RL37A_HALSA
ID RL37A_HALSA Reviewed; 95 AA.
AC Q9HSG8;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 27-APR-2001, sequence version 2.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=50S ribosomal protein L37Ae {ECO:0000255|HAMAP-Rule:MF_00327};
DE AltName: Full=Ribosomal protein L43e {ECO:0000255|HAMAP-Rule:MF_00327};
GN Name=rpl37ae {ECO:0000255|HAMAP-Rule:MF_00327};
GN OrderedLocusNames=VNG_0239C;
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium.
OX NCBI_TaxID=64091;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC -!- FUNCTION: Binds to the 23S rRNA. {ECO:0000255|HAMAP-Rule:MF_00327}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00327};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000255|HAMAP-Rule:MF_00327};
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_00327}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL43 family.
CC Putative zinc-binding subfamily. {ECO:0000255|HAMAP-Rule:MF_00327}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG18838.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AE004437; AAG18838.1; ALT_INIT; Genomic_DNA.
DR PIR; B84184; B84184.
DR RefSeq; WP_012289127.1; NC_002607.1.
DR AlphaFoldDB; Q9HSG8; -.
DR SMR; Q9HSG8; -.
DR STRING; 64091.VNG_0239C; -.
DR PaxDb; Q9HSG8; -.
DR EnsemblBacteria; AAG18838; AAG18838; VNG_0239C.
DR GeneID; 5954257; -.
DR GeneID; 62885948; -.
DR KEGG; hal:VNG_0239C; -.
DR PATRIC; fig|64091.14.peg.172; -.
DR HOGENOM; CLU_141199_2_0_2; -.
DR InParanoid; Q9HSG8; -.
DR PhylomeDB; Q9HSG8; -.
DR Proteomes; UP000000554; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0070180; F:large ribosomal subunit rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 2.20.25.30; -; 1.
DR HAMAP; MF_00327; Ribosomal_L37Ae; 1.
DR InterPro; IPR002674; Ribosomal_L37ae.
DR InterPro; IPR011331; Ribosomal_L37ae/L37e.
DR InterPro; IPR011332; Ribosomal_zn-bd.
DR Pfam; PF01780; Ribosomal_L37ae; 1.
DR SUPFAM; SSF57829; SSF57829; 1.
DR TIGRFAMs; TIGR00280; eL43_euk_arch; 1.
PE 3: Inferred from homology;
KW Metal-binding; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding; Zinc; Zinc-finger.
FT CHAIN 1..95
FT /note="50S ribosomal protein L37Ae"
FT /id="PRO_0000139842"
FT ZN_FING 38..59
FT /note="C4-type"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00327"
FT BINDING 38
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00327"
FT BINDING 41
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00327"
FT BINDING 56
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00327"
FT BINDING 59
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00327"
SQ SEQUENCE 95 AA; 10028 MW; 85490A5B42F6A2C2 CRC64;
MANQSSTGSA GRFGARYGRV SRRRVSDIEG TMNEDHACPD CGSEAVSREG TGIWQCGKCG
YKYAGGAYQP QTPSGKTVTR SIRTALGETG DSNSE