ID   RL36A_MOUSE             Reviewed;         106 AA.
AC   P83882; P09896; P10661;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 146.
DE   RecName: Full=60S ribosomal protein L36a;
DE   AltName: Full=60S ribosomal protein L44;
GN   Name=Rpl36a; Synonyms=Rpl44;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=C129;
RX   PubMed=7626884; DOI=10.1007/bf00364796;
RA   Oeltjen J.C., Liu X., Lu J., Allen R.C., Muzny D.M., Belmont J.W.,
RA   Gibbs R.A.;
RT   "Sixty-nine kilobases of contiguous human genomic sequence containing the
RT   alpha-galactosidase A and Bruton's tyrosine kinase loci.";
RL   Mamm. Genome 6:334-338(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Kidney;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Brain, and Mammary gland;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:P83881}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P83881}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P83881}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL42 family.
CC       {ECO:0000305}.
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DR   EMBL; U58105; AAB47245.1; -; Genomic_DNA.
DR   EMBL; AK002540; BAB22175.1; -; mRNA.
DR   EMBL; AK003166; BAB22616.1; -; mRNA.
DR   EMBL; AK010629; BAB27075.1; -; mRNA.
DR   EMBL; AK012502; BAB28285.1; -; mRNA.
DR   EMBL; BC019810; AAH19810.1; -; mRNA.
DR   EMBL; BC027515; AAH27515.1; -; mRNA.
DR   EMBL; BC081439; AAH81439.1; -; mRNA.
DR   EMBL; BC081440; AAH81440.1; -; mRNA.
DR   CCDS; CCDS41123.1; -.
DR   RefSeq; NP_063918.1; NM_019865.5.
DR   RefSeq; NP_079865.1; NM_025589.4.
DR   PDB; 7CPU; EM; 2.82 A; Lo=1-106.
DR   PDB; 7CPV; EM; 3.03 A; Lo=1-106.
DR   PDB; 7LS1; EM; 3.30 A; i2=1-106.
DR   PDB; 7LS2; EM; 3.10 A; i2=1-106.
DR   PDBsum; 7CPU; -.
DR   PDBsum; 7CPV; -.
DR   PDBsum; 7LS1; -.
DR   PDBsum; 7LS2; -.
DR   AlphaFoldDB; P83882; -.
DR   SMR; P83882; -.
DR   BioGRID; 202985; 50.
DR   BioGRID; 211507; 4.
DR   ComplexPortal; CPX-5262; 60S cytosolic large ribosomal subunit.
DR   STRING; 10090.ENSMUSP00000106249; -.
DR   iPTMnet; P83882; -.
DR   PhosphoSitePlus; P83882; -.
DR   SwissPalm; P83882; -.
DR   EPD; P83882; -.
DR   jPOST; P83882; -.
DR   PaxDb; P83882; -.
DR   PeptideAtlas; P83882; -.
DR   PRIDE; P83882; -.
DR   ProteomicsDB; 253310; -.
DR   TopDownProteomics; P83882; -.
DR   Antibodypedia; 34835; 128 antibodies from 19 providers.
DR   DNASU; 19982; -.
DR   DNASU; 66483; -.
DR   Ensembl; ENSMUST00000054544; ENSMUSP00000059766; ENSMUSG00000049751.
DR   Ensembl; ENSMUST00000110619; ENSMUSP00000106249; ENSMUSG00000049751.
DR   Ensembl; ENSMUST00000110620; ENSMUSP00000106250; ENSMUSG00000049751.
DR   Ensembl; ENSMUST00000113211; ENSMUSP00000108837; ENSMUSG00000079435.
DR   GeneID; 19982; -.
DR   GeneID; 66483; -.
DR   KEGG; mmu:19982; -.
DR   KEGG; mmu:66483; -.
DR   UCSC; uc007nrs.2; mouse.
DR   CTD; 6166; -.
DR   CTD; 6173; -.
DR   MGI; MGI:1201789; Rpl36a.
DR   VEuPathDB; HostDB:ENSMUSG00000049751; -.
DR   VEuPathDB; HostDB:ENSMUSG00000079435; -.
DR   eggNOG; KOG3464; Eukaryota.
DR   GeneTree; ENSGT00390000018085; -.
DR   HOGENOM; CLU_114645_2_1_1; -.
DR   InParanoid; P83882; -.
DR   OMA; CKKHTIH; -.
DR   OrthoDB; 1392093at2759; -.
DR   PhylomeDB; P83882; -.
DR   TreeFam; TF300213; -.
DR   Reactome; R-MMU-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-MMU-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-MMU-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-MMU-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-MMU-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-MMU-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-MMU-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   BioGRID-ORCS; 19982; 19 hits in 54 CRISPR screens.
DR   BioGRID-ORCS; 66483; 21 hits in 71 CRISPR screens.
DR   ChiTaRS; Rpl36a; mouse.
DR   PRO; PR:P83882; -.
DR   Proteomes; UP000000589; Chromosome 12.
DR   Proteomes; UP000000589; Chromosome X.
DR   RNAct; P83882; protein.
DR   Bgee; ENSMUSG00000049751; Expressed in yolk sac and 62 other tissues.
DR   ExpressionAtlas; P83882; baseline and differential.
DR   Genevisible; P83882; MM.
DR   GO; GO:0005737; C:cytoplasm; IC:ComplexPortal.
DR   GO; GO:0005829; C:cytosol; ISO:MGI.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IPI:ComplexPortal.
DR   GO; GO:0022626; C:cytosolic ribosome; ISO:MGI.
DR   GO; GO:0005783; C:endoplasmic reticulum; ISO:MGI.
DR   GO; GO:0005886; C:plasma membrane; ISO:MGI.
DR   GO; GO:0042788; C:polysomal ribosome; ISO:MGI.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISO:MGI.
DR   GO; GO:0002181; P:cytoplasmic translation; IC:ComplexPortal.
DR   InterPro; IPR000552; Ribosomal_L44e.
DR   InterPro; IPR011332; Ribosomal_zn-bd.
DR   PANTHER; PTHR10369; PTHR10369; 1.
DR   Pfam; PF00935; Ribosomal_L44; 1.
DR   SUPFAM; SSF57829; SSF57829; 1.
DR   PROSITE; PS01172; RIBOSOMAL_L44E; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein.
FT   CHAIN           1..106
FT                   /note="60S ribosomal protein L36a"
FT                   /id="PRO_0000149120"
FT   REGION          34..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   106 AA;  12441 MW;  AE3308265D70BD26 CRC64;
     MVNVPKTRRT FCKKCGKHQP HKVTQYKKGK DSLYAQGKRR YDRKQSGYGG QTKPIFRKKA
     KTTKKIVLRL ECVEPNCRSK RMLAIKRCKH FELGGDKKRK GQVIQF