RL35A_BOVIN
ID RL35A_BOVIN Reviewed; 110 AA.
AC Q56JY1;
DT 13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=60S ribosomal protein L35a;
GN Name=RPL35A;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Lymphoid epithelium;
RA Yu J., Meng Y., Wang Z., Hansen C., Li C., Moore S.S.;
RT "Analysis of sequences obtained from constructed full-length bovine cDNA
RT libraries.";
RL Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Testis;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC large ribonucleoprotein complex responsible for the synthesis of
CC proteins in the cell. Required for the proliferation and viability of
CC hematopoietic cells. {ECO:0000250|UniProtKB:P18077}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:P18077}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P18077}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL33 family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY911347; AAW82114.1; -; mRNA.
DR EMBL; BC111654; AAI11655.1; -; mRNA.
DR RefSeq; NP_001020492.1; NM_001025321.3.
DR RefSeq; XP_005201446.1; XM_005201389.1.
DR RefSeq; XP_005201447.1; XM_005201390.2.
DR AlphaFoldDB; Q56JY1; -.
DR SMR; Q56JY1; -.
DR STRING; 9913.ENSBTAP00000050006; -.
DR PaxDb; Q56JY1; -.
DR PeptideAtlas; Q56JY1; -.
DR PRIDE; Q56JY1; -.
DR Ensembl; ENSBTAT00000018888; ENSBTAP00000018888; ENSBTAG00000014208.
DR GeneID; 506768; -.
DR KEGG; bta:506768; -.
DR CTD; 6165; -.
DR VEuPathDB; HostDB:ENSBTAG00000014208; -.
DR VGNC; VGNC:53601; RPL35A.
DR eggNOG; KOG0887; Eukaryota.
DR GeneTree; ENSGT00390000016972; -.
DR HOGENOM; CLU_100745_5_0_1; -.
DR InParanoid; Q56JY1; -.
DR OMA; FKRHGRL; -.
DR TreeFam; TF300104; -.
DR Proteomes; UP000009136; Chromosome 1.
DR Bgee; ENSBTAG00000014208; Expressed in pharyngeal tonsil and 104 other tissues.
DR ExpressionAtlas; Q56JY1; baseline and differential.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR Gene3D; 2.40.10.190; -; 1.
DR HAMAP; MF_00573; Ribosomal_L35Ae; 1.
DR InterPro; IPR038661; L35A_sf.
DR InterPro; IPR001780; Ribosomal_L35A.
DR InterPro; IPR018266; Ribosomal_L35Ae_CS.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR PANTHER; PTHR10902; PTHR10902; 1.
DR Pfam; PF01247; Ribosomal_L35Ae; 1.
DR SUPFAM; SSF50447; SSF50447; 1.
DR PROSITE; PS01105; RIBOSOMAL_L35AE; 1.
PE 3: Inferred from homology;
KW Acetylation; Cytoplasm; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; RNA-binding; tRNA-binding.
FT CHAIN 1..110
FT /note="60S ribosomal protein L35a"
FT /id="PRO_0000240151"
FT MOD_RES 8
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:P18077"
FT MOD_RES 63
FT /note="N6-acetyllysine; alternate"
FT /evidence="ECO:0000250|UniProtKB:O55142"
FT MOD_RES 63
FT /note="N6-succinyllysine; alternate"
FT /evidence="ECO:0000250|UniProtKB:O55142"
SQ SEQUENCE 110 AA; 12552 MW; F32E4A26B1E64278 CRC64;
MSGRLWSKAI FAGYKRGLRN QREHTALLKI EGVYARDETE FYLGKRCAYV YKAKNNTVTP
GGKPNKTRVI WGKITRAHGN SGMVRAKFRS NLPAKAIGHR IRVMLYPSRI