ID   RL31B_BACSU             Reviewed;          82 AA.
AC   O34967;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 126.
DE   RecName: Full=50S ribosomal protein L31 type B;
GN   Name=rpmE2; Synonyms=ytiA; OrderedLocusNames=BSU30700;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9387221; DOI=10.1099/00221287-143-11-3431;
RA   Lapidus A., Galleron N., Sorokin A., Ehrlich S.D.;
RT   "Sequencing and functional annotation of the Bacillus subtilis genes in the
RT   200 kb rrnB-dnaB region.";
RL   Microbiology 143:3431-3441(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   DISCUSSION OF POSSIBLE REGULATION.
RC   STRAIN=168;
RX   PubMed=12904577; DOI=10.1073/pnas.1733691100;
RA   Panina E.M., Mironov A.A., Gelfand M.S.;
RT   "Comparative genomics of bacterial zinc regulons: enhanced ion transport,
RT   pathogenesis, and rearrangement of ribosomal proteins.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:9912-9917(2003).
RN   [4]
RP   IDENTIFICATION, AND CHARACTERIZATION OF GROWTH-PHASE DEPENDENT EXPRESSION.
RC   STRAIN=168;
RX   PubMed=15049826; DOI=10.1111/j.1365-2958.2003.03972.x;
RA   Nanamiya H., Akanuma G., Natori Y., Murayama R., Kosono S., Kudo T.,
RA   Kobayashi K., Ogasawara N., Park S.-M., Ochi K., Kawamura F.;
RT   "Zinc is a key factor in controlling alternation of two types of L31
RT   protein in the Bacillus subtilis ribosome.";
RL   Mol. Microbiol. 52:273-283(2004).
RN   [5]
RP   ALTERNATION OF L31 PARALOGS IN THE RIBOSOME.
RX   PubMed=16547061; DOI=10.1128/jb.188.7.2715-2720.2006;
RA   Akanuma G., Nanamiya H., Natori Y., Nomura N., Kawamura F.;
RT   "Liberation of zinc-containing L31 (rpmE) from ribosomes by its paralogous
RT   gene product, ytiA, in Bacillus subtilis.";
RL   J. Bacteriol. 188:2715-2720(2006).
CC   -!- FUNCTION: While neither of the L31 paralogs is essential, this protein
CC       does not seem to function as the main L31 protein. Has a higher
CC       affinity for 70S ribosomes than the zinc-containing L31 paralog; is
CC       able to displace it to varying extents, even under zinc-replete
CC       conditions. {ECO:0000269|PubMed:15049826}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit after the end of exponential
CC       growth. {ECO:0000269|PubMed:15049826}.
CC   -!- INDUCTION: Only found in ribosomes after the end of exponential growth.
CC       In PubMed:12904577 its expression was predicted to be repressed by the
CC       zinc-specific metallo-regulatory protein zur; in PubMed:15049826 it was
CC       shown that its expression is indeed repressed by zur.
CC       {ECO:0000269|PubMed:15049826, ECO:0000305|PubMed:12904577}.
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL31 family.
CC       Type B subfamily. {ECO:0000305}.
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DR   EMBL; AF008220; AAC00233.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15048.1; -; Genomic_DNA.
DR   PIR; E69993; E69993.
DR   RefSeq; NP_390948.1; NC_000964.3.
DR   RefSeq; WP_003219346.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; O34967; -.
DR   IntAct; O34967; 1.
DR   MINT; O34967; -.
DR   STRING; 224308.BSU30700; -.
DR   PaxDb; O34967; -.
DR   PRIDE; O34967; -.
DR   EnsemblBacteria; CAB15048; CAB15048; BSU_30700.
DR   GeneID; 64304789; -.
DR   GeneID; 937208; -.
DR   KEGG; bsu:BSU30700; -.
DR   PATRIC; fig|224308.179.peg.3328; -.
DR   eggNOG; COG0254; Bacteria.
DR   InParanoid; O34967; -.
DR   OMA; FKDMSND; -.
DR   PhylomeDB; O34967; -.
DR   BioCyc; BSUB:BSU30700-MON; -.
DR   PRO; PR:O34967; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   Gene3D; 4.10.830.30; -; 1.
DR   HAMAP; MF_00502; Ribosomal_L31_2; 1.
DR   InterPro; IPR034704; L28p-like.
DR   InterPro; IPR002150; Ribosomal_L31.
DR   InterPro; IPR027493; Ribosomal_L31_B.
DR   InterPro; IPR042105; Ribosomal_L31_sf.
DR   PANTHER; PTHR33280; PTHR33280; 1.
DR   Pfam; PF01197; Ribosomal_L31; 1.
DR   PRINTS; PR01249; RIBOSOMALL31.
DR   SUPFAM; SSF143800; SSF143800; 1.
DR   TIGRFAMs; TIGR00105; L31; 1.
DR   PROSITE; PS01143; RIBOSOMAL_L31; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..82
FT                   /note="50S ribosomal protein L31 type B"
FT                   /id="PRO_0000173204"
SQ   SEQUENCE   82 AA;  9531 MW;  224257A5592A6B81 CRC64;
     MKEGIHPKNH KVIFQDVNSG YRFLSTSTKT SNETAEWEDG NTYPVIKVEV SSDTHPFYTG
     RQKFNEKGGR VEQFKKRYNM GK