RL37A_CHICK
ID RL37A_CHICK Reviewed; 92 AA.
AC P32046;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=60S ribosomal protein L37a;
GN Name=RPL37A;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Embryo;
RX PubMed=1380836;
RA Toku S., Tanaka T.;
RT "The primary structure of chicken ribosomal protein L37a.";
RL Biochim. Biophys. Acta 1132:88-90(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC TISSUE=Liver;
RX PubMed=8477735; DOI=10.1111/j.1432-1033.1993.tb17735.x;
RA Machida M., Toku S., Kenmochi N., Tanaka T.;
RT "The structure of the gene encoding chicken ribosomal protein L37a.";
RL Eur. J. Biochem. 213:77-80(1993).
CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC large ribonucleoprotein complex responsible for the synthesis of
CC proteins in the cell. {ECO:0000250|UniProtKB:P61513}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:P61513}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P61513}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL43 family.
CC {ECO:0000305}.
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DR EMBL; D10731; BAA01575.1; -; mRNA.
DR EMBL; D14167; BAA03209.1; -; Genomic_DNA.
DR PIR; S24170; S24170.
DR RefSeq; NP_001072961.1; NM_001079493.2.
DR AlphaFoldDB; P32046; -.
DR SMR; P32046; -.
DR STRING; 9031.ENSGALP00000018679; -.
DR PaxDb; P32046; -.
DR Ensembl; ENSGALT00000018702; ENSGALP00000018679; ENSGALG00000011475.
DR GeneID; 769981; -.
DR KEGG; gga:769981; -.
DR CTD; 6168; -.
DR VEuPathDB; HostDB:geneid_769981; -.
DR eggNOG; KOG0402; Eukaryota.
DR GeneTree; ENSGT00940000157608; -.
DR HOGENOM; CLU_141199_1_0_1; -.
DR InParanoid; P32046; -.
DR OrthoDB; 1621758at2759; -.
DR PhylomeDB; P32046; -.
DR PRO; PR:P32046; -.
DR Proteomes; UP000000539; Chromosome 7.
DR Bgee; ENSGALG00000011475; Expressed in spleen and 13 other tissues.
DR ExpressionAtlas; P32046; baseline and differential.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IEA:UniProt.
DR GO; GO:0043596; C:nuclear replication fork; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR GO; GO:0031297; P:replication fork processing; IBA:GO_Central.
DR GO; GO:0048478; P:replication fork protection; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 2.20.25.30; -; 1.
DR HAMAP; MF_00327; Ribosomal_L37Ae; 1.
DR InterPro; IPR002674; Ribosomal_L37ae.
DR InterPro; IPR011331; Ribosomal_L37ae/L37e.
DR InterPro; IPR011332; Ribosomal_zn-bd.
DR Pfam; PF01780; Ribosomal_L37ae; 1.
DR SUPFAM; SSF57829; SSF57829; 1.
DR TIGRFAMs; TIGR00280; eL43_euk_arch; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Metal-binding; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; Zinc; Zinc-finger.
FT CHAIN 1..92
FT /note="60S ribosomal protein L37a"
FT /id="PRO_0000139820"
FT ZN_FING 39..60
FT /note="C4-type"
FT BINDING 39
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P49166"
FT BINDING 42
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P49166"
FT BINDING 57
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P49166"
FT BINDING 60
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P49166"
SQ SEQUENCE 92 AA; 10247 MW; 7122B1488C0F4CF6 CRC64;
MAKRTKKVGI VGKYGTRYGA SLRKMVKKIE ISQHAKYTCS FCGKTKMKRK AVGIWHCGSC
MKTVAGGAWT YNTTSAVTVK SAIRRLKELK DQ