RL36_DANRE
ID RL36_DANRE Reviewed; 105 AA.
AC Q6Q415;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=60S ribosomal protein L36;
GN Name=rpl36;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=15138505; DOI=10.1371/journal.pbio.0020139;
RA Amsterdam A., Sadler K.C., Lai K., Farrington S., Bronson R.T., Lees J.A.,
RA Hopkins N.;
RT "Many ribosomal protein genes are cancer genes in zebrafish.";
RL PLoS Biol. 2:690-698(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC large ribonucleoprotein complex responsible for the synthesis of
CC proteins in the cell. {ECO:0000250|UniProtKB:Q9Y3U8}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:Q9Y3U8}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000250|UniProtKB:Q9Y3U8}. Cytoplasm
CC {ECO:0000250|UniProtKB:Q9Y3U8}. Note=Detected on cytosolic polysomes.
CC {ECO:0000250|UniProtKB:Q2YGT9, ECO:0000250|UniProtKB:Q9Y3U8}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL36 family.
CC {ECO:0000305}.
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DR EMBL; AY561518; AAS66971.1; -; mRNA.
DR EMBL; BC071384; AAH71384.1; -; mRNA.
DR RefSeq; NP_998117.1; NM_212952.2.
DR RefSeq; XP_005170408.1; XM_005170351.3.
DR AlphaFoldDB; Q6Q415; -.
DR SMR; Q6Q415; -.
DR STRING; 7955.ENSDARP00000124304; -.
DR PaxDb; Q6Q415; -.
DR Ensembl; ENSDART00000161212; ENSDARP00000141617; ENSDARG00000100588.
DR Ensembl; ENSDART00000163327; ENSDARP00000138386; ENSDARG00000100588.
DR GeneID; 405888; -.
DR KEGG; dre:405888; -.
DR CTD; 25873; -.
DR ZFIN; ZDB-GENE-040622-2; rpl36.
DR eggNOG; KOG3452; Eukaryota.
DR GeneTree; ENSGT00390000011943; -.
DR HOGENOM; CLU_140672_0_0_1; -.
DR InParanoid; Q6Q415; -.
DR OMA; KGRQTKH; -.
DR OrthoDB; 1477459at2759; -.
DR PhylomeDB; Q6Q415; -.
DR TreeFam; TF314463; -.
DR Reactome; R-DRE-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-DRE-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-DRE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-DRE-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-DRE-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-DRE-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-DRE-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:Q6Q415; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 22.
DR Bgee; ENSDARG00000100588; Expressed in tail bud paraxial mesoderm and 32 other tissues.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0007420; P:brain development; IMP:ZFIN.
DR GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR GO; GO:0051726; P:regulation of cell cycle; IMP:ZFIN.
DR Gene3D; 1.10.10.1760; -; 1.
DR InterPro; IPR038097; L36e_sf.
DR InterPro; IPR000509; Ribosomal_L36e.
DR PANTHER; PTHR10114; PTHR10114; 1.
DR Pfam; PF01158; Ribosomal_L36e; 1.
DR PROSITE; PS01190; RIBOSOMAL_L36E; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..105
FT /note="60S ribosomal protein L36"
FT /id="PRO_0000318981"
SQ SEQUENCE 105 AA; 12180 MW; B2F62D0DCFC5B01B CRC64;
MVVRYPMAVG LNKGHKVTKN VSKPKHSRRR GRLTKHAKFA RDLIREVCGF APYERRAMEL
LKVSKDKRAL KFIKKRVGTH IRAKRKREEL SNTLAAMRKA AAKKE