RL31_STRCO
ID RL31_STRCO Reviewed; 74 AA.
AC Q9K4E5;
DT 05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=50S ribosomal protein L31;
GN Name=rpmE; OrderedLocusNames=SCO5359; ORFNames=2SC6G5.03;
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145;
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
RN [2]
RP INDUCTION.
RC STRAIN=A3(2) / M600;
RX PubMed=11737643; DOI=10.1046/j.1365-2958.2001.02675.x;
RA Paget M.S.B., Molle V., Cohen G., Aharonowitz Y., Buttner M.J.;
RT "Defining the disulphide stress response in Streptomyces coelicolor A3(2):
RT identification of the sigmaR regulon.";
RL Mol. Microbiol. 42:1007-1020(2001).
CC -!- FUNCTION: Binds the 23S rRNA. {ECO:0000250}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000250};
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000250}.
CC -!- INDUCTION: Induced in response to the thiol oxidant diamide, suggesting
CC it is part of a disulfide stress response system. Oxidation of L31 may
CC cause ribosome stalling, which would decrease the protein synthesis
CC rate, allowing the bacteria to concentrate on stress survival.
CC {ECO:0000269|PubMed:11737643}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL31 family.
CC Type A subfamily. {ECO:0000305}.
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DR EMBL; AL939123; CAB94530.1; -; Genomic_DNA.
DR RefSeq; NP_629498.1; NC_003888.3.
DR RefSeq; WP_003973638.1; NZ_VNID01000011.1.
DR AlphaFoldDB; Q9K4E5; -.
DR SMR; Q9K4E5; -.
DR STRING; 100226.SCO5359; -.
DR GeneID; 1100799; -.
DR KEGG; sco:SCO5359; -.
DR PATRIC; fig|100226.15.peg.5439; -.
DR eggNOG; COG0254; Bacteria.
DR HOGENOM; CLU_114306_4_3_11; -.
DR InParanoid; Q9K4E5; -.
DR OMA; WYPDAKV; -.
DR PhylomeDB; Q9K4E5; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 4.10.830.30; -; 1.
DR HAMAP; MF_00501; Ribosomal_L31_1; 1.
DR InterPro; IPR034704; L28p-like.
DR InterPro; IPR002150; Ribosomal_L31.
DR InterPro; IPR027491; Ribosomal_L31_A.
DR InterPro; IPR042105; Ribosomal_L31_sf.
DR PANTHER; PTHR33280; PTHR33280; 1.
DR Pfam; PF01197; Ribosomal_L31; 1.
DR PRINTS; PR01249; RIBOSOMALL31.
DR SUPFAM; SSF143800; SSF143800; 1.
DR TIGRFAMs; TIGR00105; L31; 1.
DR PROSITE; PS01143; RIBOSOMAL_L31; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding; Zinc.
FT CHAIN 1..74
FT /note="50S ribosomal protein L31"
FT /id="PRO_0000173164"
FT BINDING 16
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
FT BINDING 18
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
FT BINDING 38
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
FT BINDING 41
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
SQ SEQUENCE 74 AA; 8119 MW; 67604FAC14B430C8 CRC64;
MKRDIHPEYV ETQVSCTCGA SFTTRSTIES GTIRAEVCSE CHPFYTGKQK ILDTGGRVAR
FEARFGKASA GSKK
