomal proteins in the
RT cyanobacterium Synechococcus sp. strain PCC 6301: comparison of gene
RT clusters among cyanobacteria, eubacteria and chloroplast genomes.";
RL Gene 195:73-79(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27144 / PCC 6301 / SAUG 1402/1;
RX PubMed=17211581; DOI=10.1007/s11120-006-9122-4;
RA Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M.,
RA Kanehisa M., Omata T., Sugiura M., Sugita M.;
RT "Complete nucleotide sequence of the freshwater unicellular cyanobacterium
RT Synechococcus elongatus PCC 6301 chromosome: gene content and
RT organization.";
RL Photosyn. Res. 93:55-67(2007).
CC -!- FUNCTION: One of the primary rRNA binding proteins. Required for
CC association of the 30S and 50S subunits to form the 70S ribosome, for
CC tRNA binding and peptide bond formation. It has been suggested to have
CC peptidyltransferase activity; this is somewhat controversial. Makes
CC several contacts with the 16S rRNA in the 70S ribosome.
CC {ECO:0000255|HAMAP-Rule:MF_01320}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a bridge to the 30S
CC subunit in the 70S ribosome. {ECO:0000255|HAMAP-Rule:MF_01320}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL2 family.
CC {ECO:0000255|HAMAP-Rule:MF_01320}.
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DR EMBL; AB000111; BAA22452.1; -; Genomic_DNA.
DR EMBL; AP008231; BAD80058.1; -; Genomic_DNA.
DR RefSeq; WP_011244178.1; NC_006576.1.
DR AlphaFoldDB; O24692; -.
DR SMR; O24692; -.
DR STRING; 269084.syc1868_d; -.
DR EnsemblBacteria; BAD80058; BAD80058; syc1868_d.
DR KEGG; syc:syc1868_d; -.
DR eggNOG; COG0090; Bacteria.
DR OMA; SCIELRP; -.
DR Proteomes; UP000001175; Chromosome.
DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 2.30.30.30; -; 1.
DR Gene3D; 2.40.50.140; -; 1.
DR Gene3D; 4.10.950.10; -; 1.
DR HAMAP; MF_01320_B; Ribosomal_L2_B; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR022666; Rbsml_prot_L2_RNA-bd_dom.
DR InterPro; IPR014722; Rib_L2_dom2.
DR InterPro; IPR002171; Ribosomal_L2.
DR InterPro; IPR005880; Ribosomal_L2_bac/org-type.
DR InterPro; IPR022669; Ribosomal_L2_C.
DR InterPro; IPR022671; Ribosomal_L2_CS.
DR InterPro; IPR014726; Ribosomal_L2_dom3.
DR InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR PANTHER; PTHR13691; PTHR13691; 1.
DR Pfam; PF00181; Ribosomal_L2; 1.
DR Pfam; PF03947; Ribosomal_L2_C; 1.
DR PIRSF; PIRSF002158; Ribosomal_L2; 1.
DR SMART; SM01383; Ribosomal_L2; 1.
DR SMART; SM01382; Ribosomal_L2_C; 1.
DR SUPFAM; SSF50104; SSF50104; 1.
DR SUPFAM; SSF50249; SSF50249; 1.
DR TIGRFAMs; TIGR01171; rplB_bact; 1.
DR PROSITE; PS00467; RIBOSOMAL_L2; 1.
PE 3: Inferred from homology;
KW Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding.
FT CHAIN 1..287
FT /note="50S ribosomal protein L2"
FT /id="PRO_0000129637"
FT REGION 216..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 268
FT /note="C -> R (in Ref. 1; BAA22452)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 287 AA; 31653 MW; B033BDC97DA19C22 CRC64;
MGIRAFRPYT PGTRERVVSD YAEITRNEPE KSLLVSKHRR KGRNNRGVIT CRHRGGGHKR
LYRIIDFKRD KRNVPGKIVS IEYDPNRNAR ISLVYYEDGE KRYILTPAGV HVGTPIIAGD
ETPIEVGNAM PLQNIPLGTT VHNVELVAGK GGQIVRAAGA SAQVVAKEGN YVALKLPSTE
VRLVRKECYA TIGAVGNAEV RNTSLGKAGR KRWLGRRPEV RGSVMNPVDH PHGGGEGRAP
IGRSGPVTPW GKPALGRKTR KKNKQSDCLI QRRRRKSSKR GRGGRDA
