RL34_PIG
ID RL34_PIG Reviewed; 117 AA.
AC Q29223; F2Z5B9;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 28-FEB-2018, sequence version 3.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=60S ribosomal protein L34;
GN Name=RPL34;
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Small intestine;
RX PubMed=8672129; DOI=10.1007/s003359900153;
RA Winteroe A.K., Fredholm M., Davies W.;
RT "Evaluation and characterization of a porcine small intestine cDNA library:
RT analysis of 839 clones.";
RL Mamm. Genome 7:509-517(1996).
RN [2] {ECO:0000312|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc;
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0007744|PDB:3J7O, ECO:0007744|PDB:3J7P, ECO:0007744|PDB:3J7Q}
RP STRUCTURE BY ELECTRON MICROSCOPY (3.40 ANGSTROMS), FUNCTION, SUBCELLULAR
RP LOCATION, AND SUBUNIT.
RX PubMed=24930395; DOI=10.1016/j.cell.2014.05.024;
RA Voorhees R.M., Fernandez I.S., Scheres S.H., Hegde R.S.;
RT "Structure of the mammalian ribosome-Sec61 complex to 3.4 A resolution.";
RL Cell 157:1632-1643(2014).
CC -!- FUNCTION: Component of the large ribosomal subunit (PubMed:24930395).
CC The ribosome is a large ribonucleoprotein complex responsible for the
CC synthesis of proteins in the cell (PubMed:24930395).
CC {ECO:0000269|PubMed:24930395}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000269|PubMed:24930395}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000250|UniProtKB:P49207}. Cytoplasm
CC {ECO:0000250|UniProtKB:P49207}. Endoplasmic reticulum
CC {ECO:0000269|PubMed:24930395}. Note=Detected on cytosolic polysomes (By
CC similarity). Detected in ribosomes that are associated with the rough
CC endoplasmic reticulum (PubMed:24930395). {ECO:0000250|UniProtKB:P49207,
CC ECO:0000269|PubMed:24930395}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL34 family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; F14815; CAA23273.1; -; mRNA.
DR EMBL; AEMK02000067; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005666999.1; XM_005666942.2.
DR RefSeq; XP_005667000.1; XM_005666943.2.
DR RefSeq; XP_013834418.1; XM_013978964.1.
DR RefSeq; XP_013834419.1; XM_013978965.1.
DR PDB; 3J7O; EM; 3.50 A; g=1-108.
DR PDB; 3J7P; EM; 3.50 A; g=1-108.
DR PDB; 3J7Q; EM; 3.50 A; g=1-108.
DR PDB; 3J7R; EM; 3.90 A; g=1-108.
DR PDBsum; 3J7O; -.
DR PDBsum; 3J7P; -.
DR PDBsum; 3J7Q; -.
DR PDBsum; 3J7R; -.
DR AlphaFoldDB; Q29223; -.
DR SMR; Q29223; -.
DR STRING; 9823.ENSSSCP00000009753; -.
DR PeptideAtlas; Q29223; -.
DR PRIDE; Q29223; -.
DR Ensembl; ENSSSCT00000010015; ENSSSCP00000009753; ENSSSCG00000009146.
DR Ensembl; ENSSSCT00005063994; ENSSSCP00005039548; ENSSSCG00005039984.
DR Ensembl; ENSSSCT00015020909; ENSSSCP00015008217; ENSSSCG00015015743.
DR Ensembl; ENSSSCT00025052002; ENSSSCP00025022182; ENSSSCG00025038271.
DR Ensembl; ENSSSCT00030004938; ENSSSCP00030001962; ENSSSCG00030003785.
DR Ensembl; ENSSSCT00035028324; ENSSSCP00035010908; ENSSSCG00035021704.
DR Ensembl; ENSSSCT00040102900; ENSSSCP00040046537; ENSSSCG00040074412.
DR Ensembl; ENSSSCT00045043043; ENSSSCP00045029899; ENSSSCG00045025248.
DR Ensembl; ENSSSCT00050018619; ENSSSCP00050007687; ENSSSCG00050013820.
DR Ensembl; ENSSSCT00055014043; ENSSSCP00055011044; ENSSSCG00055007220.
DR Ensembl; ENSSSCT00060104990; ENSSSCP00060046067; ENSSSCG00060076495.
DR Ensembl; ENSSSCT00065010348; ENSSSCP00065004309; ENSSSCG00065007708.
DR Ensembl; ENSSSCT00070039451; ENSSSCP00070033045; ENSSSCG00070019891.
DR Ensembl; ENSSSCT00070039457; ENSSSCP00070033051; ENSSSCG00070019891.
DR GeneID; 100517840; -.
DR KEGG; ssc:100517840; -.
DR CTD; 6164; -.
DR VGNC; VGNC:98957; RPL34.
DR eggNOG; KOG1790; Eukaryota.
DR GeneTree; ENSGT00390000008294; -.
DR InParanoid; Q29223; -.
DR OMA; CGNCVKD; -.
DR OrthoDB; 1517591at2759; -.
DR TreeFam; TF314326; -.
DR Proteomes; UP000008227; Chromosome 8.
DR Proteomes; UP000314985; Chromosome 8.
DR Bgee; ENSSSCG00000009146; Expressed in forelimb bud and 47 other tissues.
DR Genevisible; F2Z5B9; SS.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR InterPro; IPR008195; Ribosomal_L34Ae.
DR InterPro; IPR018065; Ribosomal_L34e_CS.
DR Pfam; PF01199; Ribosomal_L34e; 1.
DR PRINTS; PR01250; RIBOSOMALL34.
DR PROSITE; PS01145; RIBOSOMAL_L34E; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acetylation; Cytoplasm; Endoplasmic reticulum;
KW Isopeptide bond; Phosphoprotein; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; Ubl conjugation.
FT CHAIN 1..117
FT /note="60S ribosomal protein L34"
FT /id="PRO_0000131833"
FT MOD_RES 12
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P49207"
FT MOD_RES 36
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:P49207"
FT MOD_RES 43
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:Q9D1R9"
FT CROSSLNK 108
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:P49207"
FT CONFLICT 75..83
FT /note="SRAYGGSMC -> QPGLWWFHV (in Ref. 1; CAA23273)"
SQ SEQUENCE 117 AA; 13293 MW; FC09D00B98CB770C CRC64;
MVQRLTYRRR LSYNTASNKT RLSRTPGNRI VYLYTKKVGK APKSACGVCP GRLRGVRAVR
PKVLMRLSKT KKHVSRAYGG SMCAKCVRDR IKRAFLIEEQ KIVVKVLKAQ AQSQKAK
