RL35A_PONAB
ID RL35A_PONAB Reviewed; 110 AA.
AC Q5R8K6;
DT 29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=60S ribosomal protein L35a;
GN Name=RPL35A;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC large ribonucleoprotein complex responsible for the synthesis of
CC proteins in the cell. Required for the proliferation and viability of
CC hematopoietic cells. {ECO:0000250|UniProtKB:P18077}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:P18077}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P18077}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL33 family.
CC {ECO:0000305}.
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DR EMBL; CR859746; CAH91904.1; -; mRNA.
DR RefSeq; NP_001126102.1; NM_001132630.1.
DR RefSeq; XP_009237982.1; XM_009239707.1.
DR AlphaFoldDB; Q5R8K6; -.
DR SMR; Q5R8K6; -.
DR STRING; 9601.ENSPPYP00000016170; -.
DR Ensembl; ENSPPYT00000055077; ENSPPYP00000043881; ENSPPYG00000030262.
DR GeneID; 100173057; -.
DR KEGG; pon:100173057; -.
DR CTD; 6165; -.
DR eggNOG; KOG0887; Eukaryota.
DR GeneTree; ENSGT00390000016972; -.
DR HOGENOM; CLU_100745_5_0_1; -.
DR InParanoid; Q5R8K6; -.
DR OMA; FKRHGRL; -.
DR OrthoDB; 1448743at2759; -.
DR TreeFam; TF300104; -.
DR Proteomes; UP000001595; Chromosome 3.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IEA:Ensembl.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:Ensembl.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:Ensembl.
DR GO; GO:0006364; P:rRNA processing; IEA:Ensembl.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 2.40.10.190; -; 1.
DR HAMAP; MF_00573; Ribosomal_L35Ae; 1.
DR InterPro; IPR038661; L35A_sf.
DR InterPro; IPR001780; Ribosomal_L35A.
DR InterPro; IPR018266; Ribosomal_L35Ae_CS.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR PANTHER; PTHR10902; PTHR10902; 1.
DR Pfam; PF01247; Ribosomal_L35Ae; 1.
DR SUPFAM; SSF50447; SSF50447; 1.
DR PROSITE; PS01105; RIBOSOMAL_L35AE; 1.
PE 3: Inferred from homology;
KW Acetylation; Cytoplasm; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; RNA-binding; tRNA-binding.
FT CHAIN 1..110
FT /note="60S ribosomal protein L35a"
FT /id="PRO_0000192799"
FT MOD_RES 8
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:P18077"
FT MOD_RES 63
FT /note="N6-acetyllysine; alternate"
FT /evidence="ECO:0000250|UniProtKB:O55142"
FT MOD_RES 63
FT /note="N6-succinyllysine; alternate"
FT /evidence="ECO:0000250|UniProtKB:O55142"
SQ SEQUENCE 110 AA; 12538 MW; F32E4A26A25E79E8 CRC64;
MSGRLWSKAI FAGYKRGLRN QREHTALLKI EGVYARDETE FYLGKRCAYV YKAKNNTVTP
GGKPNKTRVI WGKVTRAHGN SGMVRAKFRS NLPAKAIGHR IRVMLYPSRI